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Hepatitis C, Chronic

MedGen UID:
105623
Concept ID:
C0524910
Disease or Syndrome
Synonym: Chronic Hepatitis C
SNOMED CT: Chronic type C viral hepatitis (128302006); Chronic hepatitis C (128302006)

Definition

INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatitis C, Chronic

Professional guidelines

PubMed

Abu-Freha N, Mathew Jacob B, Elhoashla A, Afawi Z, Abu-Hammad T, Elsana F, Paz S, Etzion O
Eur J Gen Pract 2022 Dec;28(1):102-108. doi: 10.1080/13814788.2022.2056161. PMID: 35579223Free PMC Article
Lanini S, Ustianowski A, Pisapia R, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):1045-1062. doi: 10.1016/j.idc.2019.08.004. PMID: 31668190
Zeuzem S
Dtsch Arztebl Int 2017 Jan 9;114(1-02):11-21. doi: 10.3238/arztebl.2017.0011. PMID: 28143635Free PMC Article

Recent clinical studies

Etiology

El-Kassas M, Awad A
World J Gastroenterol 2022 Jun 14;28(22):2429-2436. doi: 10.3748/wjg.v28.i22.2429. PMID: 35979265Free PMC Article
Massoud O
Expert Rev Gastroenterol Hepatol 2020 May;14(5):367-374. Epub 2020 Mar 27 doi: 10.1080/17474124.2020.1746641. PMID: 32216467
Mysore KR, Leung DH
Clin Liver Dis 2018 Nov;22(4):703-722. Epub 2018 Aug 22 doi: 10.1016/j.cld.2018.06.002. PMID: 30266158
Mekov EV, Petkov RE, Kostadinov DT, Antonov KA, Jelev DT
Folia Med (Plovdiv) 2017 Jun 1;59(2):132-138. doi: 10.1515/folmed-2017-0018. PMID: 28704182
Macías J, Vispo E, Pineda JA, Soriano V
Curr Opin HIV AIDS 2011 Nov;6(6):491-500. doi: 10.1097/COH.0b013e32834bca2d. PMID: 21918436

Diagnosis

Ghany MG, Morgan TR; AASLD-IDSA Hepatitis C Guidance Panel
Hepatology 2020 Feb;71(2):686-721. doi: 10.1002/hep.31060. PMID: 31816111Free PMC Article
Mysore KR, Leung DH
Clin Liver Dis 2018 Nov;22(4):703-722. Epub 2018 Aug 22 doi: 10.1016/j.cld.2018.06.002. PMID: 30266158
Kusari A, Ahluwalia J
N Engl J Med 2018 Aug 9;379(6):567. doi: 10.1056/NEJMicm1802078. PMID: 30089065
Westerhoff M, Ahn J
Surg Pathol Clin 2018 Jun;11(2):287-296. Epub 2018 Mar 26 doi: 10.1016/j.path.2018.02.002. PMID: 29751875
Sebastiani G, Gkouvatsos K, Pantopoulos K
World J Gastroenterol 2014 Aug 28;20(32):11033-53. doi: 10.3748/wjg.v20.i32.11033. PMID: 25170193Free PMC Article

Therapy

Jakobsen JC, Nielsen EE, Feinberg J, Katakam KK, Fobian K, Hauser G, Poropat G, Djurisic S, Weiss KH, Bjelakovic M, Bjelakovic G, Klingenberg SL, Liu JP, Nikolova D, Koretz RL, Gluud C
Cochrane Database Syst Rev 2017 Sep 18;9(9):CD012143. doi: 10.1002/14651858.CD012143.pub3. PMID: 28922704Free PMC Article
Jakobsen JC, Nielsen EE, Feinberg J, Katakam KK, Fobian K, Hauser G, Poropat G, Djurisic S, Weiss KH, Bjelakovic M, Bjelakovic G, Klingenberg SL, Liu JP, Nikolova D, Koretz RL, Gluud C
Cochrane Database Syst Rev 2017 Jun 6;6(6):CD012143. doi: 10.1002/14651858.CD012143.pub2. PMID: 28585310Free PMC Article
Tang L, Ward H, Kattakuzhy S, Wilson E, Kottilil S
Expert Rev Gastroenterol Hepatol 2016;10(1):21-36. Epub 2015 Dec 11 doi: 10.1586/17474124.2016.1119042. PMID: 26558305
Childs-Kean LM, Hand EO
Clin Ther 2015 Feb 1;37(2):243-67. Epub 2015 Jan 16 doi: 10.1016/j.clinthera.2014.12.012. PMID: 25601269
Rzouq F, Alahdab F, Olyaee M
Am J Med Sci 2014 Nov;348(5):426-30. doi: 10.1097/MAJ.0000000000000291. PMID: 24805786

