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Ocular melanoma

MedGen UID:
107846
Concept ID:
C0558356
Neoplastic Process
Synonyms: Eye Melanoma; eye melanoma; eye melanoma (disease); eyeball of camera-type eye melanoma; eyeball of camera-type eye melanoma (disease); Malignant melanoma of eye; melanoma (disease) of eyeball of camera-type eye; Melanoma of Eye; melanoma of eye; Melanoma of the Eye; melanoma of the eye; MM (malignant melanoma) of eye; Ocular Melanoma; ocular melanoma; OM
SNOMED CT: Malignant melanoma of eye (274087000); Ocular melanoma (274087000); MM (malignant melanoma) of eye (274087000)
 
Monarch Initiative: MONDO:0006325

Definition

A melanoma that arises from the structures of the eye or ocular adnexa. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOcular melanoma

Professional guidelines

PubMed

Weis E, Surgeoner B, Salopek TG, Cheng T, Hyrcza M, Kostaras X, Larocque M, McKinnon G, McWhae J, Menon G, Monzon J, Murtha AD, Walker J, Temple-Oberle C
Curr Oncol 2023 Dec 20;31(1):24-41. doi: 10.3390/curroncol31010002. PMID: 38275828Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Blum ES, Yang J, Komatsubara KM, Carvajal RD
Oncology (Williston Park) 2016 Jan;30(1):29-32, 34-43, 48. PMID: 26791842

Recent clinical studies

Etiology

Gu X, Zhuang A, Yu J, Yang L, Ge S, Ruan J, Jia R, Fan X, Chai P
Nucleic Acids Res 2024 Mar 21;52(5):2273-2289. doi: 10.1093/nar/gkad1193. PMID: 38118002Free PMC Article
Tagliaferri L, Lancellotta V, Fionda B, Mangoni M, Casà C, Di Stefani A, Pagliara MM, D'Aviero A, Schinzari G, Chiesa S, Mazzarella C, Manfrida S, Colloca GF, Marazzi F, Morganti AG, Blasi MA, Peris K, Tortora G, Valentini V
Hum Vaccin Immunother 2022 May 31;18(3):1903827. Epub 2021 Apr 13 doi: 10.1080/21645515.2021.1903827. PMID: 33847208Free PMC Article
Carvajal R, Maniar R
Hematol Oncol Clin North Am 2021 Feb;35(1):85-98. Epub 2020 Oct 26 doi: 10.1016/j.hoc.2020.09.004. PMID: 33759775
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Laver NV, McLaughlin ME, Duker JS
Arch Pathol Lab Med 2010 Dec;134(12):1778-84. doi: 10.5858/2009-0441-RAR.1. PMID: 21128775

Diagnosis

Carvajal R, Maniar R
Hematol Oncol Clin North Am 2021 Feb;35(1):85-98. Epub 2020 Oct 26 doi: 10.1016/j.hoc.2020.09.004. PMID: 33759775
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Laver NV, McLaughlin ME, Duker JS
Arch Pathol Lab Med 2010 Dec;134(12):1778-84. doi: 10.5858/2009-0441-RAR.1. PMID: 21128775
Char DH
Surg Clin North Am 2003 Apr;83(2):253-74, vii. doi: 10.1016/S0039-6109(02)00098-1. PMID: 12744609
Grin-Jorgensen C, Berke A, Grin M
Dermatol Clin 1992 Oct;10(4):663-8. PMID: 1395150

Therapy

Dogrusöz M, Jager MJ
Acta Ophthalmol 2018 Jun;96(4):331-347. Epub 2017 Nov 4 doi: 10.1111/aos.13580. PMID: 29105334
Schachter J, Ribas A, Long GV, Arance A, Grob JJ, Mortier L, Daud A, Carlino MS, McNeil C, Lotem M, Larkin J, Lorigan P, Neyns B, Blank C, Petrella TM, Hamid O, Zhou H, Ebbinghaus S, Ibrahim N, Robert C
Lancet 2017 Oct 21;390(10105):1853-1862. Epub 2017 Aug 16 doi: 10.1016/S0140-6736(17)31601-X. PMID: 28822576
Mangana J, Levesque MP, Karpova MB, Dummer R
Expert Opin Investig Drugs 2012 Apr;21(4):557-68. Epub 2012 Mar 7 doi: 10.1517/13543784.2012.665872. PMID: 22394203
Spagnolo F, Caltabiano G, Queirolo P
Cancer Treat Rev 2012 Aug;38(5):549-53. Epub 2012 Jan 24 doi: 10.1016/j.ctrv.2012.01.002. PMID: 22270078
Moshfeghi DM, Moshfeghi AA, Finger PT
Surv Ophthalmol 2000 Jan-Feb;44(4):277-301. doi: 10.1016/s0039-6257(99)00112-5. PMID: 10667436

