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Carotid sinus syncope

MedGen UID:
113141
Concept ID:
C0221046
Disease or Syndrome
Synonyms: Carotid Sinus Syncope; Carotid Sinus Syncopes; Syncope, Carotid Sinus; Syncopes, Carotid Sinus
SNOMED CT: Carotid sinus syncope (51723007); Carotid sinus syndrome (51723007)
 
HPO: HP:0012669

Definition

An exaggerated response to carotid sinus baroreceptor stimulation resulting in syncope from transient diminished cerebral perfusion. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCarotid sinus syncope

Professional guidelines

PubMed

Ntusi NA, Coccia CB, Cupido BJ, Chin A
S Afr Med J 2015 Aug;105(8):690-3. doi: 10.7196/samjnew.8065. PMID: 26543940
Hussain RM, McIntosh SJ, Lawson J, Kenny RA
Heart 1996 Dec;76(6):507-9. doi: 10.1136/hrt.76.6.507. PMID: 9014799Free PMC Article
Maloney JD, Jaeger FJ, Rizo-Patron C, Zhu DW
Am Heart J 1994 Apr;127(4 Pt 2):1030-7. doi: 10.1016/0002-8703(94)90083-3. PMID: 8160577

Recent clinical studies

Etiology

Romano S, Branz L, Fondrieschi L, Minuz P
High Blood Press Cardiovasc Prev 2019 Aug;26(4):273-281. Epub 2019 Jul 11 doi: 10.1007/s40292-019-00327-3. PMID: 31297720
Ungar A, Rivasi G, Rafanelli M, Toffanello G, Mussi C, Ceccofiglio A, McDonagh R, Drumm B, Marchionni N, Alboni P, Kenny RA
Age Ageing 2016 Mar;45(2):242-8. Epub 2016 Jan 31 doi: 10.1093/ageing/afw004. PMID: 26833302
Alboni P
Heart 2015 May;101(9):674-8. Epub 2015 Mar 19 doi: 10.1136/heartjnl-2014-307096. PMID: 25792719
Romme JJ, Reitsma JB, Black CN, Colman N, Scholten RJ, Wieling W, Van Dijk N
Cochrane Database Syst Rev 2011 Oct 5;(10):CD004194. doi: 10.1002/14651858.CD004194.pub3. PMID: 21975744
Trout HH 3rd, Brown LL, Thompson JE
Ann Surg 1979 May;189(5):575-80. doi: 10.1097/00000658-197905000-00006. PMID: 443910Free PMC Article

Diagnosis

Romano S, Branz L, Fondrieschi L, Minuz P
High Blood Press Cardiovasc Prev 2019 Aug;26(4):273-281. Epub 2019 Jul 11 doi: 10.1007/s40292-019-00327-3. PMID: 31297720
Ungar A, Rivasi G, Rafanelli M, Toffanello G, Mussi C, Ceccofiglio A, McDonagh R, Drumm B, Marchionni N, Alboni P, Kenny RA
Age Ageing 2016 Mar;45(2):242-8. Epub 2016 Jan 31 doi: 10.1093/ageing/afw004. PMID: 26833302
Alboni P
Heart 2015 May;101(9):674-8. Epub 2015 Mar 19 doi: 10.1136/heartjnl-2014-307096. PMID: 25792719
Bauer CA, Redleaf MI, Gartlan MG, Tsue TT, McColloch TM
Laryngoscope 1994 Apr;104(4):497-503. doi: 10.1288/00005537-199404000-00018. PMID: 8164493
Morley CA, Sutton R
Int J Cardiol 1984 Sep;6(3):287-93. doi: 10.1016/0167-5273(84)90188-8. PMID: 6480160

