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Aggravated Malignant Neoplasm

MedGen UID:
116015
•Concept ID:
C0236022
•
Neoplastic Process

Definition

A malignant neoplasm that shows clinical and/or pathologic progression. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAggravated Malignant Neoplasm

Professional guidelines

PubMed

Why primary obesity is a disease?
De Lorenzo A, Gratteri S, Gualtieri P, Cammarano A, Bertucci P, Di Renzo L
J Transl Med 2019 May 22;17(1):169. doi: 10.1186/s12967-019-1919-y. PMID: 31118060Free PMC Article
EAA clinical practice guidelines-gynecomastia evaluation and management.
Kanakis GA, Nordkap L, Bang AK, Calogero AE, Bártfai G, Corona G, Forti G, Toppari J, Goulis DG, Jørgensen N
Andrology 2019 Nov;7(6):778-793. Epub 2019 May 16 doi: 10.1111/andr.12636. PMID: 31099174
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article

Recent clinical studies

Etiology

NAFLD and HBV interplay - related mechanisms underlying liver disease progression.
Tourkochristou E, Assimakopoulos SF, Thomopoulos K, Marangos M, Triantos C
Front Immunol 2022;13:965548. Epub 2022 Dec 5 doi: 10.3389/fimmu.2022.965548. PMID: 36544761Free PMC Article
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Neutrophil extracellular traps promote metastasis in gastric cancer patients with postoperative abdominal infectious complications.
Xia X, Zhang Z, Zhu C, Ni B, Wang S, Yang S, Yu F, Zhao E, Li Q, Zhao G
Nat Commun 2022 Feb 23;13(1):1017. doi: 10.1038/s41467-022-28492-5. PMID: 35197446Free PMC Article
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article
Cancer-associated cachexia.
Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH
Nat Rev Dis Primers 2018 Jan 18;4:17105. doi: 10.1038/nrdp.2017.105. PMID: 29345251

Diagnosis

Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review.
Ruze R, Song J, Yin X, Chen Y, Xu R, Wang C, Zhao Y
Signal Transduct Target Ther 2023 Mar 24;8(1):139. doi: 10.1038/s41392-023-01376-w. PMID: 36964133Free PMC Article
Imaging in gynecomastia.
Billa E, Kanakis GA, Goulis DG
Andrology 2021 Sep;9(5):1444-1456. Epub 2021 Jun 10 doi: 10.1111/andr.13051. PMID: 34033252
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article
Cancer-associated cachexia.
Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH
Nat Rev Dis Primers 2018 Jan 18;4:17105. doi: 10.1038/nrdp.2017.105. PMID: 29345251
Gastric carcinogenesis.
Bornschein J, Malfertheiner P
Langenbecks Arch Surg 2011 Aug;396(6):729-42. Epub 2011 May 25 doi: 10.1007/s00423-011-0810-y. PMID: 21611816

Therapy

Effectiveness of Aerobic Exercise and Tai Chi Interventions on Sleep Quality in Patients With Advanced Lung Cancer: A Randomized Clinical Trial.
Takemura N, Cheung DST, Fong DYT, Lee AWM, Lam TC, Ho JC, Kam TY, Chik JYK, Lin CC
JAMA Oncol 2024 Feb 1;10(2):176-184. doi: 10.1001/jamaoncol.2023.5248. PMID: 38060250Free PMC Article
Immunotherapy for hepatocellular carcinoma: Current status and future perspectives.
Mandlik DS, Mandlik SK, Choudhary HB
World J Gastroenterol 2023 Feb 14;29(6):1054-1075. doi: 10.3748/wjg.v29.i6.1054. PMID: 36844141Free PMC Article
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Microenvironment-driven sequential ferroptosis, photodynamic therapy, and chemotherapy for targeted breast cancer therapy by a cancer-cell-membrane-coated nanoscale metal-organic framework.
Pan WL, Tan Y, Meng W, Huang NH, Zhao YB, Yu ZQ, Huang Z, Zhang WH, Sun B, Chen JX
Biomaterials 2022 Apr;283:121449. Epub 2022 Mar 1 doi: 10.1016/j.biomaterials.2022.121449. PMID: 35247637
Cancer-associated stroke: Pathophysiology, detection and management (Review).
Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A
Int J Oncol 2019 Mar;54(3):779-796. Epub 2019 Jan 2 doi: 10.3892/ijo.2019.4669. PMID: 30628661Free PMC Article

