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Postoperative pain

MedGen UID:
10542
Concept ID:
C0030201
Sign or Symptom
Synonyms: Pain, Post operative; Pain, Post-operative; Pain, Post-surgical; Pain, Postoperative; Pain, Postsurgical; Post operative Pain; Post surgical Pain; Post-operative Pain; Post-operative Pains; Post-surgical Pain; Postoperative Pain; Postsurgical Pain
SNOMED CT: Postoperative pain (213299007)

Definition

A sensation of discomfort secondary to surgery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPostoperative pain

Professional guidelines

PubMed

Small C, Laycock H
Br J Surg 2020 Jan;107(2):e70-e80. doi: 10.1002/bjs.11477. PMID: 31903595
Li JW, Ma YS, Xiao LK
Orthop Surg 2019 Oct;11(5):755-761. doi: 10.1111/os.12535. PMID: 31663286Free PMC Article
Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Thirlby R, Viscusi E, Walco GA, Warner L, Weisman SJ, Wu CL
J Pain 2016 Feb;17(2):131-57. doi: 10.1016/j.jpain.2015.12.008. PMID: 26827847

Recent clinical studies

Etiology

Anger M, Valovska T, Beloeil H, Lirk P, Joshi GP, Van de Velde M, Raeder J; PROSPECT Working Group* and the European Society of Regional Anaesthesia and Pain Therapy
Anaesthesia 2021 Aug;76(8):1082-1097. Epub 2021 May 20 doi: 10.1111/anae.15498. PMID: 34015859
Chen YK, Boden KA, Schreiber KL
Anaesthesia 2021 Jan;76 Suppl 1(Suppl 1):8-17. doi: 10.1111/anae.15256. PMID: 33426669Free PMC Article
Zieliński J, Morawska-Kochman M, Zatoński T
Adv Clin Exp Med 2020 Mar;29(3):365-374. doi: 10.17219/acem/112600. PMID: 32129952
Rawal N
Eur J Anaesthesiol 2016 Mar;33(3):160-71. doi: 10.1097/EJA.0000000000000366. PMID: 26509324
Kehlet H, Jensen TS, Woolf CJ
Lancet 2006 May 13;367(9522):1618-25. doi: 10.1016/S0140-6736(06)68700-X. PMID: 16698416

Diagnosis

Waelkens P, Alsabbagh E, Sauter A, Joshi GP, Beloeil H; PROSPECT Working group∗∗ of the European Society of Regional Anaesthesia and Pain therapy (ESRA)
Eur J Anaesthesiol 2021 Sep 1;38(9):985-994. doi: 10.1097/EJA.0000000000001448. PMID: 34397527Free PMC Article
Zieliński J, Morawska-Kochman M, Zatoński T
Adv Clin Exp Med 2020 Mar;29(3):365-374. doi: 10.17219/acem/112600. PMID: 32129952
Frizzell KH, Cavanaugh PK, Herman MJ
Orthop Clin North Am 2017 Oct;48(4):467-480. Epub 2017 Aug 16 doi: 10.1016/j.ocl.2017.06.007. PMID: 28870306
Rawal N
Eur J Anaesthesiol 2016 Mar;33(3):160-71. doi: 10.1097/EJA.0000000000000366. PMID: 26509324
Lovich-Sapola J, Smith CE, Brandt CP
Surg Clin North Am 2015 Apr;95(2):301-18. Epub 2015 Jan 24 doi: 10.1016/j.suc.2014.10.002. PMID: 25814108

Therapy

Liu C, Chen X, Wu S
Complement Ther Med 2022 Dec;71:102892. Epub 2022 Oct 26 doi: 10.1016/j.ctim.2022.102892. PMID: 36309174
Boric K, Dosenovic S, Jelicic Kadic A, Batinic M, Cavar M, Urlic M, Markovina N, Puljak L
Paediatr Anaesth 2017 Sep;27(9):893-904. Epub 2017 Jul 14 doi: 10.1111/pan.13203. PMID: 28707454
Cheung CW, Ching Wong SS, Qiu Q, Wang X
Pain Physician 2017 Feb;20(2S):SE33-SE52. PMID: 28226340
Schwendicke F, Göstemeyer G
BMJ Open 2017 Feb 1;7(2):e013115. doi: 10.1136/bmjopen-2016-013115. PMID: 28148534Free PMC Article
Højer Karlsen AP, Geisler A, Petersen PL, Mathiesen O, Dahl JB
Pain 2015 Jan;156(1):8-30. doi: 10.1016/j.pain.0000000000000003. PMID: 25599296

