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Osteoporotic femoral neck

MedGen UID:
1054405
•Concept ID:
CN377928
•
Finding
Synonym: Osteoporosis of femoral neck
 
HPO: HP:6000779

Definition

Low bone mass localized in the neck of the femur. Osteoporosis is defined based on a T-score of -2.5 or lower (bone mineral density of 2.5 or more standard deviations below that of a normal young adult). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOsteoporotic femoral neck

Professional guidelines

PubMed

Application of intelligent X-ray image analysis in risk assessment of osteoporotic fracture of femoral neck in the elderly.
Du J, Wang J, Gai X, Sui Y, Liu K, Yang D
Math Biosci Eng 2023 Jan;20(1):879-893. Epub 2022 Oct 18 doi: 10.3934/mbe.2023040. PMID: 36650793
Evaluation of calcaneal quantitative ultrasound in a primary care setting as a screening tool for osteoporosis in postmenopausal women.
Díez-Pérez A, Marín F, Vila J, Abizanda M, Cervera A, Carbonell C, Alcolea RM, Cama A, Rama T, Galindo E, Olmos C
J Clin Densitom 2003 Fall;6(3):237-45. doi: 10.1385/jcd:6:3:237. PMID: 14514993

Recent clinical studies

Etiology

Correlation between shape-closed femoral stem design and bone cement implantation syndrome in osteoporotic elderly femoral neck fracture undergoing cemented hip arthroplasty: A retrospective case-control study in 128 patients.
Chulsomlee K, Prukviwat S, Tuntiyatorn P, Vasaruchapong S, Kulachote N, Sirisreetreerux N, Tanphiriyakun T, Chanplakorn P, Sa-Ngasoongsong P
Orthop Traumatol Surg Res 2023 Feb;109(1):103450. Epub 2022 Oct 20 doi: 10.1016/j.otsr.2022.103450. PMID: 36273503
Neutrophil-lymphocyte ratio as a risk factor for osteoporotic vertebrae fractures and femoral neck fractures.
Zhu H, Li Z, Zhou Y, Zheng R, Diao C, Li K, Feng Q, Wang D
Medicine (Baltimore) 2022 Dec 2;101(48):e32125. doi: 10.1097/MD.0000000000032125. PMID: 36482639Free PMC Article
The Anti-osteoporosis Effects of Vitamin K in Postmenopausal Women.
Liu Y, He Y, He B, Kong L
Curr Stem Cell Res Ther 2022;17(2):186-192. doi: 10.2174/1574888X16666210512020103. PMID: 33982655
No Difference Between Hemiarthroplasty and Total Hip Arthroplasty in the Treatment of Pathologic Femoral Neck Fractures.
Hayden BL, Varady NH, Abdeen A, Lozano-Calderon SA, Chen AF, Ready JE; Pathologic Fracture Study Group
J Arthroplasty 2021 Nov;36(11):3662-3666. Epub 2021 Jul 29 doi: 10.1016/j.arth.2021.06.015. PMID: 34419316
Association between osteoporotic femoral neck fractures and DXA-derived 3D measurements at lumbar spine: a case-control study.
López Picazo M, Humbert L, Winzenrieth R, Di Gregorio S, González Ballester MA, Del Río Barquero LM
Arch Osteoporos 2020 Jan 3;15(1):8. doi: 10.1007/s11657-019-0680-4. PMID: 31897775

