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Reduced sympathoneural responses to the cold pressor test

MedGen UID:: 1052727
•Concept ID:: CN377132
•: Finding

HPO:	HP:6000323

Definition

Response to the cold pressor test below the lower limit of normal. The cold pressor test is a simple and validated test in which the subject immerses one hand or foot into ice water for 1 to 3 minutes while blood pressure (BP) and heart rate are monitored. The cold stimulus activates afferent sensory pathways that, in turn, trigger a sympathetic response resulting in an increase in BP. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVReduced sympathoneural responses to the cold pressor test

Fetal anomaly
- Congenital Systemic Disorder
  - Abnormality of the nervous system
    - Abnormality of the peripheral nervous system
      - Abnormality of the autonomic nervous system
        Abnormal autonomic nervous system physiology
        Reduced sympathoneural responses to the cold pressor test

Professional guidelines

PubMed

Reduced sympathoneural responses to the cold pressor test in individuals with essential hypertension and in those genetically predisposed to hypertension. No support for the "pressor reactor" hypothesis of hypertension development.

Lambert EA, Schlaich MP
Am J Hypertens 2004 Oct;17(10):863-8. doi: 10.1016/j.amjhyper.2004.05.008. PMID: 15485746

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