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Pulmonary tuberculosis

MedGen UID:
11947
Concept ID:
C0041327
Disease or Syndrome
Synonyms: Consumption, Pulmonary; Consumptions, Pulmonary; Phthises, Pulmonary; Phthisis, Pulmonary; Pulmonary Consumption; Pulmonary Consumptions; Pulmonary Phthises; Pulmonary Phthisis; Pulmonary Tuberculoses; Pulmonary Tuberculosis; Tuberculoses, Pulmonary; Tuberculosis, Pulmonary
SNOMED CT: PTB - Pulmonary tuberculosis (154283005); TB - Pulmonary tuberculosis (154283005); Pulmonary tuberculosis (154283005); Tuberculosis of respiratory system (700272008); Respiratory tuberculosis (700272008)
 
HPO: HP:0032262
Monarch Initiative: MONDO:0006052

Definition

A lung infection by Mycobacterium tuberculosis a slightly curved non-motile, aerobic, non-capsulated and non-spore forming strains of mycobacteria. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary tuberculosis

Conditions with this feature

X-linked Mendelian susceptibility to mycobacterial diseases due to CYBB deficiency
MedGen UID:
370369
Concept ID:
C1970859
Disease or Syndrome
IMD34 results in predisposition to infections by poorly virulent mycobacteria, such as bacillus Calmette-Guerin (BCG) vaccines and nontuberculous environmental bacteria. Affected individuals are also susceptible to the more virulent species Mycobacterium tuberculosis (Bustamante et al., 2007).

Professional guidelines

PubMed

Tendolkar MS, Tyagi R, Handa A
Indian J Tuberc 2021 Oct;68(4):510-515. Epub 2021 Jul 7 doi: 10.1016/j.ijtb.2021.07.002. PMID: 34752322
Nachiappan AC, Rahbar K, Shi X, Guy ES, Mortani Barbosa EJ Jr, Shroff GS, Ocazionez D, Schlesinger AE, Katz SI, Hammer MM
Radiographics 2017 Jan-Feb;37(1):52-72. doi: 10.1148/rg.2017160032. PMID: 28076011
Koh WJ, Kwon OJ, Lee KS
J Korean Med Sci 2005 Dec;20(6):913-25. doi: 10.3346/jkms.2005.20.6.913. PMID: 16361797Free PMC Article

Recent clinical studies

Etiology

George JT, Miraclin AT, Sathyendra S, Michael JS, Prasad J, Rebekah G
Int J Mycobacteriol 2022 Oct-Dec;11(4):400-406. doi: 10.4103/ijmy.ijmy_154_22. PMID: 36510925
Yadav V, Sharma JB, Kriplani A, Bhatla N, Kachhawa G, Mahey R, Kumari R
Indian J Tuberc 2022 Jul;69(3):305-310. Epub 2021 Jan 7 doi: 10.1016/j.ijtb.2020.12.006. PMID: 35760479
Jindal SK
Indian J Tuberc 2022 Apr;69(2):131-133. Epub 2021 Oct 4 doi: 10.1016/j.ijtb.2021.09.013. PMID: 35379391
Chierakul N, Boonsuk J, Muangman N, Totanarungroj K
J Med Assoc Thai 2016 Jun;99(6):697-701. PMID: 29901318
Sheer TA, Coyle WJ
Curr Gastroenterol Rep 2003 Aug;5(4):273-8. doi: 10.1007/s11894-003-0063-1. PMID: 12864956

Diagnosis

Tendolkar MS, Tyagi R, Handa A
Indian J Tuberc 2021 Oct;68(4):510-515. Epub 2021 Jul 7 doi: 10.1016/j.ijtb.2021.07.002. PMID: 34752322
Neogi S, Mukhopadhyay P, Sarkar N, Datta PK, Basu M, Ghosh S
Endocr Pract 2021 Jun;27(6):601-606. Epub 2020 Dec 14 doi: 10.1016/j.eprac.2020.11.012. PMID: 33645514
Chierakul N, Boonsuk J, Muangman N, Totanarungroj K
J Med Assoc Thai 2016 Jun;99(6):697-701. PMID: 29901318
Rozenshtein A, Hao F, Starc MT, Pearson GD
AJR Am J Roentgenol 2015 May;204(5):974-8. doi: 10.2214/AJR.14.13483. PMID: 25905930
Naidoo R
Curr Opin Pulm Med 2008 May;14(3):254-9. doi: 10.1097/MCP.0b013e3282f76417. PMID: 18427250

