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Neoplasm of thorax

MedGen UID:
11793
•Concept ID:
C0039981
•
Neoplastic Process
Synonyms: Neoplasm, Thoracic; Neoplasms, Thoracic; Thoracic Neoplasm; Thoracic Neoplasms
SNOMED CT: Neoplasm of thorax (255058005); Tumor of thorax (255058005)
 
Monarch Initiative: MONDO:0021350

Definition

A benign or malignant, primary or metastatic neoplasm involving the tissues of the thorax. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm of thorax

Professional guidelines

PubMed

SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection.
Wang Q, Gümüş ZH, Colarossi C, Memeo L, Wang X, Kong CY, Boffetta P
J Thorac Oncol 2023 Jan;18(1):31-46. Epub 2022 Oct 12 doi: 10.1016/j.jtho.2022.10.002. PMID: 36243387Free PMC Article
Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management.
McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX
Lancet Respir Med 2021 Nov;9(11):1313-1327. Epub 2021 Aug 27 doi: 10.1016/S2213-2600(21)00228-9. PMID: 34461049
Non-Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment.
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236

Recent clinical studies

Etiology

Diagnosis of thoracic SMARCA4-deficient undifferentiated tumor in cytology.
Kezlarian B, Montecalvo J, Bodd FM, Chang JC, Riedel E, White C, Rekhtman N, Sauter JL
Cancer Cytopathol 2023 Aug;131(8):526-534. Epub 2023 Jun 6 doi: 10.1002/cncy.22709. PMID: 37278102
Evaluation of Risk for Thoracic Surgery.
Brunelli A, Gooseman MR, Pompili C
Surg Oncol Clin N Am 2020 Oct;29(4):497-508. Epub 2020 Jul 21 doi: 10.1016/j.soc.2020.06.001. PMID: 32883454
Thoracic Manifestations of Genitourinary Neoplasms and Treatment-related Complications.
Stowell JT, Betancourt-Cuellar SL, Carter BW, Wu CC, Walker CM
J Thorac Imaging 2019 May;34(3):W36-W48. doi: 10.1097/RTI.0000000000000382. PMID: 31009398
Primary Extranodal Lymphoma of the Thorax.
Kligerman SJ, Franks TJ, Galvin JR
Radiol Clin North Am 2016 Jul;54(4):673-87. doi: 10.1016/j.rcl.2016.03.002. PMID: 27265602
Intrathoracic neurogenic tumors.
Bicakcioglu P, Demirag F, Yazicioglu A, Aydogdu K, Kaya S, Karaoglanoglu N
Thorac Cardiovasc Surg 2014 Mar;62(2):147-52. Epub 2013 Apr 23 doi: 10.1055/s-0033-1343898. PMID: 23613143

Diagnosis

Diagnosis of thoracic SMARCA4-deficient undifferentiated tumor in cytology.
Kezlarian B, Montecalvo J, Bodd FM, Chang JC, Riedel E, White C, Rekhtman N, Sauter JL
Cancer Cytopathol 2023 Aug;131(8):526-534. Epub 2023 Jun 6 doi: 10.1002/cncy.22709. PMID: 37278102
Progress in the Diagnosis and Treatment of Thoracic Malignancies Continues Unabated.
Adjei AA
J Thorac Oncol 2019 May;14(5):757. doi: 10.1016/j.jtho.2019.02.022. PMID: 31027737
MR Imaging of Primary Chest Wall Neoplasms.
Bueno J, Lichtenberger JP 3rd, Rauch G, Carter BW
Top Magn Reson Imaging 2018 Apr;27(2):83-93. doi: 10.1097/RMR.0000000000000164. PMID: 29613963
Primary Extranodal Lymphoma of the Thorax.
Kligerman SJ, Franks TJ, Galvin JR
Radiol Clin North Am 2016 Jul;54(4):673-87. doi: 10.1016/j.rcl.2016.03.002. PMID: 27265602
Chest wall lesions.
Watt AJ
Paediatr Respir Rev 2002 Dec;3(4):328-38. PMID: 12457604

Therapy

HERTHENA-Lung01: a phase II study of patritumab deruxtecan (HER3-DXd) in previously treated metastatic EGFR-mutated NSCLC.
Yu HA, Yang JC, Hayashi H, Goto Y, Felip E, Reck M, Vigliotti M, Dong Q, Cantero F, Fan PD, Kanai M, Sternberg DW, Jänne PA
Future Oncol 2023 Jun;19(19):1319-1329. Epub 2023 May 22 doi: 10.2217/fon-2022-1250. PMID: 37212796
Malignant pleural mesothelioma: recent developments.
Sinn K, Mosleh B, Hoda MA
Curr Opin Oncol 2021 Jan;33(1):80-86. doi: 10.1097/CCO.0000000000000697. PMID: 33186182
EGFR-mutant NSCLC: emerging novel drugs.
Ye L, Chen X, Zhou F
Curr Opin Oncol 2021 Jan;33(1):87-94. doi: 10.1097/CCO.0000000000000701. PMID: 33122578
An overview of the design and conduct of the BATTLE trials.
Liu S, Lee JJ
Chin Clin Oncol 2015 Sep;4(3):33. doi: 10.3978/j.issn.2304-3865.2015.06.07. PMID: 26408300
Lung cancer screening: advantages, controversies, and applications.
Nanavaty P, Alvarez MS, Alberts WM
Cancer Control 2014 Jan;21(1):9-14. doi: 10.1177/107327481402100102. PMID: 24357736