Prognosis

Paik JM, Golabi P, Younossi Y, Mishra A, Younossi ZM
Hepatology 2020 Nov;72(5):1605-1616. Epub 2020 Oct 27 doi: 10.1002/hep.31173. PMID: 32043613
Simoncini GM, Koren DE
J Am Board Fam Med 2019 May-Jun;32(3):428-430. doi: 10.3122/jabfm.2019.03.180286. PMID: 31068409
Wu T, Konyn PG, Cattaneo AW, Saab S
Dig Dis Sci 2019 Jul;64(7):1782-1788. Epub 2019 Feb 13 doi: 10.1007/s10620-019-05511-y. PMID: 30756208
Bedimo R, Maalouf NM, Lo Re V 3rd
Curr Opin HIV AIDS 2016 May;11(3):285-93. doi: 10.1097/COH.0000000000000259. PMID: 26890206Free PMC Article
Rodríguez-Torres M
Clin Gastroenterol Hepatol 2008 May;6(5):484-90. doi: 10.1016/j.cgh.2008.02.036. PMID: 18455693

Clinical prediction guides

Valva P, Ríos DA, De Matteo E, Preciado MV
World J Gastroenterol 2016 Jan 28;22(4):1367-81. doi: 10.3748/wjg.v22.i4.1367. PMID: 26819506Free PMC Article
Dhingra S, Ward SC, Thung SN
World J Gastroenterol 2016 Jan 28;22(4):1357-66. doi: 10.3748/wjg.v22.i4.1357. PMID: 26819505Free PMC Article
Guido M, Mangia A, Faa G; Gruppo Italiano Patologi Apparato Digerente (GIPAD); Società Italiana di Anatomia Patologica e Citopatologia Diagnostica/International Academy of Pathology, Italian division (SIAPEC/IAP)
Dig Liver Dis 2011 Mar;43 Suppl 4:S331-43. doi: 10.1016/S1590-8658(11)60589-6. PMID: 21459339
Kleiner DE
Semin Liver Dis 2005 Feb;25(1):52-64. doi: 10.1055/s-2005-864781. PMID: 15731997
Wai CT, Greenson JK, Fontana RJ, Kalbfleisch JD, Marrero JA, Conjeevaram HS, Lok AS
Hepatology 2003 Aug;38(2):518-26. doi: 10.1053/jhep.2003.50346. PMID: 12883497

Recent systematic reviews

Paik JM, Golabi P, Younossi Y, Mishra A, Younossi ZM
Hepatology 2020 Nov;72(5):1605-1616. Epub 2020 Oct 27 doi: 10.1002/hep.31173. PMID: 32043613
Jakobsen JC, Nielsen EE, Feinberg J, Katakam KK, Fobian K, Hauser G, Poropat G, Djurisic S, Weiss KH, Bjelakovic M, Bjelakovic G, Klingenberg SL, Liu JP, Nikolova D, Koretz RL, Gluud C
Cochrane Database Syst Rev 2017 Jun 6;6(6):CD012143. doi: 10.1002/14651858.CD012143.pub2. PMID: 28585310Free PMC Article
Polaris Observatory HCV Collaborators
Lancet Gastroenterol Hepatol 2017 Mar;2(3):161-176. Epub 2016 Dec 16 doi: 10.1016/S2468-1253(16)30181-9. PMID: 28404132
Olubamwo OO, Aregbesola AO, Miettola J, Kauhanen J, Tuomainen TP
Public Health 2016 Sep;138:12-25. Epub 2016 May 18 doi: 10.1016/j.puhe.2016.04.005. PMID: 27207725
Mohsen A, Norris S
BMJ Clin Evid 2010 Feb 3;2010 PMID: 21718581Free PMC Article

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