U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Draining sinus tract in skin

MedGen UID:
1053243
•Concept ID:
CN376607
•
Finding
Synonyms: Discharging sinus; Draining tract in skin; Tract under skin draining associated abscess
 
HPO: HP:6000095

Definition

A sinus tract is an abnormal channel that originates from the skin or a mucous surface to a deep-seated focus of suppuration. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDraining sinus tract in skin

Professional guidelines

PubMed

An Update on Current Clinical Management and Emerging Treatments in Hidradenitis Suppurativa.
Miller A, Shahzeidi P, Bernhardt M
Skin Therapy Lett 2024 Mar;29(2):1-6. PMID: 38574201
Clinical Implementation of Biologics and Small Molecules in the Treatment of Hidradenitis Suppurativa.
Aarts P, Dudink K, Vossen ARJV, van Straalen KR, Ardon CB, Prens EP, van der Zee HH
Drugs 2021 Aug;81(12):1397-1410. Epub 2021 Jul 20 doi: 10.1007/s40265-021-01566-2. PMID: 34283386Free PMC Article
Novel Therapeutic Approaches and Targets for the Treatment of Hidradenitis Suppurativa.
Giuffrida R, Cannavò SP, Coppola M, Guarneri C
Curr Pharm Biotechnol 2021;22(1):59-72. doi: 10.2174/1389201021666200505100556. PMID: 32368973

Recent clinical studies

Etiology

Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life.
Nguyen TV, Damiani G, Orenstein LAV, Hamzavi I, Jemec GB
J Eur Acad Dermatol Venereol 2021 Jan;35(1):50-61. Epub 2020 Jul 16 doi: 10.1111/jdv.16677. PMID: 32460374
Cutaneous squamous cell carcinoma complicating hidradenitis suppurativa: a review of the prevalence, pathogenesis, and treatment of this dreaded complication.
Chapman S, Delgadillo D III, Barber C, Khachemoune A
Acta Dermatovenerol Alp Pannonica Adriat 2018 Mar;27(1):25-28. PMID: 29589641
Pilonidal sinus disease and tuberculosis.
Gupta PJ
Eur Rev Med Pharmacol Sci 2012 Jan;16(1):19-24. PMID: 22338544
Abdominal wall gossypiboma.
Huston TL, Grant RT
J Plast Reconstr Aesthet Surg 2010 May;63(5):e463-4. Epub 2009 Aug 15 doi: 10.1016/j.bjps.2009.07.034. PMID: 19683975
Hidradenitis suppurativa.
Revuz J
J Eur Acad Dermatol Venereol 2009 Sep;23(9):985-98. doi: 10.1111/j.1468-3083.2009.03356.x. PMID: 19682181

Diagnosis

Update on Hormonal Therapy in Hidradenitis Suppurativa.
Karagaiah P, Daveluy S, Ortega-Loayza A, Gulliver W, Szepietowski J, Grabbe S, Goldust M
J Drugs Dermatol 2023 Apr 1;22(4):369-374. doi: 10.36849/JDD.6235. PMID: 37026880
Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life.
Nguyen TV, Damiani G, Orenstein LAV, Hamzavi I, Jemec GB
J Eur Acad Dermatol Venereol 2021 Jan;35(1):50-61. Epub 2020 Jul 16 doi: 10.1111/jdv.16677. PMID: 32460374
Hidradenitis Suppurativa.
Kawak S
Dis Colon Rectum 2019 Nov;62(11):1278-1280. doi: 10.1097/DCR.0000000000001497. PMID: 31596759
Metabolic diseases: gout.
Falasca GF
Clin Dermatol 2006 Nov-Dec;24(6):498-508. doi: 10.1016/j.clindermatol.2006.07.015. PMID: 17113968
Pilonidal disease.
Hull TL, Wu J
Surg Clin North Am 2002 Dec;82(6):1169-85. doi: 10.1016/s0039-6109(02)00062-2. PMID: 12516846

