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Decreased urinary bile acid level

MedGen UID:
1054564
Concept ID:
CN376635
Finding
HPO: HP:6000126

Definition

The amount of bile acids in the urine, normalized for urine concentration, is below the lower limit of normal. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Dekker SEI, Bierau J, Giera M, Blomberg N, Drenth JPH, Mayboroda OA, de Fijter JW, Soonawala D; DIPAK Consortium
Eur J Clin Invest 2024 Apr;54(4):e14147. Epub 2023 Dec 9 doi: 10.1111/eci.14147. PMID: 38071418
Batta AK, Arora R, Salen G, Tint GS, Eskreis D, Katz S
J Lipid Res 1989 Dec;30(12):1953-62. PMID: 2621422

Recent clinical studies

Etiology

Botero Aguirre JP, Restrepo Hamid AM
Cochrane Database Syst Rev 2015 Nov 23;2015(11):CD010481. doi: 10.1002/14651858.CD010481.pub2. PMID: 26595825Free PMC Article
Tang YM, Wang JP, Bao WM, Yang JH, Ma LK, Yang J, Chen H, Xu Y, Yang LH, Li W, Zhu YP, Cheng JB
Int J Mol Med 2015 Aug;36(2):377-85. Epub 2015 Jun 3 doi: 10.3892/ijmm.2015.2233. PMID: 26046127Free PMC Article
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400
Strandvik B, Wahlén E, Wikström SA
Scand J Clin Lab Invest 1994 Feb;54(1):1-10. doi: 10.3109/00365519409086503. PMID: 8171265
Appel GB, Valeri A, Appel AS, Blum C
Am J Med 1989 Nov;87(5N):45N-50N. PMID: 2486547

Diagnosis

Heubi JE, Setchell KDR
J Pediatr Gastroenterol Nutr 2020 Apr;70(4):423-429. doi: 10.1097/MPG.0000000000002618. PMID: 31899729
Bajaj JS, Kakiyama G, Cox IJ, Nittono H, Takei H, White M, Fagan A, Gavis EA, Heuman DM, Gilles HC, Hylemon P, Taylor-Robinson SD, Legido-Quigley C, Kim M, Xu J, Williams R, Sikaroodi M, Pandak WM, Gillevet PM
Liver Transpl 2018 Jun;24(6):752-761. Epub 2018 May 13 doi: 10.1002/lt.25046. PMID: 29500907Free PMC Article
Thuijls G, van Wijck K, Grootjans J, Derikx JP, van Bijnen AA, Heineman E, Dejong CH, Buurman WA, Poeze M
Ann Surg 2011 Feb;253(2):303-8. doi: 10.1097/SLA.0b013e318207a767. PMID: 21245670
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400
Campbell CB, Cowen AE
Aust N Z J Med 1977 Dec;7(6):587-95. doi: 10.1111/j.1445-5994.1977.tb02313.x. PMID: 274937

Therapy

Heubi JE, Setchell KDR
J Pediatr Gastroenterol Nutr 2020 Apr;70(4):423-429. doi: 10.1097/MPG.0000000000002618. PMID: 31899729
Kim DJ, Chung H, Ji SC, Lee S, Yu KS, Jang IJ, Cho JY
Metabolomics 2019 Feb 27;15(3):30. doi: 10.1007/s11306-019-1494-5. PMID: 30830474
Wang XX, Edelstein MH, Gafter U, Qiu L, Luo Y, Dobrinskikh E, Lucia S, Adorini L, D'Agati VD, Levi J, Rosenberg A, Kopp JB, Gius DR, Saleem MA, Levi M
J Am Soc Nephrol 2016 May;27(5):1362-78. Epub 2015 Sep 30 doi: 10.1681/ASN.2014121271. PMID: 26424786Free PMC Article
Prandota J
Drugs 1988 May;35(5):542-78. doi: 10.2165/00003495-198835050-00004. PMID: 3293970
Campbell CB, Cowen AE
Aust N Z J Med 1977 Dec;7(6):587-95. doi: 10.1111/j.1445-5994.1977.tb02313.x. PMID: 274937

Prognosis

Huang L, Xu G, Zhang R, Wang Y, Ji J, Long F, Sun Y
Lipids Health Dis 2022 Jan 22;21(1):15. doi: 10.1186/s12944-021-01620-8. PMID: 35065639Free PMC Article
Bajaj JS, Kakiyama G, Cox IJ, Nittono H, Takei H, White M, Fagan A, Gavis EA, Heuman DM, Gilles HC, Hylemon P, Taylor-Robinson SD, Legido-Quigley C, Kim M, Xu J, Williams R, Sikaroodi M, Pandak WM, Gillevet PM
Liver Transpl 2018 Jun;24(6):752-761. Epub 2018 May 13 doi: 10.1002/lt.25046. PMID: 29500907Free PMC Article
Berg UB, Németh A
J Pediatr Gastroenterol Nutr 2018 Apr;66(4):575-580. doi: 10.1097/MPG.0000000000001862. PMID: 29240010
Lee CS, Kimura A, Wu JF, Ni YH, Hsu HY, Chang MH, Nittono H, Chen HL
J Lipid Res 2017 Mar;58(3):607-614. Epub 2017 Jan 10 doi: 10.1194/jlr.P070425. PMID: 28073941Free PMC Article
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400

Clinical prediction guides

Kim DJ, Chung H, Ji SC, Lee S, Yu KS, Jang IJ, Cho JY
Metabolomics 2019 Feb 27;15(3):30. doi: 10.1007/s11306-019-1494-5. PMID: 30830474
Bajaj JS, Kakiyama G, Cox IJ, Nittono H, Takei H, White M, Fagan A, Gavis EA, Heuman DM, Gilles HC, Hylemon P, Taylor-Robinson SD, Legido-Quigley C, Kim M, Xu J, Williams R, Sikaroodi M, Pandak WM, Gillevet PM
Liver Transpl 2018 Jun;24(6):752-761. Epub 2018 May 13 doi: 10.1002/lt.25046. PMID: 29500907Free PMC Article
Chu L, Zhang K, Zhang Y, Jin X, Jiang H
Int Urol Nephrol 2015 Feb;47(2):345-51. Epub 2014 Dec 25 doi: 10.1007/s11255-014-0901-0. PMID: 25539619
Reyes H, Sjövall J
Ann Med 2000 Mar;32(2):94-106. doi: 10.3109/07853890009011758. PMID: 10766400
Prandota J
Drugs 1988 May;35(5):542-78. doi: 10.2165/00003495-198835050-00004. PMID: 3293970

Recent systematic reviews

Botero Aguirre JP, Restrepo Hamid AM
Cochrane Database Syst Rev 2015 Nov 23;2015(11):CD010481. doi: 10.1002/14651858.CD010481.pub2. PMID: 26595825Free PMC Article

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