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Abnormal seminal vesicle morphology

MedGen UID:
1053917
•Concept ID:
CN376703
•
Finding
HPO: HP:6000190

Definition

A structural abnormality of the seminal vesicle. The seminal vesicles are a pair of glands that also include the prostate gland and the bulbourethral glands and are located in the pelvis superior to the rectum, inferior to the fundus of the bladder and posterior to the prostate. The seminal vesicles contribute around 70% of the fluid that will eventually become semen. [from HPO]

Professional guidelines

PubMed

Classifying seminal vesicle cysts in the diagnosis and treatment of Zinner syndrome: A report of six cases and review of available literature.
Tan Z, Li B, Zhang L, Han P, Huang H, Taylor A, Li X
Andrologia 2020 Feb;52(1):e13397. Epub 2019 Nov 15 doi: 10.1111/and.13397. PMID: 31729082
Seminal vesicle abnormalities following prostatic artery embolization for the treatment of benign prostatic hyperplasia.
Zhang JL, Yuan K, Wang MQ, Yan JY, Wang Y, Zhang GD
BMC Urol 2018 Oct 24;18(1):92. doi: 10.1186/s12894-018-0407-7. PMID: 30355294Free PMC Article
Management of ejaculatory duct obstruction: etiology, diagnosis, and treatment.
Fisch H, Lambert SM, Goluboff ET
World J Urol 2006 Dec;24(6):604-10. doi: 10.1007/s00345-006-0129-4. PMID: 17077974

Recent clinical studies

Etiology

Cystoscopic Management of Prostatic Utricles.
Babu R, Chandrasekharam V
Urology 2021 Mar;149:e52-e55. Epub 2020 Sep 17 doi: 10.1016/j.urology.2020.09.005. PMID: 32949553
MRI in the evaluation of the azoospermic male.
Regent B, Skrobisz K, Kozak O, Matuszewski M, Studniarek M
Diagn Interv Radiol 2020 Jul;26(4):271-276. doi: 10.5152/dir.2019.19189. PMID: 32441653Free PMC Article
Classifying seminal vesicle cysts in the diagnosis and treatment of Zinner syndrome: A report of six cases and review of available literature.
Tan Z, Li B, Zhang L, Han P, Huang H, Taylor A, Li X
Andrologia 2020 Feb;52(1):e13397. Epub 2019 Nov 15 doi: 10.1111/and.13397. PMID: 31729082
Seminal vesicle intraepithelial neoplasia versus basal cell hyperplasia in a seminal vesicle.
Montironi R, Lopez-Beltran A, Cheng L, Galosi AB, Montorsi F, Scarpelli M
Eur Urol 2014 Oct;66(4):623-7. Epub 2014 Mar 4 doi: 10.1016/j.eururo.2014.02.054. PMID: 24631410
Androgens and male physiology the syndrome of 5alpha-reductase-2 deficiency.
Imperato-McGinley J, Zhu YS
Mol Cell Endocrinol 2002 Dec 30;198(1-2):51-9. doi: 10.1016/s0303-7207(02)00368-4. PMID: 12573814

Diagnosis

Imaging of seminal vesicles: a pictorial review.
Mohsen Y, Al-Kutoubi A
Abdom Radiol (NY) 2023 Nov;48(11):3469-3487. Epub 2023 Aug 25 doi: 10.1007/s00261-023-04019-4. PMID: 37624375
MRI in the evaluation of the azoospermic male.
Regent B, Skrobisz K, Kozak O, Matuszewski M, Studniarek M
Diagn Interv Radiol 2020 Jul;26(4):271-276. doi: 10.5152/dir.2019.19189. PMID: 32441653Free PMC Article
Classifying seminal vesicle cysts in the diagnosis and treatment of Zinner syndrome: A report of six cases and review of available literature.
Tan Z, Li B, Zhang L, Han P, Huang H, Taylor A, Li X
Andrologia 2020 Feb;52(1):e13397. Epub 2019 Nov 15 doi: 10.1111/and.13397. PMID: 31729082
Magnetic resonance imaging and clinical findings in seminal vesicle pathologies.
Ozmen Z, Aktas F, Uluocak N, Albayrak E, Altunkaş A, Çelikyay F
Int Braz J Urol 2018 Jan-Feb;44(1):86-94. doi: 10.1590/S1677-5538.IBJU.2017.0153. PMID: 28853814Free PMC Article
Seminal vesicle cysts and associated anomalies.
Patel B, Gujral S, Jefferson K, Evans S, Persad R
BJU Int 2002 Aug;90(3):265-71. doi: 10.1046/j.1464-410x.2002.02883.x. PMID: 12133063