Prognosis

Fahim MM, Saber SEM, Elkhatib WF, Nagy MM, Schafer E
Clin Oral Investig 2022 Feb;26(2):2155-2163. Epub 2021 Oct 25 doi: 10.1007/s00784-021-04196-w. PMID: 34697657
Yu YH, Kushnir L, Kohli M, Karabucak B
Clin Oral Investig 2021 Aug;25(8):5033-5042. Epub 2021 Feb 8 doi: 10.1007/s00784-021-03814-x. PMID: 33555456
Fregoso G, Wang A, Tseng K, Wang J
Pain Physician 2019 Sep;22(5):479-488. PMID: 31561647
Comparin D, Moreira EJL, Souza EM, De-Deus G, Arias A, Silva EJNL
J Endod 2017 Jul;43(7):1084-1088. Epub 2017 May 3 doi: 10.1016/j.joen.2017.02.010. PMID: 28477995
McNeely ML, Binkley JM, Pusic AL, Campbell KL, Gabram S, Soballe PW
Cancer 2012 Apr 15;118(8 Suppl):2226-36. doi: 10.1002/cncr.27468. PMID: 22488697

Clinical prediction guides

Sort R, Brorson S, Gögenur I, Hald LL, Nielsen JK, Salling N, Hougaard S, Foss NB, Tengberg PT, Klausen TW, Møller AM
Br J Anaesth 2021 Apr;126(4):881-888. Epub 2021 Feb 2 doi: 10.1016/j.bja.2020.12.037. PMID: 33546844
Velázquez-Saornil J, Ruíz-Ruíz B, Rodríguez-Sanz D, Romero-Morales C, López-López D, Calvo-Lobo C
Medicine (Baltimore) 2017 Apr;96(17):e6726. doi: 10.1097/MD.0000000000006726. PMID: 28445290Free PMC Article
Diener I, Kargela M, Louw A
Physiother Theory Pract 2016 Jul;32(5):356-67. Epub 2016 Jun 28 doi: 10.1080/09593985.2016.1194648. PMID: 27351690
Kerr D, Zhao W, Lurie JD
Clin Orthop Relat Res 2015 Jun;473(6):1920-30. doi: 10.1007/s11999-014-3803-7. PMID: 25057116Free PMC Article
Sharkey M
AAPS J 2013 Apr;15(2):598-607. Epub 2013 Mar 2 doi: 10.1208/s12248-013-9467-5. PMID: 23456420Free PMC Article

Recent systematic reviews

Xuan C, Yan W, Wang D, Li C, Ma H, Mueller A, Chin V, Houle TT, Wang J
Br J Anaesth 2022 Dec;129(6):946-958. Epub 2022 Oct 26 doi: 10.1016/j.bja.2022.08.038. PMID: 36404458
Lohsiriwat V, Jitmungngan R
Medicina (Kaunas) 2022 Mar 12;58(3) doi: 10.3390/medicina58030418. PMID: 35334594Free PMC Article
Waelkens P, Alsabbagh E, Sauter A, Joshi GP, Beloeil H; PROSPECT Working group∗∗ of the European Society of Regional Anaesthesia and Pain therapy (ESRA)
Eur J Anaesthesiol 2021 Sep 1;38(9):985-994. doi: 10.1097/EJA.0000000000001448. PMID: 34397527Free PMC Article
Anger M, Valovska T, Beloeil H, Lirk P, Joshi GP, Van de Velde M, Raeder J; PROSPECT Working Group* and the European Society of Regional Anaesthesia and Pain Therapy
Anaesthesia 2021 Aug;76(8):1082-1097. Epub 2021 May 20 doi: 10.1111/anae.15498. PMID: 34015859
Tola YO, Chow KM, Liang W
J Clin Nurs 2021 Dec;30(23-24):3369-3384. Epub 2021 May 3 doi: 10.1111/jocn.15827. PMID: 33942405

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