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Epilepsy, early-onset

MedGen UID:
1054723
Concept ID:
CN376792
Disease or Syndrome
Synonym: epilepsy, early-onset
 
Monarch Initiative: MONDO:0957599
OMIM® Phenotypic series: PS617290

Professional guidelines

PubMed

Haviland I, Daniels CI, Greene CA, Drew J, Love-Nichols JA, Swanson LC, Smith L, Nie DA, Benke T, Sheidley BR, Zhang B, Poduri A, Olson HE
Pediatr Neurol 2023 Jan;138:71-80. Epub 2022 Oct 26 doi: 10.1016/j.pediatrneurol.2022.10.006. PMID: 36403551Free PMC Article
Nabavi Nouri M, Zak M, Jain P, Whitney R
Pediatr Neurol 2022 Jan;126:11-19. Epub 2021 Sep 30 doi: 10.1016/j.pediatrneurol.2021.09.017. PMID: 34740132
Bayat A, Bayat M, Rubboli G, Møller RS
Genes (Basel) 2021 Jul 8;12(7) doi: 10.3390/genes12071051. PMID: 34356067Free PMC Article

Recent clinical studies

Etiology

Putaala J
Continuum (Minneap Minn) 2020 Apr;26(2):386-414. doi: 10.1212/CON.0000000000000833. PMID: 32224758
Hedrich UBS, Lauxmann S, Lerche H
Epilepsia 2019 Dec;60 Suppl 3:S68-S76. doi: 10.1111/epi.14731. PMID: 31904120
Wong-Kisiel LC, Blauwblomme T, Ho ML, Boddaert N, Parisi J, Wirrell E, Nabbout R
Epilepsy Res 2018 Sep;145:1-17. Epub 2018 May 14 doi: 10.1016/j.eplepsyres.2018.05.006. PMID: 29803953
Helbig I, von Deimling M, Marsh ED
Adv Neurobiol 2017;15:295-315. doi: 10.1007/978-3-319-57193-5_11. PMID: 28674986
Cross JH, Guerrini R
Handb Clin Neurol 2013;111:619-26. doi: 10.1016/B978-0-444-52891-9.00064-6. PMID: 23622209

Diagnosis

Leonard H, Downs J, Benke TA, Swanson L, Olson H, Demarest S
Lancet Neurol 2022 Jun;21(6):563-576. Epub 2022 Apr 25 doi: 10.1016/S1474-4422(22)00035-7. PMID: 35483386Free PMC Article
Scheffer IE, Nabbout R
Epilepsia 2019 Dec;60 Suppl 3:S17-S24. doi: 10.1111/epi.16386. PMID: 31904117
Pisani F, Percesepe A, Spagnoli C
Eur J Paediatr Neurol 2018 May;22(3):354-357. Epub 2018 Feb 16 doi: 10.1016/j.ejpn.2018.02.006. PMID: 29501409
von Deimling M, Helbig I, Marsh ED
Curr Neurol Neurosci Rep 2017 Feb;17(2):10. doi: 10.1007/s11910-017-0720-7. PMID: 28229394
Cross JH, Guerrini R
Handb Clin Neurol 2013;111:619-26. doi: 10.1016/B978-0-444-52891-9.00064-6. PMID: 23622209

Therapy

Phan J, Ramos M, Soares T, Parmar MS
Oxid Med Cell Longev 2022;2022:7692215. Epub 2022 Oct 26 doi: 10.1155/2022/7692215. PMID: 36338344Free PMC Article
Golub V, Reddy DS
Adv Exp Med Biol 2021;1264:93-110. doi: 10.1007/978-3-030-57369-0_7. PMID: 33332006
Wilson MP, Plecko B, Mills PB, Clayton PT
J Inherit Metab Dis 2019 Jul;42(4):629-646. Epub 2019 Mar 20 doi: 10.1002/jimd.12060. PMID: 30671974
Varelas PN, Spanaki MV, Mirski MA
Neurosurg Clin N Am 2013 Jul;24(3):393-406. Epub 2013 Apr 29 doi: 10.1016/j.nec.2013.03.005. PMID: 23809033
Pearl PL, Bennett HD, Khademian Z
Curr Neurol Neurosci Rep 2005 Mar;5(2):127-33. doi: 10.1007/s11910-005-0010-7. PMID: 15743550

Prognosis

Steel D, Kurian MA
Curr Opin Neurol 2020 Aug;33(4):500-507. doi: 10.1097/WCO.0000000000000831. PMID: 32657892
Putaala J
Continuum (Minneap Minn) 2020 Apr;26(2):386-414. doi: 10.1212/CON.0000000000000833. PMID: 32224758
Wong-Kisiel LC, Blauwblomme T, Ho ML, Boddaert N, Parisi J, Wirrell E, Nabbout R
Epilepsy Res 2018 Sep;145:1-17. Epub 2018 May 14 doi: 10.1016/j.eplepsyres.2018.05.006. PMID: 29803953
Noebels J
J Gen Physiol 2017 May 1;149(5):533-546. Epub 2017 Apr 20 doi: 10.1085/jgp.201711759. PMID: 28428202Free PMC Article
Dibbens LM, Rubboli G
Epileptic Disord 2016 Sep 1;18(S2):111-114. doi: 10.1684/epd.2016.0848. PMID: 27618868

