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Aggravated Malignant Neoplasm

MedGen UID:
116015
•Concept ID:
C0236022
•
Neoplastic Process

Definition

A malignant neoplasm that shows clinical and/or pathologic progression. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAggravated Malignant Neoplasm

Professional guidelines

PubMed

Why primary obesity is a disease?
De Lorenzo A, Gratteri S, Gualtieri P, Cammarano A, Bertucci P, Di Renzo L
J Transl Med 2019 May 22;17(1):169. doi: 10.1186/s12967-019-1919-y. PMID: 31118060Free PMC Article
EAA clinical practice guidelines-gynecomastia evaluation and management.
Kanakis GA, Nordkap L, Bang AK, Calogero AE, Bártfai G, Corona G, Forti G, Toppari J, Goulis DG, Jørgensen N
Andrology 2019 Nov;7(6):778-793. Epub 2019 May 16 doi: 10.1111/andr.12636. PMID: 31099174
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article

Recent clinical studies

Etiology

Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Neutrophil extracellular traps promote metastasis in gastric cancer patients with postoperative abdominal infectious complications.
Xia X, Zhang Z, Zhu C, Ni B, Wang S, Yang S, Yu F, Zhao E, Li Q, Zhao G
Nat Commun 2022 Feb 23;13(1):1017. doi: 10.1038/s41467-022-28492-5. PMID: 35197446Free PMC Article
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article
Cancer-associated cachexia.
Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH
Nat Rev Dis Primers 2018 Jan 18;4:17105. doi: 10.1038/nrdp.2017.105. PMID: 29345251
Estrogen, Estrogen Receptor and Lung Cancer.
Hsu LH, Chu NM, Kao SH
Int J Mol Sci 2017 Aug 5;18(8) doi: 10.3390/ijms18081713. PMID: 28783064Free PMC Article

Diagnosis

Imaging in gynecomastia.
Billa E, Kanakis GA, Goulis DG
Andrology 2021 Sep;9(5):1444-1456. Epub 2021 Jun 10 doi: 10.1111/andr.13051. PMID: 34033252
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article
Cancer-associated cachexia.
Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH
Nat Rev Dis Primers 2018 Jan 18;4:17105. doi: 10.1038/nrdp.2017.105. PMID: 29345251
Brain Cancer: Implication to Disease, Therapeutic Strategies and Tumor Targeted Drug Delivery Approaches.
Shah V, Kochar P
Recent Pat Anticancer Drug Discov 2018;13(1):70-85. doi: 10.2174/1574892812666171129142023. PMID: 29189177
Cancer Symptom Cluster Management.
Kwekkeboom KL
Semin Oncol Nurs 2016 Nov;32(4):373-382. Epub 2016 Oct 24 doi: 10.1016/j.soncn.2016.08.004. PMID: 27789073Free PMC Article

Therapy

Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article
MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2.
Zhao L, Qi Y, Xu L, Tao X, Han X, Yin L, Peng J
Redox Biol 2018 May;15:284-296. Epub 2017 Dec 29 doi: 10.1016/j.redox.2017.12.013. PMID: 29304479Free PMC Article
Brain Cancer: Implication to Disease, Therapeutic Strategies and Tumor Targeted Drug Delivery Approaches.
Shah V, Kochar P
Recent Pat Anticancer Drug Discov 2018;13(1):70-85. doi: 10.2174/1574892812666171129142023. PMID: 29189177
Estrogen, Estrogen Receptor and Lung Cancer.
Hsu LH, Chu NM, Kao SH
Int J Mol Sci 2017 Aug 5;18(8) doi: 10.3390/ijms18081713. PMID: 28783064Free PMC Article

