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Neoplasm of the urethra

MedGen UID:
12014
•Concept ID:
C0041971
•
Neoplastic Process
Synonym: Urethra neoplasm
SNOMED CT: Neoplasm of urethra (126883004); Tumor of urethra (126883004); Urethral tumor (126883004)
 
HPO: HP:0100517
Monarch Initiative: MONDO:0021239

Definition

The presence of a neoplasm of the urethra. [from HPO]

Professional guidelines

PubMed

Evaluation and management of urethral and periurethral masses in women.
Zuo SW, Napoe GS
Curr Opin Obstet Gynecol 2023 Dec 1;35(6):517-524. Epub 2023 Aug 29 doi: 10.1097/GCO.0000000000000914. PMID: 37678190
Infiltrating bladder cancer: prognostic factors, follow-up and treatment of relapses.
Hernández-Fernández C, Herranz-Amo F, Moralejo-Gárate M, Subirá-Ríos D, Caño-Velasco J, Barbas-Bernardos G
Actas Urol Esp 2017 Jul-Aug;41(6):352-358. Epub 2016 Aug 22 doi: 10.1016/j.acuro.2016.07.006. PMID: 27561847
Diagnosis and management of urothelial carcinoma of the bladder.
Tanaka MF, Sonpavde G
Postgrad Med 2011 May;123(3):43-55. doi: 10.3810/pgm.2011.05.2283. PMID: 21566415

Recent clinical studies

Etiology

Radiotherapy in Metastatic Urothelial Carcinoma: Rationale and Clinical Applications.
Vassiliou V, Katsila T, Sodergren SC, Kardamakis D
Anticancer Res 2022 Aug;42(8):3767-3778. doi: 10.21873/anticanres.15867. PMID: 35896266
Orthotopic neobladder after cystectomy for bladder cancer.
Kakizoe T
Proc Jpn Acad Ser B Phys Biol Sci 2020;96(7):255-265. doi: 10.2183/pjab.96.019. PMID: 32788549Free PMC Article
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article

Diagnosis

Urethral Masses.
Serrell EC, McAchran SE
Obstet Gynecol Clin North Am 2021 Sep;48(3):599-616. doi: 10.1016/j.ogc.2021.05.011. PMID: 34416940
Novel Noninvasive Diagnostics.
Wiley C, Wise CF, Breen M
Vet Clin North Am Small Anim Pract 2019 Sep;49(5):781-791. Epub 2019 Jul 4 doi: 10.1016/j.cvsm.2019.05.002. PMID: 31280902
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Urethral cancer.
Grivas PD, Davenport M, Montie JE, Kunju LP, Feng F, Weizer AZ
Hematol Oncol Clin North Am 2012 Dec;26(6):1291-314. doi: 10.1016/j.hoc.2012.08.006. PMID: 23116581

Therapy

Management of Urethral Hemangioma.
Alam R, Rostom M, Cohen AJ
Urology 2022 Feb;160:227. Epub 2021 Nov 13 doi: 10.1016/j.urology.2021.10.027. PMID: 34780843
Orthotopic neobladder after cystectomy for bladder cancer.
Kakizoe T
Proc Jpn Acad Ser B Phys Biol Sci 2020;96(7):255-265. doi: 10.2183/pjab.96.019. PMID: 32788549Free PMC Article
Effects of perioperative pelvic floor muscle training on early recovery of urinary continence and erectile function in men undergoing radical prostatectomy: a randomized clinical trial.
de Lira GHS, Fornari A, Cardoso LF, Aranchipe M, Kretiska C, Rhoden EL
Int Braz J Urol 2019 Nov-Dec;45(6):1196-1203. doi: 10.1590/S1677-5538.IBJU.2019.0238. PMID: 31808408Free PMC Article
Brachytherapy-related dysuria.
Merrick GS, Butler WM, Wallner KE, Allen Z, Galbreath RW, Lief JH
BJU Int 2005 Mar;95(4):597-602. doi: 10.1111/j.1464-410X.2005.05346.x. PMID: 15705087
Carcinoma in situ.
Lamm DL
Urol Clin North Am 1992 Aug;19(3):499-508. PMID: 1636234

