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Neoplasm of the urethra

MedGen UID:
12014
•Concept ID:
C0041971
•
Neoplastic Process
Synonym: Urethra neoplasm
SNOMED CT: Neoplasm of urethra (126883004); Tumor of urethra (126883004); Urethral tumor (126883004)
 
HPO: HP:0100517
Monarch Initiative: MONDO:0021239

Definition

The presence of a neoplasm of the urethra. [from HPO]

Professional guidelines

PubMed

Evaluation and management of urethral and periurethral masses in women.
Zuo SW, Napoe GS
Curr Opin Obstet Gynecol 2023 Dec 1;35(6):517-524. Epub 2023 Aug 29 doi: 10.1097/GCO.0000000000000914. PMID: 37678190
Progress in the treatment of urethral adenocarcinoma.
Guo J, Liang X, Zheng Y, Ma J
J Cancer Res Clin Oncol 2023 Jun;149(6):2693-2698. Epub 2022 Nov 21 doi: 10.1007/s00432-022-04481-5. PMID: 36414814
Contemporary Management of Primary Distal Urethral Cancer.
Traboulsi SL, Witjes JA, Kassouf W
Urol Clin North Am 2016 Nov;43(4):493-503. doi: 10.1016/j.ucl.2016.06.010. PMID: 27717435

Recent clinical studies

Etiology

State of the art and future challenges of urethra-sparing stereotactic body radiotherapy for prostate cancer: a systematic review of literature.
Le Guevelou J, Bosetti DG, Castronovo F, Angrisani A, de Crevoisier R, Zilli T
World J Urol 2023 Nov;41(11):3287-3299. Epub 2023 Sep 5 doi: 10.1007/s00345-023-04579-6. PMID: 37668718Free PMC Article
Posterior urethral polyp in children.
Aballa N, Saiad MO
Afr J Paediatr Surg 2021 Jul-Sep;18(3):148-149. doi: 10.4103/ajps.AJPS_88_20. PMID: 34341198Free PMC Article
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article

Diagnosis

Management of Urethral Hemangioma.
Alam R, Rostom M, Cohen AJ
Urology 2022 Feb;160:227. Epub 2021 Nov 13 doi: 10.1016/j.urology.2021.10.027. PMID: 34780843
Urethral Masses.
Serrell EC, McAchran SE
Obstet Gynecol Clin North Am 2021 Sep;48(3):599-616. doi: 10.1016/j.ogc.2021.05.011. PMID: 34416940
Novel Noninvasive Diagnostics.
Wiley C, Wise CF, Breen M
Vet Clin North Am Small Anim Pract 2019 Sep;49(5):781-791. Epub 2019 Jul 4 doi: 10.1016/j.cvsm.2019.05.002. PMID: 31280902
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Urethral cancer.
Grivas PD, Davenport M, Montie JE, Kunju LP, Feng F, Weizer AZ
Hematol Oncol Clin North Am 2012 Dec;26(6):1291-314. doi: 10.1016/j.hoc.2012.08.006. PMID: 23116581

Therapy

Granular cell tumors of the urethra.
Evmorfopoulos K, Tzortzis V, Vlachostergios PJ
Cancer Treat Res Commun 2023;35:100695. Epub 2023 Mar 17 doi: 10.1016/j.ctarc.2023.100695. PMID: 36940531
Management of Urethral Hemangioma.
Alam R, Rostom M, Cohen AJ
Urology 2022 Feb;160:227. Epub 2021 Nov 13 doi: 10.1016/j.urology.2021.10.027. PMID: 34780843
Effects of perioperative pelvic floor muscle training on early recovery of urinary continence and erectile function in men undergoing radical prostatectomy: a randomized clinical trial.
de Lira GHS, Fornari A, Cardoso LF, Aranchipe M, Kretiska C, Rhoden EL
Int Braz J Urol 2019 Nov-Dec;45(6):1196-1203. doi: 10.1590/S1677-5538.IBJU.2019.0238. PMID: 31808408Free PMC Article
Brachytherapy-related dysuria.
Merrick GS, Butler WM, Wallner KE, Allen Z, Galbreath RW, Lief JH
BJU Int 2005 Mar;95(4):597-602. doi: 10.1111/j.1464-410X.2005.05346.x. PMID: 15705087
Carcinoma in situ.
Lamm DL
Urol Clin North Am 1992 Aug;19(3):499-508. PMID: 1636234

