U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tenderness

MedGen UID:
115948
•Concept ID:
C0234233
•
Sign or Symptom
Synonyms: Sore pain; Sore to touch; Soreness
SNOMED CT: Soreness (71393004); Sore to touch (247348008); Tenderness (247348008); Sore pain (71393004)

Definition

A dull achy pain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTenderness

Professional guidelines

PubMed

Evaluation and Treatment of Knee Pain: A Review.
Duong V, Oo WM, Ding C, Culvenor AG, Hunter DJ
JAMA 2023 Oct 24;330(16):1568-1580. doi: 10.1001/jama.2023.19675. PMID: 37874571
Upper Gastrointestinal Bleeding in Adults: Evaluation and Management.
Wilkins T, Wheeler B, Carpenter M
Am Fam Physician 2020 Mar 1;101(5):294-300. PMID: 32109037
Pelvic Inflammatory Disease: Diagnosis, Management, and Prevention.
Curry A, Williams T, Penny ML
Am Fam Physician 2019 Sep 15;100(6):357-364. PMID: 31524362

Recent clinical studies

Etiology

Tenderness and radiographic progression in rheumatoid arthritis and psoriatic arthritis.
Gessl I, Hana CA, Deimel T, Durechova M, Hucke M, Konzett V, Popescu M, Studenic P, Supp G, Zauner M, Smolen JS, Aletaha D, Mandl P
Ann Rheum Dis 2023 Mar;82(3):344-350. Epub 2022 Oct 19 doi: 10.1136/ard-2022-222787. PMID: 36261248
A Randomized Controlled Trial of Ceftriaxone and Doxycycline, With or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease.
Wiesenfeld HC, Meyn LA, Darville T, Macio IS, Hillier SL
Clin Infect Dis 2021 Apr 8;72(7):1181-1189. doi: 10.1093/cid/ciaa101. PMID: 32052831Free PMC Article
Perineal Massage Improves the Dyspareunia Caused by Tenderness of the Pelvic Floor Muscles.
Silva AP, Montenegro ML, Gurian MB, Mitidieri AM, Lara LA, Poli-Neto OB, Rosa E Silva JC
Rev Bras Ginecol Obstet 2017 Jan;39(1):26-30. Epub 2016 Dec 27 doi: 10.1055/s-0036-1597651. PMID: 28027568
Scaphoid fractures.
Fowler JR, Hughes TB
Clin Sports Med 2015 Jan;34(1):37-50. Epub 2014 Nov 25 doi: 10.1016/j.csm.2014.09.011. PMID: 25455395
The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee.
Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P
Arthritis Rheum 1990 Feb;33(2):160-72. doi: 10.1002/art.1780330203. PMID: 2306288

Diagnosis

Mesenteric Ischemia: A Deadly Miss.
Singh M, Long B, Koyfman A
Emerg Med Clin North Am 2017 Nov;35(4):879-888. doi: 10.1016/j.emc.2017.07.005. PMID: 28987434
Perineal Massage Improves the Dyspareunia Caused by Tenderness of the Pelvic Floor Muscles.
Silva AP, Montenegro ML, Gurian MB, Mitidieri AM, Lara LA, Poli-Neto OB, Rosa E Silva JC
Rev Bras Ginecol Obstet 2017 Jan;39(1):26-30. Epub 2016 Dec 27 doi: 10.1055/s-0036-1597651. PMID: 28027568
Scaphoid fractures.
Fowler JR, Hughes TB
Clin Sports Med 2015 Jan;34(1):37-50. Epub 2014 Nov 25 doi: 10.1016/j.csm.2014.09.011. PMID: 25455395
Latent myofascial trigger points.
Ge HY, Arendt-Nielsen L
Curr Pain Headache Rep 2011 Oct;15(5):386-92. doi: 10.1007/s11916-011-0210-6. PMID: 21559783
Spigelian hernia.
Spangen L
World J Surg 1989 Sep-Oct;13(5):573-80. doi: 10.1007/BF01658873. PMID: 2683401

Therapy

Chest physiotherapy for pneumonia in adults.
Chen X, Jiang J, Wang R, Fu H, Lu J, Yang M
Cochrane Database Syst Rev 2022 Sep 6;9(9):CD006338. doi: 10.1002/14651858.CD006338.pub4. PMID: 36066373Free PMC Article
Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial.
Huttner A, Kowalczyk A, Turjeman A, Babich T, Brossier C, Eliakim-Raz N, Kosiek K, Martinez de Tejada B, Roux X, Shiber S, Theuretzbacher U, von Dach E, Yahav D, Leibovici L, Godycki-Cwirko M, Mouton JW, Harbarth S
JAMA 2018 May 1;319(17):1781-1789. doi: 10.1001/jama.2018.3627. PMID: 29710295Free PMC Article
Aquatic exercise for the treatment of knee and hip osteoarthritis.
Bartels EM, Juhl CB, Christensen R, Hagen KB, Danneskiold-Samsøe B, Dagfinrud H, Lund H
Cochrane Database Syst Rev 2016 Mar 23;3(3):CD005523. doi: 10.1002/14651858.CD005523.pub3. PMID: 27007113Free PMC Article
Resistance exercise training for fibromyalgia.
Busch AJ, Webber SC, Richards RS, Bidonde J, Schachter CL, Schafer LA, Danyliw A, Sawant A, Dal Bello-Haas V, Rader T, Overend TJ
Cochrane Database Syst Rev 2013 Dec 20;2013(12):CD010884. doi: 10.1002/14651858.CD010884. PMID: 24362925Free PMC Article
The effectiveness of hydrotherapy in the management of rheumatoid arthritis: a systematic review.
Al-Qubaeissy KY, Fatoye FA, Goodwin PC, Yohannes AM
Musculoskeletal Care 2013 Mar;11(1):3-18. Epub 2012 Jul 16 doi: 10.1002/msc.1028. PMID: 22806987

