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Ocular cancer

MedGen UID:
105418
•Concept ID:
C0496836
•
Neoplastic Process
Synonyms: Cancer of Eye; Cancer of the Eye; Cancer, Eye; Cancers, Eye; Eye Cancer; Eye Cancers
SNOMED CT: Malignant neoplasm of eye (363461003); Malignant tumor of eye (363461003)
 
Monarch Initiative: MONDO:0002236

Definition

A primary or metastatic malignant neoplasm involving the structures of the eye (conjunctiva, cornea, uvea, retina), the lacrimal system, and the eyelid. Representative examples include melanoma, carcinoma, lymphoma, and retinoblastoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOcular cancer

Professional guidelines

PubMed

Revolutionizing ocular cancer management: a narrative review on exploring the potential role of ChatGPT.
Alotaibi SS, Rehman A, Hasnain M
Front Public Health 2023;11:1338215. Epub 2023 Dec 15 doi: 10.3389/fpubh.2023.1338215. PMID: 38192545Free PMC Article
Imaging Techniques in the Diagnosis and Management of Ocular Tumors: Prospects and Challenges.
Neupane R, Gaudana R, Boddu SHS
AAPS J 2018 Sep 5;20(6):97. doi: 10.1208/s12248-018-0259-9. PMID: 30187172
The management of retinoblastoma.
Fabian ID, Onadim Z, Karaa E, Duncan C, Chowdhury T, Scheimberg I, Ohnuma SI, Reddy MA, Sagoo MS
Oncogene 2018 Mar;37(12):1551-1560. Epub 2018 Jan 11 doi: 10.1038/s41388-017-0050-x. PMID: 29321667

Recent clinical studies

Etiology

Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma.
Peng CC, Sirivolu S, Pike S, Kim ME, Reiser B, Li HT, Liang G, Xu L, Berry JL
Int J Mol Sci 2023 Apr 6;24(7) doi: 10.3390/ijms24076825. PMID: 37047796Free PMC Article
A joinpoint and age-period-cohort analysis of ocular cancer secular trends in Iran from 2004 to 2016.
Abolhosseini M, Khorrami Z, Safi S, Akbari ME, Moshtaghion SM, Mohammadi SF, Kanavi MR, Karimi S
Sci Rep 2023 Jan 19;13(1):1074. doi: 10.1038/s41598-022-26349-x. PMID: 36658192Free PMC Article
The International Vitreoretinal B-Cell Lymphoma Registry: a protocol paper.
Smith JR, Farrall AL, Davis JL, de Boer JH, Hall AJ, Mochizuki M, Sen HN, Takase H, Ten Dam-van Loon NH, Touitou V, Vasconcelos-Santos DV, Wilson DJ, Yeh S, Radford MHB
BMJ Open 2022 Jul 28;12(7):e060701. doi: 10.1136/bmjopen-2021-060701. PMID: 35902200Free PMC Article
Living with xeroderma pigmentosum: comprehensive photoprotection for highly photosensitive patients.
Tamura D, DiGiovanna JJ, Khan SG, Kraemer KH
Photodermatol Photoimmunol Photomed 2014 Apr-Jun;30(2-3):146-52. Epub 2014 Feb 19 doi: 10.1111/phpp.12108. PMID: 24417420Free PMC Article
The pathology of ocular cancer.
Eagle RC Jr
Eye (Lond) 2013 Feb;27(2):128-36. Epub 2012 Nov 16 doi: 10.1038/eye.2012.237. PMID: 23154492Free PMC Article

Diagnosis

An update on inflammation in uveal melanoma.
Liau S, Wang JZ, Zagarella E, Paulus P, Dang NHQH, Rawling T, Murray M, Zhou F
Biochimie 2023 Sep;212:114-122. Epub 2023 Apr 25 doi: 10.1016/j.biochi.2023.04.013. PMID: 37105300
Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma.
Peng CC, Sirivolu S, Pike S, Kim ME, Reiser B, Li HT, Liang G, Xu L, Berry JL
Int J Mol Sci 2023 Apr 6;24(7) doi: 10.3390/ijms24076825. PMID: 37047796Free PMC Article
Contemporary management of retinoblastoma in the context of a low-resource country.
Ademola-Popoola DS, Opocher E, Reddy MA
Niger Postgrad Med J 2019 Apr-Jun;26(2):69-79. doi: 10.4103/npmj.npmj_21_19. PMID: 31187745
Imaging Techniques in the Diagnosis and Management of Ocular Tumors: Prospects and Challenges.
Neupane R, Gaudana R, Boddu SHS
AAPS J 2018 Sep 5;20(6):97. doi: 10.1208/s12248-018-0259-9. PMID: 30187172
The management of retinoblastoma.
Fabian ID, Onadim Z, Karaa E, Duncan C, Chowdhury T, Scheimberg I, Ohnuma SI, Reddy MA, Sagoo MS
Oncogene 2018 Mar;37(12):1551-1560. Epub 2018 Jan 11 doi: 10.1038/s41388-017-0050-x. PMID: 29321667