Therapy

Ungar A, Rivasi G, Rafanelli M, Toffanello G, Mussi C, Ceccofiglio A, McDonagh R, Drumm B, Marchionni N, Alboni P, Kenny RA
Age Ageing 2016 Mar;45(2):242-8. Epub 2016 Jan 31 doi: 10.1093/ageing/afw004. PMID: 26833302
Romme JJ, Reitsma JB, Black CN, Colman N, Scholten RJ, Wieling W, Van Dijk N
Cochrane Database Syst Rev 2011 Oct 5;(10):CD004194. doi: 10.1002/14651858.CD004194.pub3. PMID: 21975744
Martinez-Fernandez E, Boza Garcia F, Gonzalez-Marcos JR, Gil-Peralta A, Gonzalez Garcia A, Mayol Deya A
Stroke 2008 Apr;39(4):1336-9. Epub 2008 Feb 28 doi: 10.1161/STROKEAHA.107.501627. PMID: 18309152
Hussain RM, McIntosh SJ, Lawson J, Kenny RA
Heart 1996 Dec;76(6):507-9. doi: 10.1136/hrt.76.6.507. PMID: 9014799Free PMC Article
Rentmeester T, Van Zile J, Van Hal M, Levene D
Br Med J (Clin Res Ed) 1984 Sep 22;289(6447):720. doi: 10.1136/bmj.289.6447.720. PMID: 6434054Free PMC Article

Prognosis

Ungar A, Rivasi G, Rafanelli M, Toffanello G, Mussi C, Ceccofiglio A, McDonagh R, Drumm B, Marchionni N, Alboni P, Kenny RA
Age Ageing 2016 Mar;45(2):242-8. Epub 2016 Jan 31 doi: 10.1093/ageing/afw004. PMID: 26833302
Ntusi NA, Coccia CB, Cupido BJ, Chin A
S Afr Med J 2015 Aug;105(8):690-3. doi: 10.7196/samjnew.8065. PMID: 26543940
Martinez-Fernandez E, García FB, Gonzalez-Marcos JR, Peralta AG, Garcia AG, Deya AM
AJNR Am J Neuroradiol 2008 Feb;29(2):269-72. Epub 2007 Nov 1 doi: 10.3174/ajnr.A0823. PMID: 17974603Free PMC Article
Hammill SC
Cardiol Clin 1997 May;15(2):195-218. doi: 10.1016/s0733-8651(05)70330-1. PMID: 9164710
Trout HH 3rd, Brown LL, Thompson JE
Ann Surg 1979 May;189(5):575-80. doi: 10.1097/00000658-197905000-00006. PMID: 443910Free PMC Article

Clinical prediction guides

Ungar A, Rivasi G, Rafanelli M, Toffanello G, Mussi C, Ceccofiglio A, McDonagh R, Drumm B, Marchionni N, Alboni P, Kenny RA
Age Ageing 2016 Mar;45(2):242-8. Epub 2016 Jan 31 doi: 10.1093/ageing/afw004. PMID: 26833302
Brignole M, Sutton R, Menozzi C, Garcia-Civera R, Moya A, Wieling W, Andresen D, Benditt DG, Grovale N, De Santo T, Vardas P; International Study on Syncope of Uncertain Etiology 2 (ISSUE 2) Group
Eur Heart J 2006 Sep;27(18):2232-9. Epub 2006 Jul 24 doi: 10.1093/eurheartj/ehl164. PMID: 16864606
Brignole M, Sutton R, Menozzi C, Garcia-Civera R, Moya A, Wieling W, Andresen D, Benditt DG, Vardas P; International Study on Syncope of Uncertain Etiology 2 (ISSUE 2) Group
Eur Heart J 2006 May;27(9):1085-92. Epub 2006 Mar 28 doi: 10.1093/eurheartj/ehi842. PMID: 16569653
Hammill SC
Cardiol Clin 1997 May;15(2):195-218. doi: 10.1016/s0733-8651(05)70330-1. PMID: 9164710
Solti F, Szabó Z, Czakó E, Bodor E, Rényi-Vámos F Jr
Z Kardiol 1980 Sep;69(9):656-9. PMID: 7210771

Recent systematic reviews

Romme JJ, Reitsma JB, Black CN, Colman N, Scholten RJ, Wieling W, Van Dijk N
Cochrane Database Syst Rev 2011 Oct 5;(10):CD004194. doi: 10.1002/14651858.CD004194.pub3. PMID: 21975744

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