Prognosis

CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Mol Cancer 2022 Jun 30;21(1):140. doi: 10.1186/s12943-022-01608-7. PMID: 35773744Free PMC Article
Pan-cancer analysis reveals RIPK2 predicts prognosis and promotes immune therapy resistance via triggering cytotoxic T lymphocytes dysfunction.
Song J, Yang R, Wei R, Du Y, He P, Liu X
Mol Med 2022 May 4;28(1):47. doi: 10.1186/s10020-022-00475-8. PMID: 35508972Free PMC Article
lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/β-Catenin Pathway and Oncogenic Autophagy.
Wu Q, Ma J, Wei J, Meng W, Wang Y, Shi M
Mol Ther 2021 Mar 3;29(3):1258-1278. Epub 2020 Oct 15 doi: 10.1016/j.ymthe.2020.10.011. PMID: 33068778Free PMC Article
Brain Cancer: Implication to Disease, Therapeutic Strategies and Tumor Targeted Drug Delivery Approaches.
Shah V, Kochar P
Recent Pat Anticancer Drug Discov 2018;13(1):70-85. doi: 10.2174/1574892812666171129142023. PMID: 29189177
Estrogen, Estrogen Receptor and Lung Cancer.
Hsu LH, Chu NM, Kao SH
Int J Mol Sci 2017 Aug 5;18(8) doi: 10.3390/ijms18081713. PMID: 28783064Free PMC Article

Clinical prediction guides

NAFLD and HBV interplay - related mechanisms underlying liver disease progression.
Tourkochristou E, Assimakopoulos SF, Thomopoulos K, Marangos M, Triantos C
Front Immunol 2022;13:965548. Epub 2022 Dec 5 doi: 10.3389/fimmu.2022.965548. PMID: 36544761Free PMC Article
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Pan-cancer analysis reveals RIPK2 predicts prognosis and promotes immune therapy resistance via triggering cytotoxic T lymphocytes dysfunction.
Song J, Yang R, Wei R, Du Y, He P, Liu X
Mol Med 2022 May 4;28(1):47. doi: 10.1186/s10020-022-00475-8. PMID: 35508972Free PMC Article
Epigenetics of glioblastoma multiforme: From molecular mechanisms to therapeutic approaches.
Uddin MS, Mamun AA, Alghamdi BS, Tewari D, Jeandet P, Sarwar MS, Ashraf GM
Semin Cancer Biol 2022 Aug;83:100-120. Epub 2020 Dec 25 doi: 10.1016/j.semcancer.2020.12.015. PMID: 33370605
M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma.
Zuo X, Chen Z, Gao W, Zhang Y, Wang J, Wang J, Cao M, Cai J, Wu J, Wang X
J Hematol Oncol 2020 Jan 8;13(1):5. doi: 10.1186/s13045-019-0839-x. PMID: 31915027Free PMC Article

Recent systematic reviews

Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review.
Ruze R, Song J, Yin X, Chen Y, Xu R, Wang C, Zhao Y
Signal Transduct Target Ther 2023 Mar 24;8(1):139. doi: 10.1038/s41392-023-01376-w. PMID: 36964133Free PMC Article
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Green tea promotes weight loss in women with polycystic ovary syndrome: Systematic review and meta-analysis.
Colonetti L, Grande AJ, Toreti IR, Ceretta LB, da Rosa MI, Colonetti T
Nutr Res 2022 Aug;104:1-9. Epub 2022 Mar 27 doi: 10.1016/j.nutres.2022.03.009. PMID: 35504067
Association between serum amyloid A levels and cancers: a systematic review and meta-analysis.
Zhou J, Sheng J, Fan Y, Zhu X, Tao Q, He Y, Wang S
Postgrad Med J 2018 Sep;94(1115):499-507. Epub 2018 Oct 19 doi: 10.1136/postgradmedj-2018-136004. PMID: 30341230
Ectopic ACTH syndrome.
Isidori AM, Lenzi A
Arq Bras Endocrinol Metabol 2007 Nov;51(8):1217-25. doi: 10.1590/s0004-27302007000800007. PMID: 18209859

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