Prognosis

Mucinous and secondary tumors of the prostate.
Osunkoya AO
Mod Pathol 2018 Jan;31(S1):S80-S95. doi: 10.1038/modpathol.2017.132. PMID: 29297488
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article
Clear cell adenocarcinoma of the urethra: review of the literature.
Venyo AK
Int J Surg Oncol 2015;2015:790235. Epub 2015 Jan 20 doi: 10.1155/2015/790235. PMID: 25685552Free PMC Article
Obstructive uropathy.
Tseng TY, Stoller ML
Clin Geriatr Med 2009 Aug;25(3):437-43. doi: 10.1016/j.cger.2009.06.003. PMID: 19765491

Clinical prediction guides

Urethral Masses.
Serrell EC, McAchran SE
Obstet Gynecol Clin North Am 2021 Sep;48(3):599-616. doi: 10.1016/j.ogc.2021.05.011. PMID: 34416940
Carcinoma of the urethra.
Zhang M, Adeniran AJ, Vikram R, Tamboli P, Pettaway C, Bondaruk J, Liu J, Baggerly K, Czerniak B
Hum Pathol 2018 Feb;72:35-44. Epub 2017 Aug 18 doi: 10.1016/j.humpath.2017.08.006. PMID: 28827100Free PMC Article
Primary malignant melanoma of the urethra: a systematic analysis of the current literature.
El-Safadi S, Estel R, Mayser P, Muenstedt K
Arch Gynecol Obstet 2014 May;289(5):935-43. Epub 2013 Dec 27 doi: 10.1007/s00404-013-3130-3. PMID: 24370958
Brachytherapy-related dysuria.
Merrick GS, Butler WM, Wallner KE, Allen Z, Galbreath RW, Lief JH
BJU Int 2005 Mar;95(4):597-602. doi: 10.1111/j.1464-410X.2005.05346.x. PMID: 15705087
MR imaging of the male and female urethra.
Ryu J, Kim B
Radiographics 2001 Sep-Oct;21(5):1169-85. doi: 10.1148/radiographics.21.5.g01se121169. PMID: 11553824

Recent systematic reviews

Comparison of various types of lasers and transurethral resection in the treatment of bladder tumors: a systematic review and meta-analysis.
Allameh F, Sangian A, Razaghi M, Razzaghi Z, Alahyari S, Amini A
Lasers Med Sci 2022 Feb;37(1):95-101. Epub 2022 Jan 13 doi: 10.1007/s10103-021-03479-8. PMID: 35022872
A systematic review and meta-analysis on complications of transanal total mesorectal excision.
An Y, Roodbeen SX, Talboom K, Tanis PJ, Bemelman WA, Hompes R
Colorectal Dis 2021 Oct;23(10):2527-2538. Epub 2021 Jul 11 doi: 10.1111/codi.15792. PMID: 34174138
Prostate cancer radiation and urethral strictures: a systematic review and meta-analysis.
Awad MA, Gaither TW, Osterberg EC, Murphy GP, Baradaran N, Breyer BN
Prostate Cancer Prostatic Dis 2018 Jun;21(2):168-174. Epub 2018 Jan 2 doi: 10.1038/s41391-017-0028-3. PMID: 29296018
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article
Determining the noninfectious complications of indwelling urethral catheters: a systematic review and meta-analysis.
Hollingsworth JM, Rogers MA, Krein SL, Hickner A, Kuhn L, Cheng A, Chang R, Saint S
Ann Intern Med 2013 Sep 17;159(6):401-10. doi: 10.7326/0003-4819-159-6-201309170-00006. PMID: 24042368

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