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Rosacea

MedGen UID:
11269
Concept ID:
C0035854
Disease or Syndrome
Synonym: Acne Rosacea
SNOMED CT: Rosacea (398909004); Acne rosacea (398909004); Acne erythematosa (398909004)
 
Monarch Initiative: MONDO:0006604

Definition

A chronic erythematous skin disorder that affects the face. It is characterized by the development of redness in the cheeks, nose, and/or forehead and telangiectasia. Sometimes, the erythematous changes may involve the eyelids. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRosacea

Professional guidelines

PubMed

Sharma A, Kroumpouzos G, Kassir M, Galadari H, Goren A, Grabbe S, Goldust M
J Cosmet Dermatol 2022 May;21(5):1895-1904. Epub 2022 Feb 14 doi: 10.1111/jocd.14816. PMID: 35104917
Kang CN, Shah M, Tan J
Skin Therapy Lett 2021 Jul;26(4):1-8. PMID: 34347259
van Zuuren EJ, Arents BWM, van der Linden MMD, Vermeulen S, Fedorowicz Z, Tan J
Am J Clin Dermatol 2021 Jul;22(4):457-465. Epub 2021 Mar 23 doi: 10.1007/s40257-021-00595-7. PMID: 33759078Free PMC Article

Recent clinical studies

Etiology

Guertler A, Volsky A, Eijkenboom Q, Fiedler T, French LE, Reinholz M
Nutrients 2023 Oct 17;15(20) doi: 10.3390/nu15204405. PMID: 37892480Free PMC Article
Calvisi L, Diaspro A, Sito G
J Cosmet Dermatol 2022 Sep;21(9):3747-3753. Epub 2022 Mar 21 doi: 10.1111/jocd.14692. PMID: 35312149
Aktaş Karabay E, Aksu Çerman A
An Bras Dermatol 2020 Mar-Apr;95(2):187-193. Epub 2020 Feb 12 doi: 10.1016/j.abd.2019.08.023. PMID: 32113677Free PMC Article
Schaller M, Almeida LMC, Bewley A, Cribier B, Del Rosso J, Dlova NC, Gallo RL, Granstein RD, Kautz G, Mannis MJ, Micali G, Oon HH, Rajagopalan M, Steinhoff M, Tanghetti E, Thiboutot D, Troielli P, Webster G, Zierhut M, van Zuuren EJ, Tan J
Br J Dermatol 2020 May;182(5):1269-1276. Epub 2019 Oct 16 doi: 10.1111/bjd.18420. PMID: 31392722Free PMC Article
Alexis AF, Callender VD, Baldwin HE, Desai SR, Rendon MI, Taylor SC
J Am Acad Dermatol 2019 Jun;80(6):1722-1729.e7. Epub 2018 Sep 19 doi: 10.1016/j.jaad.2018.08.049. PMID: 30240779

Diagnosis

Clanner-Engelshofen BM, Bernhard D, Dargatz S, Flaig MJ, Gieler U, Kinberger M, Klövekorn W, Kuna AC, Läuchli S, Lehmann P, Nast A, Pleyer U, Schaller M, Schöfer H, Steinhoff M, Schwennesen T, Werner RN, Zierhut M, Reinholz M
J Dtsch Dermatol Ges 2022 Aug;20(8):1147-1165. Epub 2022 Aug 5 doi: 10.1111/ddg.14849. PMID: 35929658
Kang CN, Shah M, Tan J
Skin Therapy Lett 2021 Jul;26(4):1-8. PMID: 34347259
van Zuuren EJ, Arents BWM, van der Linden MMD, Vermeulen S, Fedorowicz Z, Tan J
Am J Clin Dermatol 2021 Jul;22(4):457-465. Epub 2021 Mar 23 doi: 10.1007/s40257-021-00595-7. PMID: 33759078Free PMC Article
Searle T, Al-Niaimi F, Ali FR
Br J Hosp Med (Lond) 2021 Feb 2;82(2):1-8. Epub 2021 Feb 27 doi: 10.12968/hmed.2020.0417. PMID: 33646026
Buddenkotte J, Steinhoff M
F1000Res 2018;7 Epub 2018 Dec 3 doi: 10.12688/f1000research.16537.1. PMID: 30631431Free PMC Article

