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Brain hemangioma

MedGen UID:
116075
•Concept ID:
C0238814
•
Disease or Syndrome
Synonyms: Brain Angioma; brain angioma; Brain Hemangioma; brain hemangioma
 
Monarch Initiative: MONDO:0003428

Definition

A hemangioma arising from the brain. [from NCI]

Professional guidelines

PubMed

Port-wine Birthmarks: Update on Diagnosis, Risk Assessment for Sturge-Weber Syndrome, and Management.
Poliner A, Fernandez Faith E, Blieden L, Kelly KM, Metry D
Pediatr Rev 2022 Sep 1;43(9):507-516. doi: 10.1542/pir.2021-005437. PMID: 36045161
Consensus Statement for the Management and Treatment of Sturge-Weber Syndrome: Neurology, Neuroimaging, and Ophthalmology Recommendations.
Sabeti S, Ball KL, Bhattacharya SK, Bitrian E, Blieden LS, Brandt JD, Burkhart C, Chugani HT, Falchek SJ, Jain BG, Juhasz C, Loeb JA, Luat A, Pinto A, Segal E, Salvin J, Kelly KM
Pediatr Neurol 2021 Aug;121:59-66. Epub 2021 May 6 doi: 10.1016/j.pediatrneurol.2021.04.013. PMID: 34153815Free PMC Article
Consensus Statement for the Management and Treatment of Port-Wine Birthmarks in Sturge-Weber Syndrome.
Sabeti S, Ball KL, Burkhart C, Eichenfield L, Fernandez Faith E, Frieden IJ, Geronemus R, Gupta D, Krakowski AC, Levy ML, Metry D, Nelson JS, Tollefson MM, Kelly KM
JAMA Dermatol 2021 Jan 1;157(1):98-104. doi: 10.1001/jamadermatol.2020.4226. PMID: 33175124Free PMC Article

Recent clinical studies

Etiology

Phacomatosis pigmentovascularis of cesioflammea type in 7 patients: combination of ocular pigmentation (melanocytosis or melanosis) and nevus flammeus with risk for melanoma.
Shields CL, Kligman BE, Suriano M, Viloria V, Iturralde JC, Shields MV, Say EA, Shields JA
Arch Ophthalmol 2011 Jun;129(6):746-50. doi: 10.1001/archophthalmol.2011.135. PMID: 21670341

Diagnosis

High resolution mass spectrometry provides novel insights into the ganglioside pattern of brain cavernous hemangioma.
Ica R, Simulescu A, Sarbu M, Munteanu CVA, Vukelić Ž, Zamfir AD
Anal Biochem 2020 Nov 15;609:113976. Epub 2020 Sep 26 doi: 10.1016/j.ab.2020.113976. PMID: 32987010
Phacomatosis pigmentovascularis of cesioflammea type in 7 patients: combination of ocular pigmentation (melanocytosis or melanosis) and nevus flammeus with risk for melanoma.
Shields CL, Kligman BE, Suriano M, Viloria V, Iturralde JC, Shields MV, Say EA, Shields JA
Arch Ophthalmol 2011 Jun;129(6):746-50. doi: 10.1001/archophthalmol.2011.135. PMID: 21670341
Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry.
Schiopu C, Flangea C, Capitan F, Serb A, Vukelić Z, Kalanj-Bognar S, Sisu E, Przybylski M, Zamfir AD
Anal Bioanal Chem 2009 Dec;395(8):2465-77. Epub 2009 Oct 16 doi: 10.1007/s00216-009-3188-8. PMID: 19841910
A rare coexistence of a multicentric hepatic hemangioendothelioma with a large brain hemangioma in a preterm infant.
Bar-Sever Z, Horev G, Lubin E, Kornreich L, Naor N, Ziv N, Shimoni A, Grunebaum M
Pediatr Radiol 1994;24(2):141-2. doi: 10.1007/BF02020175. PMID: 8078719

Therapy

Inhibition of intracranial hemangioma growth and hemorrhage by TNFSF15.
Yang GL, Han Z, Xiong J, Wang S, Wei H, Qin TT, Xiao H, Liu Y, Xu LX, Qi JW, Zhang ZS, Jiang R, Zhang J, Li LY
FASEB J 2019 Sep;33(9):10505-10514. Epub 2019 Jun 26 doi: 10.1096/fj.201802758RRR. PMID: 31242765

Prognosis

Inhibition of intracranial hemangioma growth and hemorrhage by TNFSF15.
Yang GL, Han Z, Xiong J, Wang S, Wei H, Qin TT, Xiao H, Liu Y, Xu LX, Qi JW, Zhang ZS, Jiang R, Zhang J, Li LY
FASEB J 2019 Sep;33(9):10505-10514. Epub 2019 Jun 26 doi: 10.1096/fj.201802758RRR. PMID: 31242765
Phacomatosis pigmentovascularis of cesioflammea type in 7 patients: combination of ocular pigmentation (melanocytosis or melanosis) and nevus flammeus with risk for melanoma.
Shields CL, Kligman BE, Suriano M, Viloria V, Iturralde JC, Shields MV, Say EA, Shields JA
Arch Ophthalmol 2011 Jun;129(6):746-50. doi: 10.1001/archophthalmol.2011.135. PMID: 21670341

Clinical prediction guides

Phacomatosis pigmentovascularis of cesioflammea type in 7 patients: combination of ocular pigmentation (melanocytosis or melanosis) and nevus flammeus with risk for melanoma.
Shields CL, Kligman BE, Suriano M, Viloria V, Iturralde JC, Shields MV, Say EA, Shields JA
Arch Ophthalmol 2011 Jun;129(6):746-50. doi: 10.1001/archophthalmol.2011.135. PMID: 21670341
Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry.
Schiopu C, Flangea C, Capitan F, Serb A, Vukelić Z, Kalanj-Bognar S, Sisu E, Przybylski M, Zamfir AD
Anal Bioanal Chem 2009 Dec;395(8):2465-77. Epub 2009 Oct 16 doi: 10.1007/s00216-009-3188-8. PMID: 19841910

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