Prognosis

Masoomian B, Dalvin LA, Riazi-Esfahani H, Ghassemi F, Azizkhani M, Mirghorbani M, Khorrami-Nejad M, Sajjadi Z, Kaliki S, Sagoo MS, Al Harby L, Al-Jamal RT, Kivelä TT, Giblin M, Lim LS, Shields CL
J AAPOS 2023 Dec;27(6):316-324. Epub 2023 Nov 8 doi: 10.1016/j.jaapos.2023.08.021. PMID: 37949393
Yu J, Chai P, Xie M, Ge S, Ruan J, Fan X, Jia R
Genome Biol 2021 Mar 16;22(1):85. doi: 10.1186/s13059-021-02308-z. PMID: 33726814Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Laver NV, McLaughlin ME, Duker JS
Arch Pathol Lab Med 2010 Dec;134(12):1778-84. doi: 10.5858/2009-0441-RAR.1. PMID: 21128775
Grin-Jorgensen C, Berke A, Grin M
Dermatol Clin 1992 Oct;10(4):663-8. PMID: 1395150

Clinical prediction guides

Wu M, Yavuzyigitoglu S, Brosens E, Ramdas WD, Kiliç E; Rotterdam Ocular Melanoma Study Group (ROMS)
Invest Ophthalmol Vis Sci 2023 Oct 3;64(13):45. doi: 10.1167/iovs.64.13.45. PMID: 37902747Free PMC Article
Fionda B, Pagliara MM, Chyrek AJ, Guix B, O'Day RFJ, Fog LS, Martínez-Monge R, Tagliaferri L
Clin Oncol (R Coll Radiol) 2023 Aug;35(8):e445-e452. Epub 2023 Feb 6 doi: 10.1016/j.clon.2023.01.021. PMID: 36792447
Nowak MS, Romanowska-Dixon B, Grabska-Liberek I, Żurek M
Adv Clin Exp Med 2022 Jun;31(6):615-621. doi: 10.17219/acem/146581. PMID: 35349230
Tan LLY, Hong J, Goh WL, Chang EWY, Yang VS, Poon E, Somasundaram N, Farid M, Chan ASY, Chan JY
Sci Rep 2020 Oct 1;10(1):16367. doi: 10.1038/s41598-020-73534-x. PMID: 33004998Free PMC Article
Rajeev R, Gamblin TC, Turaga KK
Surg Clin North Am 2016 Apr;96(2):357-68. doi: 10.1016/j.suc.2015.12.005. PMID: 27017869

Recent systematic reviews

de Esteban Maciñeira E, Fernández Fernández P, Conde González I, Bande Rodríguez MF, Blanco Teijeiro MJ
Int Ophthalmol 2024 Jun 22;44(1):256. doi: 10.1007/s10792-024-03164-z. PMID: 38909111
Comito F, Marchese PV, Ricci AD, Tober N, Peterle C, Sperandi F, Melotti B
Future Oncol 2021 Nov;17(33):4583-4606. Epub 2021 Aug 25 doi: 10.2217/fon-2021-0318. PMID: 34431316
Messineo D, Barile G, Morrone S, La Torre G, Turchetti P, Accetta L, Trovato Battagliola E, Agostinelli E, Pacella F
Clin Ter 2020 Jan-Feb;170(1):e89-e98. doi: 10.7417/CT.2020.2195. PMID: 31916427
Steeb T, Wessely A, Ruzicka T, Heppt MV, Berking C
Eur J Cancer 2018 Nov;103:41-51. Epub 2018 Sep 8 doi: 10.1016/j.ejca.2018.08.005. PMID: 30205280
Mangana J, Levesque MP, Karpova MB, Dummer R
Expert Opin Investig Drugs 2012 Apr;21(4):557-68. Epub 2012 Mar 7 doi: 10.1517/13543784.2012.665872. PMID: 22394203

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