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Increased pulmonary capillary wedge pressure

MedGen UID:
105462
•Concept ID:
C0520850
•
Finding
Synonyms: High Pulmonary Arterial Wedge Pressure; Increased arterial wedge pressure; Increased pulmonary arterial wedge pressure; Increased pulmonary artery occlusion pressure
SNOMED CT: Increased pulmonary arterial wedge pressure (30261008); Increased pulmonary capillary wedge pressure (30261008); Increased arterial wedge pressure (30261008)
 
HPO: HP:0030876

Definition

Pulmonary capillary wedge pressure (PCWP) above 15mmHg. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased pulmonary capillary wedge pressure

Professional guidelines

PubMed

Effects of concentrated albumin treatment after aortocoronary bypass surgery.
Karanko MS, Laaksonen VO, Meretoja OA
Crit Care Med 1987 Aug;15(8):737-42. doi: 10.1097/00003246-198708000-00005. PMID: 3497011

Recent clinical studies

Etiology

Estimated pulmonary capillary wedge pressure assessed by speckle tracking echocardiography predicts successful ablation in paroxysmal atrial fibrillation.
Kawasaki M, Tanaka R, Miyake T, Matsuoka R, Kaneda M, Minatoguchi S, Hirose T, Ono K, Nagaya M, Sato H, Kawase Y, Tomita S, Tsuchiya K, Matsuo H, Noda T, Minatoguchi S
Cardiovasc Ultrasound 2016 Jan 27;14:6. doi: 10.1186/s12947-016-0049-4. PMID: 26817595Free PMC Article
Obesity is associated with lower coronary microvascular density.
Campbell DJ, Somaratne JB, Prior DL, Yii M, Kenny JF, Newcomb AE, Kelly DJ, Black MJ
PLoS One 2013;8(11):e81798. Epub 2013 Nov 29 doi: 10.1371/journal.pone.0081798. PMID: 24312359Free PMC Article
Pressure reflection in the pulmonary circulation by echocardiography in patients with left heart disease indicates reactive pulmonary hypertension.
Bech-Hanssen O, Fadel B, Al Habeeb W, Al Buraiki J, Selimovic N
Int J Cardiol 2013 Oct 9;168(4):4222-7. Epub 2013 Aug 6 doi: 10.1016/j.ijcard.2013.07.153. PMID: 23932041
Diastolic heart dysfunction, increased pulmonary capillary wedge pressure and impaired exercise tolerance in patients with systemic sclerosis.
Płazak W, Gryga K, Sznajd J, Tomkiewicz-Pająk L, Suchoń E, Wilisowska J, Musiał J, Podolec P
Kardiol Pol 2011;69(3):243-9. PMID: 21432793
Amniotic fluid embolism.
Green BT, Umana E
South Med J 2000 Jul;93(7):721-3. PMID: 10923965

Diagnosis

Estimated pulmonary capillary wedge pressure assessed by speckle tracking echocardiography predicts successful ablation in paroxysmal atrial fibrillation.
Kawasaki M, Tanaka R, Miyake T, Matsuoka R, Kaneda M, Minatoguchi S, Hirose T, Ono K, Nagaya M, Sato H, Kawase Y, Tomita S, Tsuchiya K, Matsuo H, Noda T, Minatoguchi S
Cardiovasc Ultrasound 2016 Jan 27;14:6. doi: 10.1186/s12947-016-0049-4. PMID: 26817595Free PMC Article
Pressure reflection in the pulmonary circulation by echocardiography in patients with left heart disease indicates reactive pulmonary hypertension.
Bech-Hanssen O, Fadel B, Al Habeeb W, Al Buraiki J, Selimovic N
Int J Cardiol 2013 Oct 9;168(4):4222-7. Epub 2013 Aug 6 doi: 10.1016/j.ijcard.2013.07.153. PMID: 23932041
Diastolic heart dysfunction, increased pulmonary capillary wedge pressure and impaired exercise tolerance in patients with systemic sclerosis.
Płazak W, Gryga K, Sznajd J, Tomkiewicz-Pająk L, Suchoń E, Wilisowska J, Musiał J, Podolec P
Kardiol Pol 2011;69(3):243-9. PMID: 21432793
Usefulness of hand-carried ultrasound to predict elevated left ventricular filling pressure.
Blair JE, Brennan JM, Goonewardena SN, Shah D, Vasaiwala S, Spencer KT
Am J Cardiol 2009 Jan 15;103(2):246-7. Epub 2008 Oct 30 doi: 10.1016/j.amjcard.2008.08.061. PMID: 19121445
Amniotic fluid embolism.
Green BT, Umana E
South Med J 2000 Jul;93(7):721-3. PMID: 10923965

