U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Coxsackievirus infectious disease

MedGen UID:
1159
Concept ID:
C0010246
Disease or Syndrome
Synonyms: Coxsackie Virus Infection; Coxsackie Virus Infections; Coxsackievirus Infection; Coxsackievirus Infections; Infections, Coxsackie Virus; Infections, Coxsackievirus
SNOMED CT: Coxsackie virus disease (186658007)
 
Monarch Initiative: MONDO:0005721

Definition

A heterogeneous group of infections produced by coxsackieviruses, including herpangina, aseptic meningitis (meningitis, aseptic), a common-cold-like syndrome, a non-paralytic poliomyelitis-like syndrome, epidemic pleurodynia (pleurodynia, epidemic) and a serious myocarditis. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCoxsackievirus infectious disease

Professional guidelines

PubMed

Auriti C, De Rose DU, Santisi A, Martini L, Piersigilli F, Bersani I, Ronchetti MP, Caforio L
Biochim Biophys Acta Mol Basis Dis 2021 Oct 1;1867(10):166198. Epub 2021 Jun 10 doi: 10.1016/j.bbadis.2021.166198. PMID: 34118406Free PMC Article
Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA; AFM working group
Lancet 2021 Jan 23;397(10271):334-346. Epub 2020 Dec 23 doi: 10.1016/S0140-6736(20)32723-9. PMID: 33357469Free PMC Article
Yu H, Li XW, Liu QB, Deng HL, Liu G, Jiang RM, Deng JK, Ye YZ, Hao JH, Chen YH, Nong GM, Shen ZB, Liu CS, Zou YX, Wu JZ, Wu XD, Chen BQ, Luo RP, Lin AW, Chen Y, Liu XD
World J Pediatr 2020 Apr;16(2):129-134. Epub 2019 Jul 25 doi: 10.1007/s12519-019-00277-9. PMID: 31347021

Recent clinical studies

Etiology

Penner J, Hernstadt H, Burns JE, Randell P, Lyall H
Arch Dis Child 2021 Feb;106(2):117-124. Epub 2020 Jun 25 doi: 10.1136/archdischild-2020-318841. PMID: 32586930
Dong Y, Wang L, Burgner DP, Miller JE, Song Y, Ren X, Li Z, Xing Y, Ma J, Sawyer SM, Patton GC
BMJ 2020 Apr 2;369:m1043. doi: 10.1136/bmj.m1043. PMID: 32241761Free PMC Article
Chuang YY, Huang YC
J Microbiol Immunol Infect 2019 Dec;52(6):851-857. Epub 2019 Sep 30 doi: 10.1016/j.jmii.2019.08.018. PMID: 31607572
Grill MF
Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):441-473. doi: 10.1212/CON.0000000000000597. PMID: 29613895
Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ
Infect Dis Clin North Am 2018 Mar;32(1):145-162. Epub 2017 Dec 8 doi: 10.1016/j.idc.2017.10.007. PMID: 29224854Free PMC Article

Diagnosis

Penner J, Hernstadt H, Burns JE, Randell P, Lyall H
Arch Dis Child 2021 Feb;106(2):117-124. Epub 2020 Jun 25 doi: 10.1136/archdischild-2020-318841. PMID: 32586930
Chuang YY, Huang YC
J Microbiol Immunol Infect 2019 Dec;52(6):851-857. Epub 2019 Sep 30 doi: 10.1016/j.jmii.2019.08.018. PMID: 31607572
Grill MF
Continuum (Minneap Minn) 2018 Apr;24(2, Spinal Cord Disorders):441-473. doi: 10.1212/CON.0000000000000597. PMID: 29613895
Esposito S, Principi N
Eur J Clin Microbiol Infect Dis 2018 Mar;37(3):391-398. Epub 2018 Feb 6 doi: 10.1007/s10096-018-3206-x. PMID: 29411190
Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ
Infect Dis Clin North Am 2018 Mar;32(1):145-162. Epub 2017 Dec 8 doi: 10.1016/j.idc.2017.10.007. PMID: 29224854Free PMC Article

