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Infective conjunctivitis

MedGen UID:
105421
•Concept ID:
C0497209
•
Disease or Syndrome
Synonym: Infectious Conjunctivitis
SNOMED CT: Infective conjunctivitis (299699004)

Definition

An infectious process affecting the conjunctiva. [from NCI]

Professional guidelines

PubMed

Acute infective conjunctivitis in primary care: who needs antibiotics? An individual patient data meta-analysis.
Jefferis J, Perera R, Everitt H, van Weert H, Rietveld R, Glasziou P, Rose P
Br J Gen Pract 2011 Sep;61(590):e542-8. doi: 10.3399/bjgp11X593811. PMID: 22152728Free PMC Article
Evidence-based treatment of acute infective conjunctivitis: Breaking the cycle of antibiotic prescribing.
Visscher KL, Hutnik CM, Thomas M
Can Fam Physician 2009 Nov;55(11):1071-5. PMID: 19910590Free PMC Article
Acute infective conjunctivitis: evidence review and management advice for New Zealand practitioners.
Oliver GF, Wilson GA, Everts RJ
N Z Med J 2009 Jul 3;122(1298):69-75. PMID: 19680306

Recent clinical studies

Etiology

A closed-loop audit of the prescription practice of topical antibiotics for acute infective conjunctivitis.
Katsimpris A, Voulgari N, Georgiadis N, Kandarakis S
Rom J Ophthalmol 2023 Jan-Mar;67(1):41-45. doi: 10.22336/rjo.2023.7. PMID: 37089795Free PMC Article
Effect of Topical Antibiotics on Duration of Acute Infective Conjunctivitis in Children: A Randomized Clinical Trial and a Systematic Review and Meta-analysis.
Honkila M, Koskela U, Kontiokari T, Mattila ML, Kristo A, Valtonen R, Sarlin S, Paalanne N, Ikäheimo I, Pokka T, Uhari M, Renko M, Tapiainen T
JAMA Netw Open 2022 Oct 3;5(10):e2234459. doi: 10.1001/jamanetworkopen.2022.34459. PMID: 36194412Free PMC Article
Antibiotic prescribing patterns of general practice registrars for infective conjunctivitis: a cross-sectional analysis.
Cherry MD, Tapley A, Quain D, Holliday EG, Ball J, Davey A, van Driel ML, Fielding A, Spike N, FitzGerald K, Magin P
J Prim Health Care 2021 Mar;13(1):5-14. doi: 10.1071/HC20040. PMID: 33785106
Bacterial conjunctivitis and of antibiotics in Dhulikhel Hospital-Kathmandu University Hospital.
Sthapit PR, Tuladhar NR, Marasini S, Khoju U, Thapa G
Kathmandu Univ Med J (KUMJ) 2011 Apr-Jun;9(34):69-72. doi: 10.3126/kumj.v9i2.6292. PMID: 22610873
Acute infective conjunctivitis in primary care: who needs antibiotics? An individual patient data meta-analysis.
Jefferis J, Perera R, Everitt H, van Weert H, Rietveld R, Glasziou P, Rose P
Br J Gen Pract 2011 Sep;61(590):e542-8. doi: 10.3399/bjgp11X593811. PMID: 22152728Free PMC Article

Diagnosis

Antibiotic prescribing patterns of general practice registrars for infective conjunctivitis: a cross-sectional analysis.
Cherry MD, Tapley A, Quain D, Holliday EG, Ball J, Davey A, van Driel ML, Fielding A, Spike N, FitzGerald K, Magin P
J Prim Health Care 2021 Mar;13(1):5-14. doi: 10.1071/HC20040. PMID: 33785106
Nursery sickness policies and their influence on prescribing for conjunctivitis: audit and questionnaire survey.
Finnikin S, Jolly K
Br J Gen Pract 2016 Sep;66(650):e674-9. Epub 2016 Jul 5 doi: 10.3399/bjgp16X686125. PMID: 27381485Free PMC Article
Evidence-based treatment of acute infective conjunctivitis: Breaking the cycle of antibiotic prescribing.
Visscher KL, Hutnik CM, Thomas M
Can Fam Physician 2009 Nov;55(11):1071-5. PMID: 19910590Free PMC Article
Acute infective conjunctivitis: evidence review and management advice for New Zealand practitioners.
Oliver GF, Wilson GA, Everts RJ
N Z Med J 2009 Jul 3;122(1298):69-75. PMID: 19680306
Management strategies for acute infective conjunctivitis in primary care: a systematic review.
Rose P
Expert Opin Pharmacother 2007 Aug;8(12):1903-21. doi: 10.1517/14656566.8.12.1903. PMID: 17696792