Therapy

Treatment of RB-deficient retinoblastoma with Aurora-A kinase inhibitor.
Yang W, Jiang XX, Zhao XY, Mao PA
Kaohsiung J Med Sci 2022 Mar;38(3):244-252. Epub 2021 Nov 6 doi: 10.1002/kjm2.12469. PMID: 34741392
Imaging Techniques in the Diagnosis and Management of Ocular Tumors: Prospects and Challenges.
Neupane R, Gaudana R, Boddu SHS
AAPS J 2018 Sep 5;20(6):97. doi: 10.1208/s12248-018-0259-9. PMID: 30187172
The management of retinoblastoma.
Fabian ID, Onadim Z, Karaa E, Duncan C, Chowdhury T, Scheimberg I, Ohnuma SI, Reddy MA, Sagoo MS
Oncogene 2018 Mar;37(12):1551-1560. Epub 2018 Jan 11 doi: 10.1038/s41388-017-0050-x. PMID: 29321667
Living with xeroderma pigmentosum: comprehensive photoprotection for highly photosensitive patients.
Tamura D, DiGiovanna JJ, Khan SG, Kraemer KH
Photodermatol Photoimmunol Photomed 2014 Apr-Jun;30(2-3):146-52. Epub 2014 Feb 19 doi: 10.1111/phpp.12108. PMID: 24417420Free PMC Article
Ocular effects of radiofrequency energy.
Elder JA
Bioelectromagnetics 2003;Suppl 6:S148-61. doi: 10.1002/bem.10117. PMID: 14628311

Prognosis

An update on inflammation in uveal melanoma.
Liau S, Wang JZ, Zagarella E, Paulus P, Dang NHQH, Rawling T, Murray M, Zhou F
Biochimie 2023 Sep;212:114-122. Epub 2023 Apr 25 doi: 10.1016/j.biochi.2023.04.013. PMID: 37105300
Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma.
Peng CC, Sirivolu S, Pike S, Kim ME, Reiser B, Li HT, Liang G, Xu L, Berry JL
Int J Mol Sci 2023 Apr 6;24(7) doi: 10.3390/ijms24076825. PMID: 37047796Free PMC Article
A joinpoint and age-period-cohort analysis of ocular cancer secular trends in Iran from 2004 to 2016.
Abolhosseini M, Khorrami Z, Safi S, Akbari ME, Moshtaghion SM, Mohammadi SF, Kanavi MR, Karimi S
Sci Rep 2023 Jan 19;13(1):1074. doi: 10.1038/s41598-022-26349-x. PMID: 36658192Free PMC Article
The unfolded protein response and the biology of uveal melanoma.
Zhang S, Wang K, Zhu X, Cherepanoff S, Conway RM, Madigan MC, Zhu L, Murray M, Zhou F
Biochimie 2022 Jun;197:9-18. Epub 2022 Jan 29 doi: 10.1016/j.biochi.2022.01.017. PMID: 35093452
The management of retinoblastoma.
Fabian ID, Onadim Z, Karaa E, Duncan C, Chowdhury T, Scheimberg I, Ohnuma SI, Reddy MA, Sagoo MS
Oncogene 2018 Mar;37(12):1551-1560. Epub 2018 Jan 11 doi: 10.1038/s41388-017-0050-x. PMID: 29321667

Clinical prediction guides

Diagnostic Aqueous Humor Proteome Predicts Metastatic Potential in Uveal Melanoma.
Peng CC, Sirivolu S, Pike S, Kim ME, Reiser B, Li HT, Liang G, Xu L, Berry JL
Int J Mol Sci 2023 Apr 6;24(7) doi: 10.3390/ijms24076825. PMID: 37047796Free PMC Article
A joinpoint and age-period-cohort analysis of ocular cancer secular trends in Iran from 2004 to 2016.
Abolhosseini M, Khorrami Z, Safi S, Akbari ME, Moshtaghion SM, Mohammadi SF, Kanavi MR, Karimi S
Sci Rep 2023 Jan 19;13(1):1074. doi: 10.1038/s41598-022-26349-x. PMID: 36658192Free PMC Article
The impact of the COVID-19 pandemic on the diagnosis and treatment of ocular cancer.
Fontes Junior VC, Fernandes AG, Morales MC, Belfort Neto R
Arq Bras Oftalmol 2023 Mar-Apr;86(2):127-130. doi: 10.5935/0004-2749.20230023. PMID: 35417515
Retinoblastoma, the visible CNS tumor: A review.
Dimaras H, Corson TW
J Neurosci Res 2019 Jan;97(1):29-44. Epub 2018 Jan 3 doi: 10.1002/jnr.24213. PMID: 29314142Free PMC Article
Uveal melanoma: A pathologist's perspective and review of translational developments.
Schoenfield L
Adv Anat Pathol 2014 Mar;21(2):138-43. doi: 10.1097/PAP.0000000000000010. PMID: 24508696

Recent systematic reviews

Quality of life among people with eye cancer: a systematic review from 2012 to 2022.
Huang Y, Guo Y
Health Qual Life Outcomes 2024 Jan 7;22(1):3. doi: 10.1186/s12955-023-02219-6. PMID: 38185647Free PMC Article

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