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Childhood Rhabdomyosarcoma

MedGen UID:
113091
Concept ID:
C0220611
Neoplastic Process
Synonym: Pediatric Rhabdomyosarcoma

Definition

An aggressive malignant mesenchymal neoplasm arising from skeletal muscle in children. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomic sites. [from NCI]

Professional guidelines

PubMed

Brown BJ, Ogun GO, Akinmoladun VI, Ogundoyin OO, Abdus-Salam A, Olulana DI, Lawal TA
J Pediatr Hematol Oncol 2021 Jul 1;43(5):e625-e629. doi: 10.1097/MPH.0000000000002093. PMID: 33625089
Mandeville HC
Clin Oncol (R Coll Radiol) 2019 Jul;31(7):462-470. Epub 2019 Apr 13 doi: 10.1016/j.clon.2019.03.047. PMID: 30992168
Huh WW, Skapek SX
Curr Oncol Rep 2010 Nov;12(6):402-10. doi: 10.1007/s11912-010-0130-3. PMID: 20820958

Recent clinical studies

Etiology

Brown BJ, Ogun GO, Akinmoladun VI, Ogundoyin OO, Abdus-Salam A, Olulana DI, Lawal TA
J Pediatr Hematol Oncol 2021 Jul 1;43(5):e625-e629. doi: 10.1097/MPH.0000000000002093. PMID: 33625089
Mandeville HC
Clin Oncol (R Coll Radiol) 2019 Jul;31(7):462-470. Epub 2019 Apr 13 doi: 10.1016/j.clon.2019.03.047. PMID: 30992168
Wang C
J Dent Res 2012 Apr;91(4):341-50. Epub 2011 Sep 13 doi: 10.1177/0022034511421490. PMID: 21917598Free PMC Article
Huh WW, Skapek SX
Curr Oncol Rep 2010 Nov;12(6):402-10. doi: 10.1007/s11912-010-0130-3. PMID: 20820958
Rodeberg D, Paidas C
Semin Pediatr Surg 2006 Feb;15(1):57-62. doi: 10.1053/j.sempedsurg.2005.11.009. PMID: 16458847

Diagnosis

Brown BJ, Ogun GO, Akinmoladun VI, Ogundoyin OO, Abdus-Salam A, Olulana DI, Lawal TA
J Pediatr Hematol Oncol 2021 Jul 1;43(5):e625-e629. doi: 10.1097/MPH.0000000000002093. PMID: 33625089
Córdoba Rovira SM, Inarejos Clemente EJ
Radiologia 2016 Nov-Dec;58(6):481-490. Epub 2016 Nov 1 doi: 10.1016/j.rx.2016.09.003. PMID: 27810092
Huh WW, Skapek SX
Curr Oncol Rep 2010 Nov;12(6):402-10. doi: 10.1007/s11912-010-0130-3. PMID: 20820958
Rodeberg D, Paidas C
Semin Pediatr Surg 2006 Feb;15(1):57-62. doi: 10.1053/j.sempedsurg.2005.11.009. PMID: 16458847
McDowell HP
Arch Dis Child 2003 Apr;88(4):354-7. doi: 10.1136/adc.88.4.354. PMID: 12651771Free PMC Article

Therapy

Lupo PJ, Danysh HE, Skapek SX, Hawkins DS, Spector LG, Zhou R, Okcu MF, Papworth K, Erhardt EB, Grufferman S
Cancer Causes Control 2014 Jul;25(7):905-13. Epub 2014 May 16 doi: 10.1007/s10552-014-0390-6. PMID: 24831857Free PMC Article
Kojima Y, Hashimoto K, Ando M, Yonemori K, Hirakawa A, Kodaira M, Yunokawa M, Shimizu C, Tamura K, Katsumata N, Hosono A, Makimoto A, Fujiwara Y
J Cancer Res Clin Oncol 2012 Jul;138(7):1249-57. Epub 2012 Mar 23 doi: 10.1007/s00432-012-1199-x. PMID: 22441933
Huh WW, Skapek SX
Curr Oncol Rep 2010 Nov;12(6):402-10. doi: 10.1007/s11912-010-0130-3. PMID: 20820958
Stevens MC
Lancet Oncol 2005 Feb;6(2):77-84. doi: 10.1016/S1470-2045(05)01733-X. PMID: 15683816
McDowell HP
Arch Dis Child 2003 Apr;88(4):354-7. doi: 10.1136/adc.88.4.354. PMID: 12651771Free PMC Article

Prognosis

Guo J, Johansson I, Mkrtchian S, Ingelman-Sundberg M
Drug Metab Rev 2016 Aug;48(3):369-78. Epub 2016 Jun 3 doi: 10.1080/03602532.2016.1188939. PMID: 27257736
Wang C
J Dent Res 2012 Apr;91(4):341-50. Epub 2011 Sep 13 doi: 10.1177/0022034511421490. PMID: 21917598Free PMC Article
Huh WW, Skapek SX
Curr Oncol Rep 2010 Nov;12(6):402-10. doi: 10.1007/s11912-010-0130-3. PMID: 20820958
Rodeberg D, Paidas C
Semin Pediatr Surg 2006 Feb;15(1):57-62. doi: 10.1053/j.sempedsurg.2005.11.009. PMID: 16458847
McDowell HP
Arch Dis Child 2003 Apr;88(4):354-7. doi: 10.1136/adc.88.4.354. PMID: 12651771Free PMC Article

Clinical prediction guides

Ahuja M, Tomar R, Thakur S, Mallya V, Mandal S, Khurana N, Sarin YK
Indian J Pathol Microbiol 2022 Oct-Dec;65(4):864-868. doi: 10.4103/ijpm.ijpm_178_21. PMID: 36308195
Zhu L, Sun Y, Wang X, Wang L, Zhang S, Meng Q, Wang X
Sci Rep 2020 Mar 30;10(1):5684. doi: 10.1038/s41598-020-62656-x. PMID: 32231229Free PMC Article
Guo J, Johansson I, Mkrtchian S, Ingelman-Sundberg M
Drug Metab Rev 2016 Aug;48(3):369-78. Epub 2016 Jun 3 doi: 10.1080/03602532.2016.1188939. PMID: 27257736
Norman G, Fayter D, Lewis-Light K, Chisholm J, McHugh K, Levine D, Jenney M, Mandeville H, Gatz S, Phillips B
BMJ Open 2015 Jan 8;5(1):e006030. doi: 10.1136/bmjopen-2014-006030. PMID: 25573522Free PMC Article
Huh WW, Skapek SX
Curr Oncol Rep 2010 Nov;12(6):402-10. doi: 10.1007/s11912-010-0130-3. PMID: 20820958

Recent systematic reviews

Papyan R, Tamamyan G, Danielyan S, Tananyan A, Muradyan A, Saab R
Pediatr Blood Cancer 2019 Jul;66(7):e27708. Epub 2019 Mar 25 doi: 10.1002/pbc.27708. PMID: 30907501
Norman G, Fayter D, Lewis-Light K, Chisholm J, McHugh K, Levine D, Jenney M, Mandeville H, Gatz S, Phillips B
BMJ Open 2015 Jan 8;5(1):e006030. doi: 10.1136/bmjopen-2014-006030. PMID: 25573522Free PMC Article

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