Diagnosis

Phosphaturic mesenchymal tumor-induced bilateral osteomalacia femoral neck fractures: a case report.
Zhang Y, Hu M, Guo C, Yang X, Xiang S, Xu H
Front Endocrinol (Lausanne) 2024;15:1373794. Epub 2024 Apr 16 doi: 10.3389/fendo.2024.1373794. PMID: 38689735Free PMC Article
Neutrophil-lymphocyte ratio as a risk factor for osteoporotic vertebrae fractures and femoral neck fractures.
Zhu H, Li Z, Zhou Y, Zheng R, Diao C, Li K, Feng Q, Wang D
Medicine (Baltimore) 2022 Dec 2;101(48):e32125. doi: 10.1097/MD.0000000000032125. PMID: 36482639Free PMC Article
No Difference Between Hemiarthroplasty and Total Hip Arthroplasty in the Treatment of Pathologic Femoral Neck Fractures.
Hayden BL, Varady NH, Abdeen A, Lozano-Calderon SA, Chen AF, Ready JE; Pathologic Fracture Study Group
J Arthroplasty 2021 Nov;36(11):3662-3666. Epub 2021 Jul 29 doi: 10.1016/j.arth.2021.06.015. PMID: 34419316
Screening osteoporotic femoral neck without measuring bone mineral density with the use of tartrate resistant acid phosphatase-5b and serum-creatinine-to-cystatin C ratio in Japanese postmenopausal women.
Yoshii I, Chijiwa T, Sawada N
J Orthop Sci 2020 Jul;25(4):671-676. Epub 2019 Jul 20 doi: 10.1016/j.jos.2019.07.002. PMID: 31337577
The importance of previous fracture site on osteoporosis diagnosis and incident fractures in women.
Morin SN, Lix LM, Leslie WD
J Bone Miner Res 2014 Jul;29(7):1675-80. doi: 10.1002/jbmr.2204. PMID: 24535832

Therapy

Correlation between shape-closed femoral stem design and bone cement implantation syndrome in osteoporotic elderly femoral neck fracture undergoing cemented hip arthroplasty: A retrospective case-control study in 128 patients.
Chulsomlee K, Prukviwat S, Tuntiyatorn P, Vasaruchapong S, Kulachote N, Sirisreetreerux N, Tanphiriyakun T, Chanplakorn P, Sa-Ngasoongsong P
Orthop Traumatol Surg Res 2023 Feb;109(1):103450. Epub 2022 Oct 20 doi: 10.1016/j.otsr.2022.103450. PMID: 36273503
The Anti-osteoporosis Effects of Vitamin K in Postmenopausal Women.
Liu Y, He Y, He B, Kong L
Curr Stem Cell Res Ther 2022;17(2):186-192. doi: 10.2174/1574888X16666210512020103. PMID: 33982655
No Difference Between Hemiarthroplasty and Total Hip Arthroplasty in the Treatment of Pathologic Femoral Neck Fractures.
Hayden BL, Varady NH, Abdeen A, Lozano-Calderon SA, Chen AF, Ready JE; Pathologic Fracture Study Group
J Arthroplasty 2021 Nov;36(11):3662-3666. Epub 2021 Jul 29 doi: 10.1016/j.arth.2021.06.015. PMID: 34419316
Intraoperative periarticular injection can alleviate the inflammatory response and enhance joint function recovery after hip arthroplasty in elderly patients with osteoporotic femoral neck fractures.
Xiong Z, Cao S, Zhou L, Zhang X, Liu Q, Hu J, Liu F, Li Y
Medicine (Baltimore) 2021 Feb 19;100(7):e24596. doi: 10.1097/MD.0000000000024596. PMID: 33607792Free PMC Article
Minimally invasive surgery for femoral neck fractures using bone cement infusible hollow-perforated screw in high-risk patients with advanced cancer.
Lin PP, Kang HG, Kim YI, Kim JH, Kim HS
Surg Oncol 2015 Sep;24(3):226-31. Epub 2015 May 22 doi: 10.1016/j.suronc.2015.05.003. PMID: 26051408