Prognosis

Forecasting lung cancer incidence, mortality, and prevalence to year 2030.
Jakobsen E, Olsen KE, Bliddal M, Hornbak M, Persson GF, Green A
BMC Cancer 2021 Sep 3;21(1):985. doi: 10.1186/s12885-021-08696-6. PMID: 34479490Free PMC Article
High-dose versus standard-dose twice-daily thoracic radiotherapy for patients with limited stage small-cell lung cancer: an open-label, randomised, phase 2 trial.
Grønberg BH, Killingberg KT, Fløtten Ø, Brustugun OT, Hornslien K, Madebo T, Langer SW, Schytte T, Nyman J, Risum S, Tsakonas G, Engleson J, Halvorsen TO
Lancet Oncol 2021 Mar;22(3):321-331. doi: 10.1016/S1470-2045(20)30742-7. PMID: 33662285
The Effect of Advances in Lung-Cancer Treatment on Population Mortality.
Howlader N, Forjaz G, Mooradian MJ, Meza R, Kong CY, Cronin KA, Mariotto AB, Lowy DR, Feuer EJ
N Engl J Med 2020 Aug 13;383(7):640-649. doi: 10.1056/NEJMoa1916623. PMID: 32786189Free PMC Article
Lung cancer mortality reduction by LDCT screening-Results from the randomized German LUSI trial.
Becker N, Motsch E, Trotter A, Heussel CP, Dienemann H, Schnabel PA, Kauczor HU, Maldonado SG, Miller AB, Kaaks R, Delorme S
Int J Cancer 2020 Mar 15;146(6):1503-1513. Epub 2019 Jun 20 doi: 10.1002/ijc.32486. PMID: 31162856
Malignant pleural mesothelioma.
Boutin C, Schlesser M, Frenay C, Astoul P
Eur Respir J 1998 Oct;12(4):972-81. doi: 10.1183/09031936.98.12040972. PMID: 9817178

Clinical prediction guides

Surgical treatment of elastofibroma dorsi. Personal experience and a review of the literature.
Lucandri G, Pende V, Lucchese S, Fassari A, Campagna D, Fiori G, Mazzocchi P, Lirici MM, Santoro E
Ann Ital Chir 2023;94:99-105. PMID: 36350282
Complete resections of giant thorax masses and experienced difficulties.
Yenigün BM, Yüksel C, İbrahimov F, Yücemen U, Gürsoy Çoruh A, Kahya Y, Kocaman G, Özkan M, Enön S, Kayı Cangır A
Tuberk Toraks 2020 Sep;68(3):278-284. doi: 10.5578/tt.69670. PMID: 33295726
Advanced-Stage Non-Small Cell Lung Cancer: Advances in Thoracic Oncology 2018.
Remon J, Ahn MJ, Girard N, Johnson M, Kim DW, Lopes G, Pillai RN, Solomon B, Villacampa G, Zhou Q
J Thorac Oncol 2019 Jul;14(7):1134-1155. Epub 2019 Apr 16 doi: 10.1016/j.jtho.2019.03.022. PMID: 31002952
Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.
Brunelli A, Kim AW, Berger KI, Addrizzo-Harris DJ
Chest 2013 May;143(5 Suppl):e166S-e190S. doi: 10.1378/chest.12-2395. PMID: 23649437
DNA methylation in thoracic neoplasms.
Chen C, Yin N, Yin B, Lu Q
Cancer Lett 2011 Feb 1;301(1):7-16. Epub 2010 Nov 18 doi: 10.1016/j.canlet.2010.10.017. PMID: 21087818

Recent systematic reviews

Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review.
Prelaj A, Miskovic V, Zanitti M, Trovo F, Genova C, Viscardi G, Rebuzzi SE, Mazzeo L, Provenzano L, Kosta S, Favali M, Spagnoletti A, Castelo-Branco L, Dolezal J, Pearson AT, Lo Russo G, Proto C, Ganzinelli M, Giani C, Ambrosini E, Turajlic S, Au L, Koopman M, Delaloge S, Kather JN, de Braud F, Garassino MC, Pentheroudakis G, Spencer C, Pedrocchi ALG
Ann Oncol 2024 Jan;35(1):29-65. Epub 2023 Oct 23 doi: 10.1016/j.annonc.2023.10.125. PMID: 37879443
Surgical, Radiation, and Systemic Treatments of Patients With Thymic Epithelial Tumors: A Systematic Review.
Falkson CB, Vella ET, Ellis PM, Maziak DE, Ung YC, Yu E
J Thorac Oncol 2023 Mar;18(3):299-312. Epub 2022 Nov 4 doi: 10.1016/j.jtho.2022.10.016. PMID: 36343922
Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality.
Bonney A, Malouf R, Marchal C, Manners D, Fong KM, Marshall HM, Irving LB, Manser R
Cochrane Database Syst Rev 2022 Aug 3;8(8):CD013829. doi: 10.1002/14651858.CD013829.pub2. PMID: 35921047Free PMC Article
Role of Beta-Carotene in Lung Cancer Primary Chemoprevention: A Systematic Review with Meta-Analysis and Meta-Regression.
Kordiak J, Bielec F, Jabłoński S, Pastuszak-Lewandoska D
Nutrients 2022 Mar 24;14(7) doi: 10.3390/nu14071361. PMID: 35405977Free PMC Article
NSCLC Immunotherapy Efficacy and Antibiotic Use: A Systematic Review and Meta-Analysis.
Lurienne L, Cervesi J, Duhalde L, de Gunzburg J, Andremont A, Zalcman G, Buffet R, Bandinelli PA
J Thorac Oncol 2020 Jul;15(7):1147-1159. Epub 2020 Mar 12 doi: 10.1016/j.jtho.2020.03.002. PMID: 32173463

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