Therapy

Berry C, du Cros P, Fielding K, Gajewski S, Kazounis E, McHugh TD, Merle C, Motta I, Moore DAJ, Nyang'wa BT
Trials 2022 Jun 13;23(1):484. doi: 10.1186/s13063-022-06331-8. PMID: 35698158Free PMC Article
McAnaw SE, Hesseling AC, Seddon JA, Dooley KE, Garcia-Prats AJ, Kim S, Jenkins HE, Schaaf HS, Sterling TR, Horsburgh CR
Int J Infect Dis 2017 Mar;56:194-199. Epub 2016 Dec 9 doi: 10.1016/j.ijid.2016.11.423. PMID: 27955992Free PMC Article
O'Shea MK, McShane H
Hum Vaccin Immunother 2016 May 3;12(5):1177-87. Epub 2016 Jan 25 doi: 10.1080/21645515.2015.1134407. PMID: 26810964Free PMC Article
Goulooze SC, Cohen AF, Rissmann R
Br J Clin Pharmacol 2015 Aug;80(2):182-4. Epub 2015 Jul 2 doi: 10.1111/bcp.12613. PMID: 25702772Free PMC Article
Khanna BK, Gupta VP, Singh MP
Tubercle 1984 Sep;65(3):195-9. doi: 10.1016/0041-3879(84)90075-8. PMID: 6207648

Prognosis

Bhargava A, Bhargava M, Meher A, Benedetti A, Velayutham B, Sai Teja G, Watson B, Barik G, Pathak RR, Prasad R, Dayal R, Madhukeshwar AK, Chadha V, Pai M, Joshi R, Menzies D, Swaminathan S
Lancet 2023 Aug 19;402(10402):627-640. Epub 2023 Aug 8 doi: 10.1016/S0140-6736(23)01231-X. PMID: 37567200
Dong Z, Wang QQ, Yu SC, Huang F, Liu JJ, Yao HY, Zhao YL
Infect Dis Poverty 2022 Jul 28;11(1):85. doi: 10.1186/s40249-022-01009-4. PMID: 35902982Free PMC Article
Yang DL, Li W, Pan MH, Su HX, Li YN, Tang MY, Song XK
PLoS One 2022;17(5):e0268472. Epub 2022 May 24 doi: 10.1371/journal.pone.0268472. PMID: 35609085Free PMC Article
Garg RK
Acta Neurol Scand 2010 Aug;122(2):75-90. Epub 2010 Jan 6 doi: 10.1111/j.1600-0404.2009.01316.x. PMID: 20055767
Bai KJ, Wu IH, Yu MC, Chiang IH, Chiang CY, Lin TP, Lee YC, Luh KT
Respirology 1998 Dec;3(4):261-6. doi: 10.1111/j.1440-1843.1998.tb00132.x. PMID: 10201053

Clinical prediction guides

Howard-Jones AR, Marais BJ
Curr Opin Pediatr 2020 Jun;32(3):395-404. doi: 10.1097/MOP.0000000000000897. PMID: 32374579
Li T, Shi T, Sun Y, Zhou K, Huang Z, Wang P, Luo M, Nie X, Yang G, Chen Y, Chen Y
BMC Infect Dis 2020 Apr 22;20(1):303. doi: 10.1186/s12879-020-05036-0. PMID: 32321447Free PMC Article
Niyonkuru A, Chen X, Bakari KH, Wimalarathne DN, Bouhari A, Arnous MMR, Lan X
Cancer Med 2020 Feb;9(3):931-942. Epub 2019 Dec 13 doi: 10.1002/cam4.2770. PMID: 31837121Free PMC Article
Wang H, Ji XB, Li CW, Lu HW, Mao B, Liang S, Cheng KB, Bai JW, Martinez-Garcia MA, Xu JF
Clin Respir J 2018 Aug;12(8):2346-2353. doi: 10.1111/crj.12911. PMID: 29790656
Chan ED, Heifets L, Iseman MD
Tuber Lung Dis 2000;80(3):131-40. doi: 10.1054/tuld.2000.0243. PMID: 10970761

Recent systematic reviews

Sossen B, Richards AS, Heinsohn T, Frascella B, Balzarini F, Oradini-Alacreu A, Odone A, Rogozinska E, Häcker B, Cobelens F, Kranzer K, Houben RMGJ, Esmail H
Lancet Respir Med 2023 Apr;11(4):367-379. Epub 2023 Mar 23 doi: 10.1016/S2213-2600(23)00097-8. PMID: 36966795
Igbokwe V, Ruby LC, Sultanli A, Bélard S
Lancet Infect Dis 2023 Apr;23(4):e138-e150. doi: 10.1016/S1473-3099(23)00004-X. PMID: 36963920
Natarajan A, Beena PM, Devnikar AV, Mali S
Indian J Tuberc 2020 Jul;67(3):295-311. Epub 2020 Feb 28 doi: 10.1016/j.ijtb.2020.02.005. PMID: 32825856
Saktiawati AMI, Putera DD, Setyawan A, Mahendradhata Y, van der Werf TS
EBioMedicine 2019 Aug;46:202-214. Epub 2019 Aug 8 doi: 10.1016/j.ebiom.2019.07.056. PMID: 31401197Free PMC Article
Steingart KR, Schiller I, Horne DJ, Pai M, Boehme CC, Dendukuri N
Cochrane Database Syst Rev 2014 Jan 21;2014(1):CD009593. doi: 10.1002/14651858.CD009593.pub3. PMID: 24448973Free PMC Article

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