U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal tissue enzyme concentration or activity

MedGen UID:
1054453
Concept ID:
CN376744
Finding
Synonym: Abnormal tissue enzyme activity
 
HPO: HP:6000231

Definition

Concentration of an enyzme in a tissue is above or between the limit of normal. This term is intended to be used for enzymes that can be measured in multiple tissues other than blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal tissue enzyme concentration or activity

Professional guidelines

PubMed

Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Succoio M, Sacchettini R, Rossi A, Parenti G, Ruoppolo M
Biomolecules 2022 Jul 11;12(7) doi: 10.3390/biom12070968. PMID: 35883524Free PMC Article
Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, Leontiadis GI, Abraham NS, Calvet X, Chan FKL, Douketis J, Enns R, Gralnek IM, Jairath V, Jensen D, Lau J, Lip GYH, Loffroy R, Maluf-Filho F, Meltzer AC, Reddy N, Saltzman JR, Marshall JK, Bardou M
Ann Intern Med 2019 Dec 3;171(11):805-822. Epub 2019 Oct 22 doi: 10.7326/M19-1795. PMID: 31634917Free PMC Article

Recent clinical studies

Etiology

Liang JH, Huang S, Pu YQ, Zhao Y, Chen YC, Jiang N, Liu ML, Bao WW, Zhang YS, Hu LX, Kakaer A, Huang SY, Pu XY, Chen YJ
J Affect Disord 2023 Nov 1;340:329-339. Epub 2023 Aug 4 doi: 10.1016/j.jad.2023.07.113. PMID: 37543116
Billinger SA, Arena R, Bernhardt J, Eng JJ, Franklin BA, Johnson CM, MacKay-Lyons M, Macko RF, Mead GE, Roth EJ, Shaughnessy M, Tang A; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Lifestyle and Cardiometabolic Health; Council on Epidemiology and Prevention; Council on Clinical Cardiology
Stroke 2014 Aug;45(8):2532-53. Epub 2014 May 20 doi: 10.1161/STR.0000000000000022. PMID: 24846875
González-Gross M, Meléndez A
Nutr Hosp 2013 Sep;28 Suppl 5:89-98. doi: 10.3305/nh.2013.28.sup5.6923. PMID: 24010748
Landry BW, Driscoll SW
PM R 2012 Nov;4(11):826-32. doi: 10.1016/j.pmrj.2012.09.585. PMID: 23174545
Tudor-Locke C, Bassett DR Jr
Sports Med 2004;34(1):1-8. doi: 10.2165/00007256-200434010-00001. PMID: 14715035

Diagnosis

Joshi PR, Zierz S
Molecules 2020 Apr 13;25(8) doi: 10.3390/molecules25081784. PMID: 32295037Free PMC Article
Wagner AH, Zaradzki M, Arif R, Remes A, Müller OJ, Kallenbach K
Biochem Pharmacol 2019 Jun;164:53-63. Epub 2019 Mar 27 doi: 10.1016/j.bcp.2019.03.034. PMID: 30926475
Kwok CS, Anderson SG, Myint PK, Mamas MA, Loke YK
Int J Cardiol 2014 Dec 15;177(2):467-76. Epub 2014 Sep 28 doi: 10.1016/j.ijcard.2014.09.104. PMID: 25443248
Perruchoud C, Buchser E, Johanek LM, Aminian K, Paraschiv-Ionescu A, Taylor RS
Neuromodulation 2014 Jun;17 Suppl 1:42-7. doi: 10.1111/ner.12036. PMID: 24974774
Bennell K, Dobson F, Hinman R
Arthritis Care Res (Hoboken) 2011 Nov;63 Suppl 11:S350-70. doi: 10.1002/acr.20538. PMID: 22588756

Therapy

Delgado J, Drinkwater EJ, Banyard HG, Haff GG, Nosaka K
J Strength Cond Res 2019 Oct;33(10):2595-2601. doi: 10.1519/JSC.0000000000003290. PMID: 31356511
Poyatos-León R, García-Hermoso A, Sanabria-Martínez G, Álvarez-Bueno C, Cavero-Redondo I, Martínez-Vizcaíno V
Birth 2017 Sep;44(3):200-208. Epub 2017 Jun 6 doi: 10.1111/birt.12294. PMID: 28589648
French B, Thomas LH, Coupe J, McMahon NE, Connell L, Harrison J, Sutton CJ, Tishkovskaya S, Watkins CL
Cochrane Database Syst Rev 2016 Nov 14;11(11):CD006073. doi: 10.1002/14651858.CD006073.pub3. PMID: 27841442Free PMC Article
O'Halloran PD, Blackstock F, Shields N, Holland A, Iles R, Kingsley M, Bernhardt J, Lannin N, Morris ME, Taylor NF
Clin Rehabil 2014 Dec;28(12):1159-71. Epub 2014 Jun 18 doi: 10.1177/0269215514536210. PMID: 24942478
Dobbins M, Husson H, DeCorby K, LaRocca RL
Cochrane Database Syst Rev 2013 Feb 28;2013(2):CD007651. doi: 10.1002/14651858.CD007651.pub2. PMID: 23450577Free PMC Article

