From HPO
Squamous cell carcinoma- MedGen UID:
- 2874
- •Concept ID:
- C0007137
- •
- Neoplastic Process
The presence of squamous cell carcinoma of the skin.
Knee flexion contracture- MedGen UID:
- 98042
- •Concept ID:
- C0409355
- •
- Finding
A bent (flexed) knee joint that cannot be straightened actively or passively.
Pes cavus- MedGen UID:
- 675590
- •Concept ID:
- C0728829
- •
- Congenital Abnormality
The presence of an unusually high plantar arch. Also called high instep, pes cavus refers to a distinctly hollow form of the sole of the foot when it is bearing weight.
Sensorineural hearing impairment- MedGen UID:
- 9164
- •Concept ID:
- C0018784
- •
- Disease or Syndrome
A type of hearing impairment in one or both ears related to an abnormal functionality of the cochlear nerve.
Photophobia- MedGen UID:
- 43220
- •Concept ID:
- C0085636
- •
- Sign or Symptom
Excessive sensitivity to light with the sensation of discomfort or pain in the eyes due to exposure to bright light.
Corneal scarring- MedGen UID:
- 83899
- •Concept ID:
- C0349702
- •
- Finding
Replacement of corneal tissue with scar tissue as a result of injury to the deeper layers of the cornea.
Elbow flexion contracture- MedGen UID:
- 98367
- •Concept ID:
- C0409338
- •
- Acquired Abnormality
An elbow contracture that limits the ability of the elbow joint to be extended (straightened), meaning that the elbow is fixed in an flexed (bent) position.
Keratitis- MedGen UID:
- 44013
- •Concept ID:
- C0022568
- •
- Disease or Syndrome
Inflammation of the cornea.
Keratoconjunctivitis sicca- MedGen UID:
- 9620
- •Concept ID:
- C0022575
- •
- Disease or Syndrome
Dryness of the eye related to deficiency of the tear film components (aqueous, mucin, or lipid), lid surface abnormalities, or epithelial abnormalities. Keratoconjunctivitis sicca often results in a scratchy or sandy sensation (foreign body sensation) in the eyes, and may also be associated with itching, inability to produce tears, photosensitivity, redness, pain, and difficulty in moving the eyelids.
Recurrent bacterial skin infections- MedGen UID:
- 322727
- •Concept ID:
- C1835686
- •
- Finding
Increased susceptibility to bacterial infections of the skin, as manifested by recurrent episodes of infectious dermatitis.
Oral mucosa leukoplakia- MedGen UID:
- 9738
- •Concept ID:
- C0023532
- •
- Neoplastic Process
A thickened white patch on the oral mucosa that cannot be rubbed off.
Furrowed tongue- MedGen UID:
- 21583
- •Concept ID:
- C0040412
- •
- Disease or Syndrome
Accentuation of the grooves on the dorsal surface of the tongue.
Microdontia- MedGen UID:
- 66008
- •Concept ID:
- C0240340
- •
- Congenital Abnormality
Decreased size of the teeth, which can be defined as a mesiodistal tooth diameter (width) more than 2 SD below mean. Alternatively, an apparently decreased maximum width of tooth.
Sparse eyebrow- MedGen UID:
- 371332
- •Concept ID:
- C1832446
- •
- Finding
Decreased density/number of eyebrow hairs.
Hypohidrosis- MedGen UID:
- 43796
- •Concept ID:
- C0020620
- •
- Disease or Syndrome
Abnormally diminished capacity to sweat.
Ichthyosis- MedGen UID:
- 7002
- •Concept ID:
- C0020757
- •
- Disease or Syndrome
An abnormality of the skin characterized the presence of excessive amounts of dry surface scales on the skin resulting from an abnormality of keratinization.
Trichiasis- MedGen UID:
- 66367
- •Concept ID:
- C0221259
- •
- Disease or Syndrome
Inversion and rubbing of the eyelashes against the globe of the eye.
Nail dystrophy- MedGen UID:
- 66368
- •Concept ID:
- C0221260
- •
- Disease or Syndrome
Onychodystrophy (nail dystrophy) refers to nail changes apart from changes of the color (nail dyschromia) and involves partial or complete disruption of the various keratinous layers of the nail plate.
Hyperkeratosis- MedGen UID:
- 209030
- •Concept ID:
- C0870082
- •
- Disease or Syndrome
Hyperkeratosis is thickening of the outer layer of the skin, the stratum corneum, which is composed of large, polyhedral, plate-like envelopes filled with keratin which are the dead cells that have migrated up from the stratum granulosum.
Nail dysplasia- MedGen UID:
- 331737
- •Concept ID:
- C1834405
- •
- Congenital Abnormality
The presence of developmental dysplasia of the nail.
Sparse eyelashes- MedGen UID:
- 375151
- •Concept ID:
- C1843300
- •
- Finding
Decreased density/number of eyelashes.
Absent pubic hair- MedGen UID:
- 349155
- •Concept ID:
- C1859391
- •
- Finding
Absence of pubic hair.
Absent axillary hair- MedGen UID:
- 347869
- •Concept ID:
- C1859392
- •
- Finding
Absence of axillary hair.
Corneal ulceration- MedGen UID:
- 40486
- •Concept ID:
- C0010043
- •
- Disease or Syndrome
Disruption of the epithelial layer of the cornea with involvement of the underlying stroma.
Recurrent corneal erosions- MedGen UID:
- 56353
- •Concept ID:
- C0155119
- •
- Disease or Syndrome
The presence of recurrent corneal epithelial erosions. Although most corneal epithelial defects heal quickly, some may show recurrent ulcerations.
Blindness- MedGen UID:
- 99138
- •Concept ID:
- C0456909
- •
- Disease or Syndrome
Blindness is the condition of lacking visual perception defined as visual perception below 3/60 and/or a visual field of no greater than 10 degrees in radius around central fixation.
- Abnormality of head or neck
- Abnormality of limbs
- Abnormality of the ear
- Abnormality of the eye
- Abnormality of the immune system
- Abnormality of the integument
- Abnormality of the musculoskeletal system
- Abnormality of the nervous system
- Neoplasm