Therapy

Effect of Topical Antibiotics on Duration of Acute Infective Conjunctivitis in Children: A Randomized Clinical Trial and a Systematic Review and Meta-analysis.
Honkila M, Koskela U, Kontiokari T, Mattila ML, Kristo A, Valtonen R, Sarlin S, Paalanne N, Ikäheimo I, Pokka T, Uhari M, Renko M, Tapiainen T
JAMA Netw Open 2022 Oct 3;5(10):e2234459. doi: 10.1001/jamanetworkopen.2022.34459. PMID: 36194412Free PMC Article
Clarity and confidence in managing infective conjunctivitis.
Charles RC, Lim HK, Charles WN
J Prim Health Care 2021 Jun;13(2):121-123. doi: 10.1071/HC21042. PMID: 34620293
Acute infective conjunctivitis in primary care: who needs antibiotics? An individual patient data meta-analysis.
Jefferis J, Perera R, Everitt H, van Weert H, Rietveld R, Glasziou P, Rose P
Br J Gen Pract 2011 Sep;61(590):e542-8. doi: 10.3399/bjgp11X593811. PMID: 22152728Free PMC Article
Evidence-based treatment of acute infective conjunctivitis: Breaking the cycle of antibiotic prescribing.
Visscher KL, Hutnik CM, Thomas M
Can Fam Physician 2009 Nov;55(11):1071-5. PMID: 19910590Free PMC Article
Acute infective conjunctivitis: evidence review and management advice for New Zealand practitioners.
Oliver GF, Wilson GA, Everts RJ
N Z Med J 2009 Jul 3;122(1298):69-75. PMID: 19680306

Prognosis

Four cases of Raoultella planticola conjunctivitis.
Vassallo J, Vella M, Cassar R, Caruana P
Eye (Lond) 2016 Apr;30(4):632-4. Epub 2016 Jan 8 doi: 10.1038/eye.2015.260. PMID: 26742869Free PMC Article
Bacterial conjunctivitis and of antibiotics in Dhulikhel Hospital-Kathmandu University Hospital.
Sthapit PR, Tuladhar NR, Marasini S, Khoju U, Thapa G
Kathmandu Univ Med J (KUMJ) 2011 Apr-Jun;9(34):69-72. doi: 10.3126/kumj.v9i2.6292. PMID: 22610873
Acute infective conjunctivitis: evidence review and management advice for New Zealand practitioners.
Oliver GF, Wilson GA, Everts RJ
N Z Med J 2009 Jul 3;122(1298):69-75. PMID: 19680306
Sticky eye, tricky diagnosis.
Coote MA
Aust Fam Physician 2002 Mar;31(3):225-31. PMID: 11926153
Demand incidence and episode rates of ophthalmic disease in a defined urban population.
Sheldrick JH, Vernon SA, Wilson A, Read SJ
BMJ 1992 Oct 17;305(6859):933-6. doi: 10.1136/bmj.305.6859.933. PMID: 1458075Free PMC Article

Clinical prediction guides

Patient Perception and Emotional Disturbance in Out-of-Hour Ophthalmic Emergency Care.
Luk S, Stroman L, Kang S, Natkunarajah M, Duguid G
Semin Ophthalmol 2017;32(5):559-563. Epub 2016 Jun 21 doi: 10.3109/08820538.2015.1131834. PMID: 27328027
Relative impact of clinical evidence and over-the-counter prescribing on topical antibiotic use for acute infective conjunctivitis.
Davis H, Mant D, Scott C, Lasserson D, Rose PW
Br J Gen Pract 2009 Dec;59(569):897-900. doi: 10.3399/bjgp09X473132. PMID: 20875257Free PMC Article
Acute infective conjunctivitis: evidence review and management advice for New Zealand practitioners.
Oliver GF, Wilson GA, Everts RJ
N Z Med J 2009 Jul 3;122(1298):69-75. PMID: 19680306
Prevalence of refractive error and other eye diseases in schoolchildren in the Greater Accra region of Ghana.
Ntim-Amponsah CT, Ofosu-Amaah S
J Pediatr Ophthalmol Strabismus 2007 Sep-Oct;44(5):294-7. doi: 10.3928/01913913-20070901-04. PMID: 17913172
Causes and prevalence of non-vision impairing ocular conditions among a rural adult population in sw Uganda.
Kamali A, Whitworth JA, Ruberantwari A, Mulwanyi F, Acakara M, Dolin P, Johnson G
Ophthalmic Epidemiol 1999 Mar;6(1):41-8. doi: 10.1076/opep.6.1.41.1572. PMID: 10384683

Recent systematic reviews

Effect of Topical Antibiotics on Duration of Acute Infective Conjunctivitis in Children: A Randomized Clinical Trial and a Systematic Review and Meta-analysis.
Honkila M, Koskela U, Kontiokari T, Mattila ML, Kristo A, Valtonen R, Sarlin S, Paalanne N, Ikäheimo I, Pokka T, Uhari M, Renko M, Tapiainen T
JAMA Netw Open 2022 Oct 3;5(10):e2234459. doi: 10.1001/jamanetworkopen.2022.34459. PMID: 36194412Free PMC Article
Management strategies for acute infective conjunctivitis in primary care: a systematic review.
Rose P
Expert Opin Pharmacother 2007 Aug;8(12):1903-21. doi: 10.1517/14656566.8.12.1903. PMID: 17696792

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