Prognosis

Mucinous and secondary tumors of the prostate.
Osunkoya AO
Mod Pathol 2018 Jan;31(S1):S80-S95. doi: 10.1038/modpathol.2017.132. PMID: 29297488
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Clinicopathological features of carcinoma of the distal penile urethra.
Corbishley CM, Rajab RM, Watkin NA
Semin Diagn Pathol 2015 May;32(3):238-44. Epub 2014 Dec 25 doi: 10.1053/j.semdp.2014.12.015. PMID: 25656527
Melanoma of the glans penis and urethra.
Papeš D, Altarac S, Arslani N, Rajković Z, Antabak A, Ćaćić M
Urology 2014 Jan;83(1):6-11. Epub 2013 Aug 23 doi: 10.1016/j.urology.2013.07.009. PMID: 23978371
Carcinoma in situ.
Lamm DL
Urol Clin North Am 1992 Aug;19(3):499-508. PMID: 1636234

Clinical prediction guides

Clinical features and oncological outcomes of primary female urethral cancer.
Lee W, Yu J, Lee JL, Kim YS, Hong B
J Surg Oncol 2022 Apr;125(5):907-915. Epub 2022 Jan 20 doi: 10.1002/jso.26790. PMID: 35050502
Urethral Masses.
Serrell EC, McAchran SE
Obstet Gynecol Clin North Am 2021 Sep;48(3):599-616. doi: 10.1016/j.ogc.2021.05.011. PMID: 34416940
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Brachytherapy-related dysuria.
Merrick GS, Butler WM, Wallner KE, Allen Z, Galbreath RW, Lief JH
BJU Int 2005 Mar;95(4):597-602. doi: 10.1111/j.1464-410X.2005.05346.x. PMID: 15705087
MR imaging of the male and female urethra.
Ryu J, Kim B
Radiographics 2001 Sep-Oct;21(5):1169-85. doi: 10.1148/radiographics.21.5.g01se121169. PMID: 11553824

Recent systematic reviews

Progress in the treatment of urethral adenocarcinoma.
Guo J, Liang X, Zheng Y, Ma J
J Cancer Res Clin Oncol 2023 Jun;149(6):2693-2698. Epub 2022 Nov 21 doi: 10.1007/s00432-022-04481-5. PMID: 36414814
A systematic review and meta-analysis on complications of transanal total mesorectal excision.
An Y, Roodbeen SX, Talboom K, Tanis PJ, Bemelman WA, Hompes R
Colorectal Dis 2021 Oct;23(10):2527-2538. Epub 2021 Jul 11 doi: 10.1111/codi.15792. PMID: 34174138
Prostate cancer radiation and urethral strictures: a systematic review and meta-analysis.
Awad MA, Gaither TW, Osterberg EC, Murphy GP, Baradaran N, Breyer BN
Prostate Cancer Prostatic Dis 2018 Jun;21(2):168-174. Epub 2018 Jan 2 doi: 10.1038/s41391-017-0028-3. PMID: 29296018
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article
Determining the noninfectious complications of indwelling urethral catheters: a systematic review and meta-analysis.
Hollingsworth JM, Rogers MA, Krein SL, Hickner A, Kuhn L, Cheng A, Chang R, Saint S
Ann Intern Med 2013 Sep 17;159(6):401-10. doi: 10.7326/0003-4819-159-6-201309170-00006. PMID: 24042368

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