Therapy

Update on Hormonal Therapy in Hidradenitis Suppurativa.
Karagaiah P, Daveluy S, Ortega-Loayza A, Gulliver W, Szepietowski J, Grabbe S, Goldust M
J Drugs Dermatol 2023 Apr 1;22(4):369-374. doi: 10.36849/JDD.6235. PMID: 37026880
Clinical Implementation of Biologics and Small Molecules in the Treatment of Hidradenitis Suppurativa.
Aarts P, Dudink K, Vossen ARJV, van Straalen KR, Ardon CB, Prens EP, van der Zee HH
Drugs 2021 Aug;81(12):1397-1410. Epub 2021 Jul 20 doi: 10.1007/s40265-021-01566-2. PMID: 34283386Free PMC Article
Hidradenitis Suppurativa.
Kawak S
Dis Colon Rectum 2019 Nov;62(11):1278-1280. doi: 10.1097/DCR.0000000000001497. PMID: 31596759
Hidradenitis suppurativa.
Revuz J
J Eur Acad Dermatol Venereol 2009 Sep;23(9):985-98. doi: 10.1111/j.1468-3083.2009.03356.x. PMID: 19682181
Metabolic diseases: gout.
Falasca GF
Clin Dermatol 2006 Nov-Dec;24(6):498-508. doi: 10.1016/j.clindermatol.2006.07.015. PMID: 17113968

Prognosis

Hidradenitis suppurativa: pathogenesis, clinical presentation, epidemiology, and comorbid associations.
Preda-Naumescu A, Ahmed HN, Mayo TT, Yusuf N
Int J Dermatol 2021 Nov;60(11):e449-e458. Epub 2021 Apr 22 doi: 10.1111/ijd.15579. PMID: 33890304
Transpubic variant of congenital prepubic sinus on magnetic resonance imaging.
Lei BZ, Wu G, Polito L, Horowitz M, Neuman J
Pediatr Radiol 2020 Jun;50(7):1010-1012. Epub 2020 Jan 24 doi: 10.1007/s00247-020-04619-y. PMID: 31980849
Cutaneous squamous cell carcinoma complicating hidradenitis suppurativa: a review of the prevalence, pathogenesis, and treatment of this dreaded complication.
Chapman S, Delgadillo D III, Barber C, Khachemoune A
Acta Dermatovenerol Alp Pannonica Adriat 2018 Mar;27(1):25-28. PMID: 29589641
Abdominal wall gossypiboma.
Huston TL, Grant RT
J Plast Reconstr Aesthet Surg 2010 May;63(5):e463-4. Epub 2009 Aug 15 doi: 10.1016/j.bjps.2009.07.034. PMID: 19683975
Comparison between three therapeutic modalities for non-complicated pilonidal sinus disease.
Mohamed HA, Kadry I, Adly S
Surgeon 2005 Apr;3(2):73-7. doi: 10.1016/s1479-666x(05)80065-4. PMID: 15861940

Clinical prediction guides

Granulomatous Panniculitis as a Complication of Subcutaneous Testosterone Pellet Therapy.
Patel MH, Brumfiel CM, Breen I, Glembocki D, Luber A
Skinmed 2023;21(3):203-204. Epub 2023 Aug 28 PMID: 37634108
Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life.
Nguyen TV, Damiani G, Orenstein LAV, Hamzavi I, Jemec GB
J Eur Acad Dermatol Venereol 2021 Jan;35(1):50-61. Epub 2020 Jul 16 doi: 10.1111/jdv.16677. PMID: 32460374
Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data.
Nikolakis G, Kyrgidis A, Zouboulis CC
Am J Clin Dermatol 2019 Aug;20(4):503-513. doi: 10.1007/s40257-019-00442-w. PMID: 31073704
Does wet hair in cold weather cause sinus headache and posterior eye pain? A possible mechanism through selective brain cooling system.
Kaya A, Calışkan H
Med Hypotheses 2012 Dec;79(6):744-5. Epub 2012 Sep 10 doi: 10.1016/j.mehy.2012.08.017. PMID: 22975448
Pilonidal sinus disease and tuberculosis.
Gupta PJ
Eur Rev Med Pharmacol Sci 2012 Jan;16(1):19-24. PMID: 22338544

Recent systematic reviews

Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data.
Nikolakis G, Kyrgidis A, Zouboulis CC
Am J Clin Dermatol 2019 Aug;20(4):503-513. doi: 10.1007/s40257-019-00442-w. PMID: 31073704

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...