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Ampulla of Vater carcinoma

MedGen UID:
120461
Concept ID:
C0262401
Neoplastic Process
Synonyms: AMPCA; Ampulla of Vater Cancer; ampulla of Vater cancer; Ampulla of Vater Carcinoma; ampulla of Vater carcinoma; ampullary cancer; Ampullary carcinoma; Ampullary Carcinoma; ampullary carcinoma; Ampulloma; Carcinoma of ampulla of Vater; carcinoma of ampulla of vater; carcinoma of hepatopancreatic ampulla; carcinoma of the ampulla of vater; Carcinoma of the ampulla of Vater; hepatopancreatic ampulla carcinoma
SNOMED CT: Carcinoma of ampulla of Vater (254609000); Ampullary carcinoma (254609000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
HPO: HP:0031524
Monarch Initiative: MONDO:0017590
Orphanet: ORPHA300557

Definition

A carcinoma originating in the ampulla of Vater (also known as the hepatopancreatic duct), which is formed by the union of the pancreatic duct and the common bile duct. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpulla of Vater carcinoma
Follow this link to review classifications for Ampulla of Vater carcinoma in Orphanet.

Professional guidelines

PubMed

Zanuso V, Nash T, Casolino R, Armstrong G, Pallise O, Milne J, Braconi C
BMC Cancer 2024 May 16;24(1):597. doi: 10.1186/s12885-024-12279-6. PMID: 38755562
Aiura K, Hibi T, Fujisaki H, Kitago M, Tanabe M, Kawachi S, Itano O, Shinoda M, Yagi H, Masugi Y, Sakamoto M, Kitagawa Y
J Hepatobiliary Pancreat Sci 2012 Nov;19(6):707-16. doi: 10.1007/s00534-011-0492-4. PMID: 22203456Free PMC Article

Recent clinical studies

Etiology

Shimizu Y, Ashida R, Sugiura T, Okamura Y, Ito T, Yamamoto Y, Ohgi K, Otsuka S, Notsu A, Uesaka K
World J Surg 2022 Jan;46(1):246-258. Epub 2021 Oct 18 doi: 10.1007/s00268-021-06346-3. PMID: 34661701
Komine R, Kojima M, Ishi G, Kudo M, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Kobayashi T, Akimoto T, Murakami A, Sasaki M, Tanaka M, Matsuzaki A, Ohike N, Uchida K, Sugiyama T, Hirabayashi K, Tajiri T, Ishida K, Kai K, Omori Y, Notohara K, Yamaguchi H, Matsuda Y, Naito Y, Fukumura Y, Hamada Y, Mihara Y, Masugi Y, Gotohda N, Harada K, Fukushima N, Furukawa T
Cancer Med 2021 Jun;10(11):3499-3510. Epub 2021 May 19 doi: 10.1002/cam4.3809. PMID: 34008914Free PMC Article
Kim JH, Jeong JH, Ryoo BY, Kim KP, Chang HM, Oh D, Song TJ, Lee SS, Seo DW, Lee SK, Kim MH, Park Y, Kwon JW, Hwang DW, Lee JH, Lee W, Kim SC, Yoo C, Song KB
Cancer Res Treat 2021 Apr;53(2):424-435. Epub 2020 Nov 9 doi: 10.4143/crt.2020.953. PMID: 33171024Free PMC Article
Matsui S, Yamamoto Y, Sugiura T, Okamura Y, Ito T, Ashida R, Ohgi K, Imamura T, Uesaka K
World J Surg 2021 Jan;45(1):270-278. Epub 2020 Sep 9 doi: 10.1007/s00268-020-05770-1. PMID: 32909124
Giuliani J, Piacentini P, Bonetti A
Tumori 2015 Jun 25;101(3):e75-8. doi: 10.5301/tj.5000267. PMID: 25908045

Diagnosis

Matsui S, Yamamoto Y, Okamura Y, Ito T, Ashida R, Ohgi K, Yamada M, Otsuka S, Uesaka K, Sugiura T
Anticancer Res 2022 Jun;42(6):3169-3176. doi: 10.21873/anticanres.15806. PMID: 35641260
Usenko A, Vasiliev O, Tsubera B
Georgian Med News 2021 Jul-Aug;(316-317):16-21. PMID: 34511437
Komine R, Kojima M, Ishi G, Kudo M, Sugimoto M, Kobayashi S, Takahashi S, Konishi M, Kobayashi T, Akimoto T, Murakami A, Sasaki M, Tanaka M, Matsuzaki A, Ohike N, Uchida K, Sugiyama T, Hirabayashi K, Tajiri T, Ishida K, Kai K, Omori Y, Notohara K, Yamaguchi H, Matsuda Y, Naito Y, Fukumura Y, Hamada Y, Mihara Y, Masugi Y, Gotohda N, Harada K, Fukushima N, Furukawa T
Cancer Med 2021 Jun;10(11):3499-3510. Epub 2021 May 19 doi: 10.1002/cam4.3809. PMID: 34008914Free PMC Article
Jayaramayya K, Balachandar V, Santhy KS
Mutat Res Rev Mutat Res 2018 Apr-Jun;776:10-22. Epub 2018 Mar 17 doi: 10.1016/j.mrrev.2018.03.002. PMID: 29807574
Giuliani J, Piacentini P, Bonetti A
Tumori 2015 Jun 25;101(3):e75-8. doi: 10.5301/tj.5000267. PMID: 25908045