Therapy

Ivanic MG, Oulee A, Norden A, Javadi SS, Gold MH, Wu JJ
J Drugs Dermatol 2023 Jun 1;22(6):566-575. doi: 10.36849/JDD.7181. PMID: 37276164
Gomolin T, Cline A, Pereira F
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754360. PMID: 34391325
Kang CN, Shah M, Tan J
Skin Therapy Lett 2021 Jul;26(4):1-8. PMID: 34347259
Searle T, Al-Niaimi F, Ali FR
Br J Hosp Med (Lond) 2021 Feb 2;82(2):1-8. Epub 2021 Feb 27 doi: 10.12968/hmed.2020.0417. PMID: 33646026
Oge' LK, Muncie HL, Phillips-Savoy AR
Am Fam Physician 2015 Aug 1;92(3):187-96. PMID: 26280139

Prognosis

Kępińska K, Jałowska M, Bowszyc-Dmochowska M
Ann Agric Environ Med 2022 Jun 24;29(2):169-184. Epub 2021 Aug 31 doi: 10.26444/aaem/141324. PMID: 35767748
Alia E, Feng H
Clin Dermatol 2022 Mar-Apr;40(2):122-127. Epub 2021 Oct 27 doi: 10.1016/j.clindermatol.2021.10.004. PMID: 34819228
Zhang H, Zhang Y, Li Y, Wang Y, Yan S, Xu S, Deng Z, Yang X, Xie H, Li J
Front Immunol 2021;12:756550. Epub 2021 Nov 23 doi: 10.3389/fimmu.2021.756550. PMID: 34899707Free PMC Article
Jacob S, VanDaele MA, Brown JN
Dermatol Ther 2019 Nov;32(6):e13103. Epub 2019 Oct 28 doi: 10.1111/dth.13103. PMID: 31583801
Gallo RL, Granstein RD, Kang S, Mannis M, Steinhoff M, Tan J, Thiboutot D
J Am Acad Dermatol 2018 Jan;78(1):148-155. Epub 2017 Oct 28 doi: 10.1016/j.jaad.2017.08.037. PMID: 29089180

Clinical prediction guides

Guertler A, Volsky A, Eijkenboom Q, Fiedler T, French LE, Reinholz M
Nutrients 2023 Oct 17;15(20) doi: 10.3390/nu15204405. PMID: 37892480Free PMC Article
Wang B, Huang Y, Tang Y, Zhao Z, Shi W, Jian D, Liu F, Gao Q, Wang P, Yang J, Li L, Xie H, Li J
J Am Acad Dermatol 2023 Jun;88(6):1300-1307. Epub 2023 Feb 15 doi: 10.1016/j.jaad.2023.01.044. PMID: 36806645
Zhang H, Zhang Y, Li Y, Wang Y, Yan S, Xu S, Deng Z, Yang X, Xie H, Li J
Front Immunol 2021;12:756550. Epub 2021 Nov 23 doi: 10.3389/fimmu.2021.756550. PMID: 34899707Free PMC Article
Li Y, Yang L, Wang Y, Deng Z, Xu S, Xie H, Zhang Y, Li J
Pharmacol Res 2021 Dec;174:105971. Epub 2021 Nov 8 doi: 10.1016/j.phrs.2021.105971. PMID: 34763093
Hernández Ceruelos A, Romero-Quezada LC, Ruvalcaba Ledezma JC, López Contreras L
Eur Rev Med Pharmacol Sci 2019 Jan;23(1):397-401. doi: 10.26355/eurrev_201901_16788. PMID: 30657582

Recent systematic reviews

Reynolds RV, Yeung H, Cheng CE, Cook-Bolden F, Desai SR, Druby KM, Freeman EE, Keri JE, Stein Gold LF, Tan JKL, Tollefson MM, Weiss JS, Wu PA, Zaenglein AL, Han JM, Barbieri JS
J Am Acad Dermatol 2024 May;90(5):1006.e1-1006.e30. Epub 2024 Jan 30 doi: 10.1016/j.jaad.2023.12.017. PMID: 38300170
King S, Campbell J, Rowe R, Daly ML, Moncrieff G, Maybury C
J Cosmet Dermatol 2023 Oct;22(10):2650-2662. Epub 2023 Aug 7 doi: 10.1111/jocd.15923. PMID: 37550898
Hwang J, Lio PA
J Dermatolog Treat 2022 May;33(3):1293-1298. Epub 2021 Feb 4 doi: 10.1080/09546634.2021.1882659. PMID: 33499686
Yee BE, Richards P, Sui JY, Marsch AF
Dermatol Ther 2020 Nov;33(6):e14252. Epub 2020 Sep 15 doi: 10.1111/dth.14252. PMID: 32860489
van Zuuren EJ, Fedorowicz Z, Carter B, van der Linden MM, Charland L
Cochrane Database Syst Rev 2015 Apr 28;2015(4):CD003262. doi: 10.1002/14651858.CD003262.pub5. PMID: 25919144Free PMC Article

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