Prognosis

Immunotherapy for hepatocellular carcinoma: Current status and future perspectives.
Mandlik DS, Mandlik SK, Choudhary HB
World J Gastroenterol 2023 Feb 14;29(6):1054-1075. doi: 10.3748/wjg.v29.i6.1054. PMID: 36844141Free PMC Article
Research progress on tumor hypoxia-associative nanomedicine.
Xu XX, Chen SY, Yi NB, Li X, Chen SL, Lei Z, Cheng DB, Sun T
J Control Release 2022 Oct;350:829-840. Epub 2022 Sep 13 doi: 10.1016/j.jconrel.2022.09.003. PMID: 36100192
CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.
Yao B, Zhang Q, Yang Z, An F, Nie H, Wang H, Yang C, Sun J, Chen K, Zhou J, Bai B, Gu S, Zhao W, Zhan Q
Mol Cancer 2022 Jun 30;21(1):140. doi: 10.1186/s12943-022-01608-7. PMID: 35773744Free PMC Article
lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/β-Catenin Pathway and Oncogenic Autophagy.
Wu Q, Ma J, Wei J, Meng W, Wang Y, Shi M
Mol Ther 2021 Mar 3;29(3):1258-1278. Epub 2020 Oct 15 doi: 10.1016/j.ymthe.2020.10.011. PMID: 33068778Free PMC Article
Nickel carcinogenesis.
Kasprzak KS, Sunderman FW Jr, Salnikow K
Mutat Res 2003 Dec 10;533(1-2):67-97. doi: 10.1016/j.mrfmmm.2003.08.021. PMID: 14643413

Clinical prediction guides

NAFLD and HBV interplay - related mechanisms underlying liver disease progression.
Tourkochristou E, Assimakopoulos SF, Thomopoulos K, Marangos M, Triantos C
Front Immunol 2022;13:965548. Epub 2022 Dec 5 doi: 10.3389/fimmu.2022.965548. PMID: 36544761Free PMC Article
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Epigenetics of glioblastoma multiforme: From molecular mechanisms to therapeutic approaches.
Uddin MS, Mamun AA, Alghamdi BS, Tewari D, Jeandet P, Sarwar MS, Ashraf GM
Semin Cancer Biol 2022 Aug;83:100-120. Epub 2020 Dec 25 doi: 10.1016/j.semcancer.2020.12.015. PMID: 33370605
Gastric carcinogenesis.
Bornschein J, Malfertheiner P
Langenbecks Arch Surg 2011 Aug;396(6):729-42. Epub 2011 May 25 doi: 10.1007/s00423-011-0810-y. PMID: 21611816
Nickel carcinogenesis.
Kasprzak KS, Sunderman FW Jr, Salnikow K
Mutat Res 2003 Dec 10;533(1-2):67-97. doi: 10.1016/j.mrfmmm.2003.08.021. PMID: 14643413

Recent systematic reviews

Financial toxicity experienced by patients with breast cancer-related lymphedema: a systematic review.
Bian J, Shen A, Yang W, Zhang L, Qiang W
Support Care Cancer 2023 May 27;31(6):354. doi: 10.1007/s00520-023-07800-9. PMID: 37237237
Mechanisms of obesity- and diabetes mellitus-related pancreatic carcinogenesis: a comprehensive and systematic review.
Ruze R, Song J, Yin X, Chen Y, Xu R, Wang C, Zhao Y
Signal Transduct Target Ther 2023 Mar 24;8(1):139. doi: 10.1038/s41392-023-01376-w. PMID: 36964133Free PMC Article
Nutritional Interventions to Improve Cachexia Outcomes in Cancer-A Systematic Review.
Braha A, Albai A, Timar B, Negru Ș, Sorin S, Roman D, Popovici D
Medicina (Kaunas) 2022 Jul 21;58(7) doi: 10.3390/medicina58070966. PMID: 35888685Free PMC Article
Association between serum amyloid A levels and cancers: a systematic review and meta-analysis.
Zhou J, Sheng J, Fan Y, Zhu X, Tao Q, He Y, Wang S
Postgrad Med J 2018 Sep;94(1115):499-507. Epub 2018 Oct 19 doi: 10.1136/postgradmedj-2018-136004. PMID: 30341230
Ectopic ACTH syndrome.
Isidori AM, Lenzi A
Arq Bras Endocrinol Metabol 2007 Nov;51(8):1217-25. doi: 10.1590/s0004-27302007000800007. PMID: 18209859

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