Prognosis

Lee DH, Rezende LFM, Joh HK, Keum N, Ferrari G, Rey-Lopez JP, Rimm EB, Tabung FK, Giovannucci EL
Circulation 2022 Aug 16;146(7):523-534. Epub 2022 Jul 25 doi: 10.1161/CIRCULATIONAHA.121.058162. PMID: 35876019Free PMC Article
Chudasama YV, Khunti KK, Zaccardi F, Rowlands AV, Yates T, Gillies CL, Davies MJ, Dhalwani NN
BMC Med 2019 Jun 12;17(1):108. doi: 10.1186/s12916-019-1339-0. PMID: 31186007Free PMC Article
McTiernan A, Friedenreich CM, Katzmarzyk PT, Powell KE, Macko R, Buchner D, Pescatello LS, Bloodgood B, Tennant B, Vaux-Bjerke A, George SM, Troiano RP, Piercy KL; 2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*
Med Sci Sports Exerc 2019 Jun;51(6):1252-1261. doi: 10.1249/MSS.0000000000001937. PMID: 31095082Free PMC Article
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL
Intensive Care Med 2017 Feb;43(2):171-183. Epub 2016 Nov 18 doi: 10.1007/s00134-016-4612-0. PMID: 27864615
Biswas A, Oh PI, Faulkner GE, Bajaj RR, Silver MA, Mitchell MS, Alter DA
Ann Intern Med 2015 Jan 20;162(2):123-32. doi: 10.7326/M14-1651. PMID: 25599350

Clinical prediction guides

Fulk GD, He Y, Boyne P, Dunning K
Stroke 2017 Feb;48(2):406-411. Epub 2017 Jan 5 doi: 10.1161/STROKEAHA.116.015309. PMID: 28057807
Einspieler C, Peharz R, Marschik PB
J Pediatr (Rio J) 2016 May-Jun;92(3 Suppl 1):S64-70. Epub 2016 Mar 17 doi: 10.1016/j.jped.2015.12.003. PMID: 26997356
Voss C, Ogunleye AA, Sandercock GR
Pediatr Int 2013 Aug;55(4):498-507. Epub 2013 Jun 10 doi: 10.1111/ped.12092. PMID: 23461812
van Dongen JM, Proper KI, van Wier MF, van der Beek AJ, Bongers PM, van Mechelen W, van Tulder MW
Scand J Work Environ Health 2012 Sep;38(5):393-408. Epub 2012 Jan 24 doi: 10.5271/sjweh.3275. PMID: 22270562
Tyson S, Connell L
Clin Rehabil 2009 Nov;23(11):1018-33. Epub 2009 Sep 28 doi: 10.1177/0269215509339004. PMID: 19786420

Recent systematic reviews

Pojednic R, D'Arpino E, Halliday I, Bantham A
Int J Environ Res Public Health 2022 Apr 20;19(9) doi: 10.3390/ijerph19094981. PMID: 35564376Free PMC Article
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL
Intensive Care Med 2017 Feb;43(2):171-183. Epub 2016 Nov 18 doi: 10.1007/s00134-016-4612-0. PMID: 27864615
Aune D, Norat T, Leitzmann M, Tonstad S, Vatten LJ
Eur J Epidemiol 2015 Jul;30(7):529-42. Epub 2015 Jun 20 doi: 10.1007/s10654-015-0056-z. PMID: 26092138
Young MD, Plotnikoff RC, Collins CE, Callister R, Morgan PJ
Obes Rev 2014 Dec;15(12):983-95. Epub 2014 Oct 7 doi: 10.1111/obr.12225. PMID: 25428600
Teixeira PJ, Carraça EV, Markland D, Silva MN, Ryan RM
Int J Behav Nutr Phys Act 2012 Jun 22;9:78. doi: 10.1186/1479-5868-9-78. PMID: 22726453Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...