Therapy

Tschöpe C, Ammirati E, Bozkurt B, Caforio ALP, Cooper LT, Felix SB, Hare JM, Heidecker B, Heymans S, Hübner N, Kelle S, Klingel K, Maatz H, Parwani AS, Spillmann F, Starling RC, Tsutsui H, Seferovic P, Van Linthout S
Nat Rev Cardiol 2021 Mar;18(3):169-193. Epub 2020 Oct 12 doi: 10.1038/s41569-020-00435-x. PMID: 33046850Free PMC Article
Yeh MT, Bujaki E, Dolan PT, Smith M, Wahid R, Konz J, Weiner AJ, Bandyopadhyay AS, Van Damme P, De Coster I, Revets H, Macadam A, Andino R
Cell Host Microbe 2020 May 13;27(5):736-751.e8. Epub 2020 Apr 23 doi: 10.1016/j.chom.2020.04.003. PMID: 32330425Free PMC Article
Chuang YY, Huang YC
J Microbiol Immunol Infect 2019 Dec;52(6):851-857. Epub 2019 Sep 30 doi: 10.1016/j.jmii.2019.08.018. PMID: 31607572
Baggen J, Thibaut HJ, Strating JRPM, van Kuppeveld FJM
Nat Rev Microbiol 2018 Jun;16(6):368-381. doi: 10.1038/s41579-018-0005-4. PMID: 29626210
Minor P
Hum Vaccin Immunother 2014;10(7):2106-8. doi: 10.4161/21645515.2014.981115. PMID: 25608050Free PMC Article

Prognosis

Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA; AFM working group
Lancet 2021 Jan 23;397(10271):334-346. Epub 2020 Dec 23 doi: 10.1016/S0140-6736(20)32723-9. PMID: 33357469Free PMC Article
Tschöpe C, Ammirati E, Bozkurt B, Caforio ALP, Cooper LT, Felix SB, Hare JM, Heidecker B, Heymans S, Hübner N, Kelle S, Klingel K, Maatz H, Parwani AS, Spillmann F, Starling RC, Tsutsui H, Seferovic P, Van Linthout S
Nat Rev Cardiol 2021 Mar;18(3):169-193. Epub 2020 Oct 12 doi: 10.1038/s41569-020-00435-x. PMID: 33046850Free PMC Article
Gonzalez G, Carr MJ, Kobayashi M, Hanaoka N, Fujimoto T
Int J Mol Sci 2019 Oct 20;20(20) doi: 10.3390/ijms20205201. PMID: 31635198Free PMC Article
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Jubelt B, Mihai C, Li TM, Veerapaneni P
Curr Neurol Neurosci Rep 2011 Dec;11(6):543-52. doi: 10.1007/s11910-011-0228-5. PMID: 21956758

Clinical prediction guides

Vermillion MS, Dearing J, Zhang Y, Adney DR, Scheuermann RH, Pekosz A, Tarbet EB
J Virol 2022 Aug 10;96(15):e0083322. Epub 2022 Jul 19 doi: 10.1128/jvi.00833-22. PMID: 35852353Free PMC Article
Auriti C, De Rose DU, Santisi A, Martini L, Piersigilli F, Bersani I, Ronchetti MP, Caforio L
Biochim Biophys Acta Mol Basis Dis 2021 Oct 1;1867(10):166198. Epub 2021 Jun 10 doi: 10.1016/j.bbadis.2021.166198. PMID: 34118406Free PMC Article
Zhang M, Wang H, Tang J, He Y, Xiong T, Li W, Qu Y, Mu D
BMC Pediatr 2021 Mar 15;21(1):127. doi: 10.1186/s12887-021-02599-y. PMID: 33722228Free PMC Article
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Carod-Artal FJ
Clin Auton Res 2018 Feb;28(1):67-81. Epub 2017 Jul 20 doi: 10.1007/s10286-017-0452-4. PMID: 28730326

Recent systematic reviews

Shi Y, Chen P, Bai Y, Xu X, Liu Y
Arch Virol 2023 Jan 7;168(2):37. doi: 10.1007/s00705-022-05642-0. PMID: 36609748Free PMC Article
Zhang M, Wang H, Tang J, He Y, Xiong T, Li W, Qu Y, Mu D
BMC Pediatr 2021 Mar 15;21(1):127. doi: 10.1186/s12887-021-02599-y. PMID: 33722228Free PMC Article
Jones E, Pillay TD, Liu F, Luo L, Bazo-Alvarez JC, Yuan C, Zhao S, Chen Q, Li Y, Liao Q, Yu H, Rogier van Doorn H, Sabanathan S
Eur J Paediatr Neurol 2018 Sep;22(5):763-773. Epub 2018 Apr 20 doi: 10.1016/j.ejpn.2018.04.007. PMID: 29778429Free PMC Article
Akram M, Tahir IM, Shah SMA, Mahmood Z, Altaf A, Ahmad K, Munir N, Daniyal M, Nasir S, Mehboob H
Phytother Res 2018 May;32(5):811-822. Epub 2018 Jan 22 doi: 10.1002/ptr.6024. PMID: 29356205
Chan JH, Law CK, Hamblion E, Fung H, Rudge J
Hong Kong Med J 2017 Apr;23(2):177-90. Epub 2017 Mar 17 doi: 10.12809/hkmj166098. PMID: 28302925

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...