Prognosis

Correlation between shape-closed femoral stem design and bone cement implantation syndrome in osteoporotic elderly femoral neck fracture undergoing cemented hip arthroplasty: A retrospective case-control study in 128 patients.
Chulsomlee K, Prukviwat S, Tuntiyatorn P, Vasaruchapong S, Kulachote N, Sirisreetreerux N, Tanphiriyakun T, Chanplakorn P, Sa-Ngasoongsong P
Orthop Traumatol Surg Res 2023 Feb;109(1):103450. Epub 2022 Oct 20 doi: 10.1016/j.otsr.2022.103450. PMID: 36273503
In which patients does lumbar spine trabecular bone score (TBS) have the largest effect?
Martineau P, Leslie WD, Johansson H, Harvey NC, McCloskey EV, Hans D, Kanis JA
Bone 2018 Aug;113:161-168. Epub 2018 May 23 doi: 10.1016/j.bone.2018.05.026. PMID: 29802962Free PMC Article
Local Variation in Femoral Neck Cortical Bone: In Vitro Measured Bone Mineral Density, Geometry and Mechanical Properties.
Coutts LV, Jenkins T, Oreffo ROC, Dunlop DG, Cooper C, Harvey NC, Thurner PJ; OStEO Study Team
J Clin Densitom 2017 Apr-Jun;20(2):205-215. Epub 2015 Dec 23 doi: 10.1016/j.jocd.2015.10.003. PMID: 26710681
Association between low-frequency ultrasound and hip fractures -- comparison with DXA-based BMD.
Määttä M, Moilanen P, Timonen J, Pulkkinen P, Korpelainen R, Jämsä T
BMC Musculoskelet Disord 2014 Jun 16;15:208. doi: 10.1186/1471-2474-15-208. PMID: 24934318Free PMC Article
The importance of previous fracture site on osteoporosis diagnosis and incident fractures in women.
Morin SN, Lix LM, Leslie WD
J Bone Miner Res 2014 Jul;29(7):1675-80. doi: 10.1002/jbmr.2204. PMID: 24535832

Clinical prediction guides

Mechanical analysis of modified femoral neck system in the treatment of osteoporotic femoral neck fractures.
Nan C, Liu Y, Zhang D, Qin Y, Yu H, Liu Y, Ma Z
BMC Musculoskelet Disord 2024 Oct 4;25(1):789. doi: 10.1186/s12891-024-07907-y. PMID: 39367368Free PMC Article
Correlation between shape-closed femoral stem design and bone cement implantation syndrome in osteoporotic elderly femoral neck fracture undergoing cemented hip arthroplasty: A retrospective case-control study in 128 patients.
Chulsomlee K, Prukviwat S, Tuntiyatorn P, Vasaruchapong S, Kulachote N, Sirisreetreerux N, Tanphiriyakun T, Chanplakorn P, Sa-Ngasoongsong P
Orthop Traumatol Surg Res 2023 Feb;109(1):103450. Epub 2022 Oct 20 doi: 10.1016/j.otsr.2022.103450. PMID: 36273503
No Difference Between Hemiarthroplasty and Total Hip Arthroplasty in the Treatment of Pathologic Femoral Neck Fractures.
Hayden BL, Varady NH, Abdeen A, Lozano-Calderon SA, Chen AF, Ready JE; Pathologic Fracture Study Group
J Arthroplasty 2021 Nov;36(11):3662-3666. Epub 2021 Jul 29 doi: 10.1016/j.arth.2021.06.015. PMID: 34419316
Intraoperative periarticular injection can alleviate the inflammatory response and enhance joint function recovery after hip arthroplasty in elderly patients with osteoporotic femoral neck fractures.
Xiong Z, Cao S, Zhou L, Zhang X, Liu Q, Hu J, Liu F, Li Y
Medicine (Baltimore) 2021 Feb 19;100(7):e24596. doi: 10.1097/MD.0000000000024596. PMID: 33607792Free PMC Article
Association between osteoporotic femoral neck fractures and DXA-derived 3D measurements at lumbar spine: a case-control study.
López Picazo M, Humbert L, Winzenrieth R, Di Gregorio S, González Ballester MA, Del Río Barquero LM
Arch Osteoporos 2020 Jan 3;15(1):8. doi: 10.1007/s11657-019-0680-4. PMID: 31897775

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