Therapy

Hemodynamic Response to Rapid Saline Infusion Compared with Exercise in Healthy Participants Aged 20-80 Years.
Andersen MJ, Wolsk E, Bakkestrøm R, Thomsen JH, Balling L, Dahl JS, Gustafsson F, Møller JE, Hassager C
J Card Fail 2019 Nov;25(11):902-910. Epub 2019 Jun 17 doi: 10.1016/j.cardfail.2019.06.004. PMID: 31220623
Estimated pulmonary capillary wedge pressure assessed by speckle tracking echocardiography predicts successful ablation in paroxysmal atrial fibrillation.
Kawasaki M, Tanaka R, Miyake T, Matsuoka R, Kaneda M, Minatoguchi S, Hirose T, Ono K, Nagaya M, Sato H, Kawase Y, Tomita S, Tsuchiya K, Matsuo H, Noda T, Minatoguchi S
Cardiovasc Ultrasound 2016 Jan 27;14:6. doi: 10.1186/s12947-016-0049-4. PMID: 26817595Free PMC Article
Hemodynamic effects of supplemental oxygen administration in congestive heart failure.
Haque WA, Boehmer J, Clemson BS, Leuenberger UA, Silber DH, Sinoway LI
J Am Coll Cardiol 1996 Feb;27(2):353-7. doi: 10.1016/0735-1097(95)00474-2. PMID: 8557905
Cardiac dysfunction and pulmonary edema following scorpion envenomation.
Abroug F, Boujdaria R, Belghith M, Nouira S, Bouchoucha S
Chest 1991 Oct;100(4):1057-9. doi: 10.1378/chest.100.4.1057. PMID: 1914557
Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosis. A prospective, controlled clinical study.
Cooper DJ, Walley KR, Wiggs BR, Russell JA
Ann Intern Med 1990 Apr 1;112(7):492-8. doi: 10.7326/0003-4819-112-7-492. PMID: 2156475

Prognosis

Estimated pulmonary capillary wedge pressure assessed by speckle tracking echocardiography predicts successful ablation in paroxysmal atrial fibrillation.
Kawasaki M, Tanaka R, Miyake T, Matsuoka R, Kaneda M, Minatoguchi S, Hirose T, Ono K, Nagaya M, Sato H, Kawase Y, Tomita S, Tsuchiya K, Matsuo H, Noda T, Minatoguchi S
Cardiovasc Ultrasound 2016 Jan 27;14:6. doi: 10.1186/s12947-016-0049-4. PMID: 26817595Free PMC Article
Relationships between biomarkers and left ventricular filling pressures at rest and during exercise in patients after myocardial infarction.
Andersen MJ, Ersbøll M, Bro-Jeppesen J, Møller JE, Hassager C, Køber L, Borlaug BA, Goetze JP, Gustafsson F
J Card Fail 2014 Dec;20(12):959-67. Epub 2014 Oct 5 doi: 10.1016/j.cardfail.2014.09.012. PMID: 25285749
Diastolic heart dysfunction, increased pulmonary capillary wedge pressure and impaired exercise tolerance in patients with systemic sclerosis.
Płazak W, Gryga K, Sznajd J, Tomkiewicz-Pająk L, Suchoń E, Wilisowska J, Musiał J, Podolec P
Kardiol Pol 2011;69(3):243-9. PMID: 21432793
Usefulness of hand-carried ultrasound to predict elevated left ventricular filling pressure.
Blair JE, Brennan JM, Goonewardena SN, Shah D, Vasaiwala S, Spencer KT
Am J Cardiol 2009 Jan 15;103(2):246-7. Epub 2008 Oct 30 doi: 10.1016/j.amjcard.2008.08.061. PMID: 19121445
Amniotic fluid embolism.
Green BT, Umana E
South Med J 2000 Jul;93(7):721-3. PMID: 10923965

Clinical prediction guides

Estimated pulmonary capillary wedge pressure assessed by speckle tracking echocardiography predicts successful ablation in paroxysmal atrial fibrillation.
Kawasaki M, Tanaka R, Miyake T, Matsuoka R, Kaneda M, Minatoguchi S, Hirose T, Ono K, Nagaya M, Sato H, Kawase Y, Tomita S, Tsuchiya K, Matsuo H, Noda T, Minatoguchi S
Cardiovasc Ultrasound 2016 Jan 27;14:6. doi: 10.1186/s12947-016-0049-4. PMID: 26817595Free PMC Article
Relationships between biomarkers and left ventricular filling pressures at rest and during exercise in patients after myocardial infarction.
Andersen MJ, Ersbøll M, Bro-Jeppesen J, Møller JE, Hassager C, Køber L, Borlaug BA, Goetze JP, Gustafsson F
J Card Fail 2014 Dec;20(12):959-67. Epub 2014 Oct 5 doi: 10.1016/j.cardfail.2014.09.012. PMID: 25285749
Usefulness of hand-carried ultrasound to predict elevated left ventricular filling pressure.
Blair JE, Brennan JM, Goonewardena SN, Shah D, Vasaiwala S, Spencer KT
Am J Cardiol 2009 Jan 15;103(2):246-7. Epub 2008 Oct 30 doi: 10.1016/j.amjcard.2008.08.061. PMID: 19121445
QT dispersion in nonischemic dilated cardiomyopathy. A long-term evaluation.
Fauchier L, Douglas J, Babuty D, Cosnay P, Fauchier JP
Eur J Heart Fail 2005 Mar 2;7(2):277-82. doi: 10.1016/j.ejheart.2004.07.009. PMID: 15701478
Interventricular and intraventricular dyssynchrony in idiopathic dilated cardiomyopathy: a prognostic study with fourier phase analysis of radionuclide angioscintigraphy.
Fauchier L, Marie O, Casset-Senon D, Babuty D, Cosnay P, Fauchier JP
J Am Coll Cardiol 2002 Dec 4;40(11):2022-30. doi: 10.1016/s0735-1097(02)02569-x. PMID: 12475464

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