Therapy

Uijterwijk BA, Kasai M, Lemmers DHL, Chinnusamy P, van Hilst J, Ielpo B, Wei K, Song KB, Kim SC, Klompmaker S, Jang JY, Herremans KM, Bencini L, Coratti A, Mazzola M, Menon KV, Goh BKP, Qin R, Besselink MG, Abu Hilal M; International Study Group on non-pancreatic periAmpullary CAncer (ISGACA)
Langenbecks Arch Surg 2023 Aug 15;408(1):311. doi: 10.1007/s00423-023-03047-4. PMID: 37581763Free PMC Article
Okano K, Suzuki Y
World J Gastroenterol 2019 Dec 21;25(47):6847-6856. doi: 10.3748/wjg.v25.i47.6847. PMID: 31885425Free PMC Article
Giuliani J, Piacentini P, Bonetti A
Tumori 2015 Jun 25;101(3):e75-8. doi: 10.5301/tj.5000267. PMID: 25908045
Kobrinsky B, Joseph SO, Muggia F, Liebes L, Beric A, Malankar A, Ivy P, Hochster H
Cancer Chemother Pharmacol 2013 Nov;72(5):1073-8. Epub 2013 Sep 19 doi: 10.1007/s00280-013-2295-6. PMID: 24048674
Falconi M, Crippa S, Domínguez I, Barugola G, Capelli P, Marcucci S, Beghelli S, Scarpa A, Bassi C, Pederzoli P
Ann Surg Oncol 2008 Nov;15(11):3178-86. Epub 2008 Aug 20 doi: 10.1245/s10434-008-0099-4. PMID: 18712568

Prognosis

Matsui S, Yamamoto Y, Okamura Y, Ito T, Ashida R, Ohgi K, Yamada M, Otsuka S, Uesaka K, Sugiura T
Anticancer Res 2022 Jun;42(6):3169-3176. doi: 10.21873/anticanres.15806. PMID: 35641260
Kim JH, Jeong JH, Ryoo BY, Kim KP, Chang HM, Oh D, Song TJ, Lee SS, Seo DW, Lee SK, Kim MH, Park Y, Kwon JW, Hwang DW, Lee JH, Lee W, Kim SC, Yoo C, Song KB
Cancer Res Treat 2021 Apr;53(2):424-435. Epub 2020 Nov 9 doi: 10.4143/crt.2020.953. PMID: 33171024Free PMC Article
Seo HK, Hwang DW, Lee JH, Song KB, Shin SH, Kwon J, Lee YJ, Kim SC
Surg Oncol 2019 Jun;29:33-40. Epub 2019 Feb 15 doi: 10.1016/j.suronc.2019.02.006. PMID: 31196491
Jayaramayya K, Balachandar V, Santhy KS
Mutat Res Rev Mutat Res 2018 Apr-Jun;776:10-22. Epub 2018 Mar 17 doi: 10.1016/j.mrrev.2018.03.002. PMID: 29807574
Giuliani J, Piacentini P, Bonetti A
Tumori 2015 Jun 25;101(3):e75-8. doi: 10.5301/tj.5000267. PMID: 25908045

Clinical prediction guides

Shimizu Y, Ashida R, Sugiura T, Okamura Y, Ito T, Yamamoto Y, Ohgi K, Otsuka S, Notsu A, Uesaka K
World J Surg 2022 Jan;46(1):246-258. Epub 2021 Oct 18 doi: 10.1007/s00268-021-06346-3. PMID: 34661701
Usenko A, Vasiliev O, Tsubera B
Georgian Med News 2021 Jul-Aug;(316-317):16-21. PMID: 34511437
Kim JH, Jeong JH, Ryoo BY, Kim KP, Chang HM, Oh D, Song TJ, Lee SS, Seo DW, Lee SK, Kim MH, Park Y, Kwon JW, Hwang DW, Lee JH, Lee W, Kim SC, Yoo C, Song KB
Cancer Res Treat 2021 Apr;53(2):424-435. Epub 2020 Nov 9 doi: 10.4143/crt.2020.953. PMID: 33171024Free PMC Article
Seo HK, Hwang DW, Lee JH, Song KB, Shin SH, Kwon J, Lee YJ, Kim SC
Surg Oncol 2019 Jun;29:33-40. Epub 2019 Feb 15 doi: 10.1016/j.suronc.2019.02.006. PMID: 31196491
Giuliani J, Piacentini P, Bonetti A
Tumori 2015 Jun 25;101(3):e75-8. doi: 10.5301/tj.5000267. PMID: 25908045

Recent systematic reviews

Uijterwijk BA, Kasai M, Lemmers DHL, Chinnusamy P, van Hilst J, Ielpo B, Wei K, Song KB, Kim SC, Klompmaker S, Jang JY, Herremans KM, Bencini L, Coratti A, Mazzola M, Menon KV, Goh BKP, Qin R, Besselink MG, Abu Hilal M; International Study Group on non-pancreatic periAmpullary CAncer (ISGACA)
Langenbecks Arch Surg 2023 Aug 15;408(1):311. doi: 10.1007/s00423-023-03047-4. PMID: 37581763Free PMC Article
Luchini C, Veronese N, Nottegar A, Riva G, Pilati C, Mafficini A, Stubbs B, Simbolo M, Mombello A, Corbo V, Cheng L, Yachida S, Wood LD, Lawlor RT, Salvia R, Scarpa A
Pancreas 2019 Jan;48(1):70-76. doi: 10.1097/MPA.0000000000001194. PMID: 30451797

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