Therapy

Occupational exposure to pesticides and consequences on male semen and fertility: a review.
Mehrpour O, Karrari P, Zamani N, Tsatsakis AM, Abdollahi M
Toxicol Lett 2014 Oct 15;230(2):146-56. Epub 2014 Jan 30 doi: 10.1016/j.toxlet.2014.01.029. PMID: 24487096
WITHDRAWN: Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia.
Vandekerckhove P, Lilford R, Vail A, Hughes E
Cochrane Database Syst Rev 2007 Jul 18;(4):CD000150. doi: 10.1002/14651858.CD000150. PMID: 17636603
Androgens and male physiology the syndrome of 5alpha-reductase-2 deficiency.
Imperato-McGinley J, Zhu YS
Mol Cell Endocrinol 2002 Dec 30;198(1-2):51-9. doi: 10.1016/s0303-7207(02)00368-4. PMID: 12573814
5alpha-reductase activity in the prostate.
Steers WD
Urology 2001 Dec;58(6 Suppl 1):17-24; discussion 24. doi: 10.1016/s0090-4295(01)01299-7. PMID: 11750244
Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia.
Vandekerckhove P, Lilford R, Vail A, Hughes E
Cochrane Database Syst Rev 2000;1996(2):CD000150. doi: 10.1002/14651858.CD000150. PMID: 10796496Free PMC Article

Prognosis

MRI in the evaluation of the azoospermic male.
Regent B, Skrobisz K, Kozak O, Matuszewski M, Studniarek M
Diagn Interv Radiol 2020 Jul;26(4):271-276. doi: 10.5152/dir.2019.19189. PMID: 32441653Free PMC Article
Prostate cancer reporting and staging: needle biopsy and radical prostatectomy specimens.
Grignon DJ
Mod Pathol 2018 Jan;31(S1):S96-109. doi: 10.1038/modpathol.2017.167. PMID: 29297497
Seminal vesicle intraepithelial neoplasia versus basal cell hyperplasia in a seminal vesicle.
Montironi R, Lopez-Beltran A, Cheng L, Galosi AB, Montorsi F, Scarpelli M
Eur Urol 2014 Oct;66(4):623-7. Epub 2014 Mar 4 doi: 10.1016/j.eururo.2014.02.054. PMID: 24631410
Seminal vesicle biopsies: an useful staging procedure-exposure of seminal vesicle biopsies protocol and review of the literature.
Montoya-Chinchilla R, Rosino-Sánchez A, Fernandez-Aparicio T, Cano-García MC, Hidalgo-Agulló G, Reina-Alcaina L, Carrillo-George C, Izquierdo-Morejón E, Miñana-López B
Int Urol Nephrol 2014 Jan;46(1):297-302. Epub 2013 Sep 15 doi: 10.1007/s11255-013-0473-4. PMID: 24036934
Interleukin 8 and the male genital tract.
Lotti F, Maggi M
J Reprod Immunol 2013 Nov;100(1):54-65. Epub 2013 Apr 20 doi: 10.1016/j.jri.2013.02.004. PMID: 23611586

Clinical prediction guides

MRI in the evaluation of the azoospermic male.
Regent B, Skrobisz K, Kozak O, Matuszewski M, Studniarek M
Diagn Interv Radiol 2020 Jul;26(4):271-276. doi: 10.5152/dir.2019.19189. PMID: 32441653Free PMC Article
Ultrasound of the male genital tract in relation to male reproductive health.
Lotti F, Maggi M
Hum Reprod Update 2015 Jan-Feb;21(1):56-83. Epub 2014 Jul 19 doi: 10.1093/humupd/dmu042. PMID: 25038770
Denonvilliers' fascia revisited.
Kim JH, Kinugasa Y, Hwang SE, Murakami G, Rodríguez-Vázquez JF, Cho BH
Surg Radiol Anat 2015 Mar;37(2):187-97. Epub 2014 Jul 10 doi: 10.1007/s00276-014-1336-0. PMID: 25008480
Interleukin 8 and the male genital tract.
Lotti F, Maggi M
J Reprod Immunol 2013 Nov;100(1):54-65. Epub 2013 Apr 20 doi: 10.1016/j.jri.2013.02.004. PMID: 23611586
Cystic fibrosis and reproduction.
Phillipson G
Reprod Fertil Dev 1998;10(1):113-9. doi: 10.1071/r98044. PMID: 9727601

Recent systematic reviews

Ultrasound of the male genital tract in relation to male reproductive health.
Lotti F, Maggi M
Hum Reprod Update 2015 Jan-Feb;21(1):56-83. Epub 2014 Jul 19 doi: 10.1093/humupd/dmu042. PMID: 25038770
WITHDRAWN: Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia.
Vandekerckhove P, Lilford R, Vail A, Hughes E
Cochrane Database Syst Rev 2007 Jul 18;(4):CD000150. doi: 10.1002/14651858.CD000150. PMID: 17636603
Androgens versus placebo or no treatment for idiopathic oligo/asthenospermia.
Vandekerckhove P, Lilford R, Vail A, Hughes E
Cochrane Database Syst Rev 2000;1996(2):CD000150. doi: 10.1002/14651858.CD000150. PMID: 10796496Free PMC Article

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