Clinical prediction guides

Zhu ZA, Li YY, Xu J, Xue H, Feng X, Zhu YC, Xiong ZQ
Cell Rep 2023 Oct 31;42(10):113202. Epub 2023 Sep 30 doi: 10.1016/j.celrep.2023.113202. PMID: 37777961
Langhammer F, Maroofian R, Badar R, Gregor A, Rochman M, Ratliff JB, Koopmans M, Herget T, Hempel M, Kortüm F, Heron D, Mignot C, Keren B, Brooks S, Botti C, Ben-Zeev B, Argilli E, Sherr EH, Gowda VK, Srinivasan VM, Bakhtiari S, Kruer MC, Salih MA, Kuechler A, Muller EA, Blocker K, Kuismin O, Park KL, Kochhar A, Brown K, Ramanathan S, Clark RD, Elgizouli M, Melikishvili G, Tabatadze N, Stark Z, Mirzaa GM, Ong J, Grasshoff U, Bevot A, von Wintzingerode L, Jamra RA, Hennig Y, Goldenberg P, Al Alam C, Charif M, Boulouiz R, Bellaoui M, Amrani R, Al Mutairi F, Tamim AM, Abdulwahab F, Alkuraya FS, Khouj EM, Alvi JR, Sultan T, Hashemi N, Karimiani EG, Ashrafzadeh F, Imannezhad S, Efthymiou S, Houlden H, Sticht H, Zweier C
Genet Med 2023 Aug;25(8):100885. Epub 2023 May 8 doi: 10.1016/j.gim.2023.100885. PMID: 37165955
Talwar D, Hammer MF
Pediatr Neurol 2021 Sep;122:76-83. Epub 2021 Aug 3 doi: 10.1016/j.pediatrneurol.2021.06.011. PMID: 34353676
Itai T, Miyatake S, Taguri M, Nozaki F, Ohta M, Osaka H, Morimoto M, Tandou T, Nohara F, Takami Y, Yoshioka F, Shimokawa S, Okuno-Yuguchi J, Motobayashi M, Takei Y, Fukuyama T, Kumada S, Miyata Y, Ogawa C, Maki Y, Togashi N, Ishikura T, Kinoshita M, Mitani Y, Kanemura Y, Omi T, Ando N, Hattori A, Saitoh S, Kitai Y, Hirai S, Arai H, Ishida F, Taniguchi H, Kitabatake Y, Ozono K, Nabatame S, Smigiel R, Kato M, Tanda K, Saito Y, Ishiyama A, Noguchi Y, Miura M, Nakano T, Hirano K, Honda R, Kuki I, Takanashi JI, Takeuchi A, Fukasawa T, Seiwa C, Harada A, Yachi Y, Higashiyama H, Terashima H, Kumagai T, Hada S, Abe Y, Miyagi E, Uchiyama Y, Fujita A, Imagawa E, Azuma Y, Hamanaka K, Koshimizu E, Mitsuhashi S, Mizuguchi T, Takata A, Miyake N, Tsurusaki Y, Doi H, Nakashima M, Saitsu H, Matsumoto N
J Med Genet 2021 Aug;58(8):505-513. Epub 2020 Jul 30 doi: 10.1136/jmedgenet-2020-106896. PMID: 32732225
Inuzuka LM, Macedo-Souza LI, Della-Rippa B, Monteiro FP, Delgado DS, Godoy LF, Ramos L, de Athayde Costa LS, Garzon E, Kok F
Epileptic Disord 2020 Jun 1;22(3):317-322. doi: 10.1684/epd.2020.1166. PMID: 32597767

Recent systematic reviews

Vignatelli L, Tontini V, Meletti S, Camerlingo M, Mazzoni S, Giovannini G, Pasini E, Michelucci R, Bisulli F, Tinuper P, Di Vito L
Epilepsia 2024 Jun;65(6):1512-1530. Epub 2024 Apr 12 doi: 10.1111/epi.17982. PMID: 38606469
Chen L, Yang W, Yang F, Yu Y, Xu T, Wang D, Zhao Q, Wu Q, Han Y
Epilepsy Behav 2024 Mar;152:109640. Epub 2024 Jan 31 doi: 10.1016/j.yebeh.2024.109640. PMID: 38301455
Falsaperla R, Scalia B, Giugno A, Pavone P, Motta M, Caccamo M, Ruggieri M
Ital J Pediatr 2021 Apr 7;47(1):85. doi: 10.1186/s13052-021-01027-2. PMID: 33827647Free PMC Article
Stefanski A, Calle-López Y, Leu C, Pérez-Palma E, Pestana-Knight E, Lal D
Epilepsia 2021 Jan;62(1):143-151. Epub 2020 Nov 17 doi: 10.1111/epi.16755. PMID: 33200402Free PMC Article
Nevin SM, Wakefield CE, Schilstra CE, McGill BC, Bye A, Palmer EE
Epilepsy Behav 2020 Nov;112:107382. Epub 2020 Aug 24 doi: 10.1016/j.yebeh.2020.107382. PMID: 32854014

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