Prognosis

Medial tibial stress fracture diagnosis and treatment guidelines.
Milgrom C, Zloczower E, Fleischmann C, Spitzer E, Landau R, Bader T, Finestone AS
J Sci Med Sport 2021 Jun;24(6):526-530. Epub 2020 Dec 3 doi: 10.1016/j.jsams.2020.11.015. PMID: 33298373
Plantar fasciopathy.
Rompe JD
Sports Med Arthrosc Rev 2009 Jun;17(2):100-4. doi: 10.1097/JSA.0b013e3181a3d60e. PMID: 19440137
Plantar fasciitis: evaluation and treatment.
Neufeld SK, Cerrato R
J Am Acad Orthop Surg 2008 Jun;16(6):338-46. doi: 10.5435/00124635-200806000-00006. PMID: 18524985
Laryngeal trauma in sport.
Paluska SA, Lansford CD
Curr Sports Med Rep 2008 Feb;7(1):16-21. doi: 10.1097/01.CSMR.0000308673.53182.72. PMID: 18296939
A randomized controlled trial of exercise and manipulative therapy for cervicogenic headache.
Jull G, Trott P, Potter H, Zito G, Niere K, Shirley D, Emberson J, Marschner I, Richardson C
Spine (Phila Pa 1976) 2002 Sep 1;27(17):1835-43; discussion 1843. doi: 10.1097/00007632-200209010-00004. PMID: 12221344

Clinical prediction guides

Cellulitis: A Review of Pathogenesis, Diagnosis, and Management.
Rrapi R, Chand S, Kroshinsky D
Med Clin North Am 2021 Jul;105(4):723-735. doi: 10.1016/j.mcna.2021.04.009. PMID: 34059247
Evaluating an Algorithm and Clinical Prediction Rule for Diagnosis of Bone Stress Injuries.
Nye NS, Covey CJ, Pawlak M, Olsen C, Boden BP, Beutler AI
Sports Health 2020 Sep/Oct;12(5):449-455. Epub 2020 Aug 7 doi: 10.1177/1941738120943540. PMID: 32762527Free PMC Article
Reporting standards of the Society for Vascular Surgery for thoracic outlet syndrome.
Illig KA, Donahue D, Duncan A, Freischlag J, Gelabert H, Johansen K, Jordan S, Sanders R, Thompson R
J Vasc Surg 2016 Sep;64(3):e23-35. doi: 10.1016/j.jvs.2016.04.039. PMID: 27565607
Fibrofog and fibromyalgia: a narrative review and implications for clinical practice.
Kravitz HM, Katz RS
Rheumatol Int 2015 Jul;35(7):1115-25. Epub 2015 Jan 13 doi: 10.1007/s00296-014-3208-7. PMID: 25583051
Cellulitis: diagnosis and management.
Bailey E, Kroshinsky D
Dermatol Ther 2011 Mar-Apr;24(2):229-39. doi: 10.1111/j.1529-8019.2011.01398.x. PMID: 21410612

Recent systematic reviews

Chest physiotherapy for pneumonia in adults.
Chen X, Jiang J, Wang R, Fu H, Lu J, Yang M
Cochrane Database Syst Rev 2022 Sep 6;9(9):CD006338. doi: 10.1002/14651858.CD006338.pub4. PMID: 36066373Free PMC Article
A systematic review and meta-analysis of risk factors and treatment choices in emphysematous pyelonephritis.
Desai R, Batura D
Int Urol Nephrol 2022 Apr;54(4):717-736. Epub 2022 Feb 1 doi: 10.1007/s11255-022-03131-6. PMID: 35103928
A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Aquatic exercise for the treatment of knee and hip osteoarthritis.
Bartels EM, Juhl CB, Christensen R, Hagen KB, Danneskiold-Samsøe B, Dagfinrud H, Lund H
Cochrane Database Syst Rev 2016 Mar 23;3(3):CD005523. doi: 10.1002/14651858.CD005523.pub3. PMID: 27007113Free PMC Article
Resistance exercise training for fibromyalgia.
Busch AJ, Webber SC, Richards RS, Bidonde J, Schachter CL, Schafer LA, Danyliw A, Sawant A, Dal Bello-Haas V, Rader T, Overend TJ
Cochrane Database Syst Rev 2013 Dec 20;2013(12):CD010884. doi: 10.1002/14651858.CD010884. PMID: 24362925Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...