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Glomerular disorder

MedGen UID:
1241729
•Concept ID:
CN580795
•
Disease or Syndrome
Synonyms: Glomerular disease; Glomerulopathies
 
Monarch Initiative: MONDO:0019722
Orphanet: ORPHA93548

Definition

A disease involving the renal glomerulus. [from MONDO]

Professional guidelines

PubMed

Pathophysiology and treatment of focal segmental glomerulosclerosis: the role of animal models.
de Mik SM, Hoogduijn MJ, de Bruin RW, Dor FJ
BMC Nephrol 2013 Apr 1;14:74. doi: 10.1186/1471-2369-14-74. PMID: 23547922Free PMC Article
Predicting the response to growth hormone treatment in short children with chronic kidney disease.
Mehls O, Lindberg A, Nissel R, Haffner D, Hokken-Koelega A, Ranke MB
J Clin Endocrinol Metab 2010 Feb;95(2):686-92. Epub 2009 Dec 11 doi: 10.1210/jc.2009-1114. PMID: 20008024
Treatment of steroid sensitive nephrotic syndrome.
Abeyagunawardena AS
Indian J Pediatr 2005 Sep;72(9):763-9. doi: 10.1007/BF02734149. PMID: 16186679

Recent clinical studies

Etiology

Thin Basement Membrane: An Underrated Cause of End-Stage Renal Disease.
Uzzo M, Moroni G, Ponticelli C
Nephron 2023;147(7):383-391. Epub 2023 Mar 7 doi: 10.1159/000528243. PMID: 36882005
Urinary metabolic abnormalities in children with idiopathic hematuria.
Valavi E, Nickavar A, Aeene A
J Pediatr Urol 2019 Apr;15(2):165.e1-165.e4. Epub 2018 Nov 10 doi: 10.1016/j.jpurol.2018.11.003. PMID: 30528095
Recurrence of Focal and Segmental Glomerulosclerosis After Transplantation.
Canaud G, Delville M, Legendre C
Transplantation 2016 Feb;100(2):284-7. doi: 10.1097/TP.0000000000000902. PMID: 26247557
New players in the pathogenesis of focal segmental glomerulosclerosis.
Schell C, Huber TB
Nephrol Dial Transplant 2012 Sep;27(9):3406-12. Epub 2012 Jul 5 doi: 10.1093/ndt/gfs273. PMID: 22767631
Proteinuria: potential causes and approach to evaluation.
Wingo CS, Clapp WL
Am J Med Sci 2000 Sep;320(3):188-94. doi: 10.1097/00000441-200009000-00010. PMID: 11014373

Diagnosis

Primary IgA Nephropathy: New Insights and Emerging Therapies.
Selvaskandan H, Jhaveri KD, Rizk DV
Adv Kidney Dis Health 2024 May;31(3):180-193. doi: 10.1053/j.akdh.2024.04.002. PMID: 39004458
Thin Basement Membrane: An Underrated Cause of End-Stage Renal Disease.
Uzzo M, Moroni G, Ponticelli C
Nephron 2023;147(7):383-391. Epub 2023 Mar 7 doi: 10.1159/000528243. PMID: 36882005
Recurrence of Focal and Segmental Glomerulosclerosis After Transplantation.
Canaud G, Delville M, Legendre C
Transplantation 2016 Feb;100(2):284-7. doi: 10.1097/TP.0000000000000902. PMID: 26247557
Pathology of thin basement membrane nephropathy.
Foster K, Markowitz GS, D'Agati VD
Semin Nephrol 2005 May;25(3):149-58. doi: 10.1016/j.semnephrol.2005.01.006. PMID: 15880325
Proteinuria: potential causes and approach to evaluation.
Wingo CS, Clapp WL
Am J Med Sci 2000 Sep;320(3):188-94. doi: 10.1097/00000441-200009000-00010. PMID: 11014373

Therapy

Asparagine endopeptidase protects podocytes in adriamycin-induced nephropathy by regulating actin dynamics through cleaving transgelin.
Qiu Y, Lei C, Zeng J, Xie Y, Cao Y, Yuan Q, Su H, Zhang Z, Zhang C
Mol Ther 2023 Nov 1;31(11):3337-3354. Epub 2023 Sep 9 doi: 10.1016/j.ymthe.2023.09.003. PMID: 37689970Free PMC Article
Quality of life in children with nephrotic syndrome: a cross-sectional study using Hindi version of PedsQL 4.0 Generic Core Scales.
Mazahir R, Anand K, Pruthi PK
Clin Exp Nephrol 2022 Jun;26(6):552-560. Epub 2022 Feb 1 doi: 10.1007/s10157-022-02186-0. PMID: 35106675
Pembrolizumab-induced focal segmental glomerulosclerosis: A case report.
Kim DW, Jeon H, Kim S, Lee W, Kim HJ, Rhee H, Song SH, Seong EY
Medicine (Baltimore) 2021 Oct 29;100(43):e27546. doi: 10.1097/MD.0000000000027546. PMID: 34713828Free PMC Article
Recurrence of Focal and Segmental Glomerulosclerosis After Transplantation.
Canaud G, Delville M, Legendre C
Transplantation 2016 Feb;100(2):284-7. doi: 10.1097/TP.0000000000000902. PMID: 26247557
Proteinuria: potential causes and approach to evaluation.
Wingo CS, Clapp WL
Am J Med Sci 2000 Sep;320(3):188-94. doi: 10.1097/00000441-200009000-00010. PMID: 11014373

Prognosis

Primary IgA Nephropathy: New Insights and Emerging Therapies.
Selvaskandan H, Jhaveri KD, Rizk DV
Adv Kidney Dis Health 2024 May;31(3):180-193. doi: 10.1053/j.akdh.2024.04.002. PMID: 39004458
Thin Basement Membrane: An Underrated Cause of End-Stage Renal Disease.
Uzzo M, Moroni G, Ponticelli C
Nephron 2023;147(7):383-391. Epub 2023 Mar 7 doi: 10.1159/000528243. PMID: 36882005
Leptin and chronic kidney diseases.
Mao S, Fang L, Liu F, Jiang S, Wu L, Zhang J
J Recept Signal Transduct Res 2018 Apr;38(2):89-94. Epub 2018 Feb 1 doi: 10.1080/10799893.2018.1431278. PMID: 29388492
New players in the pathogenesis of focal segmental glomerulosclerosis.
Schell C, Huber TB
Nephrol Dial Transplant 2012 Sep;27(9):3406-12. Epub 2012 Jul 5 doi: 10.1093/ndt/gfs273. PMID: 22767631
Pathology of thin basement membrane nephropathy.
Foster K, Markowitz GS, D'Agati VD
Semin Nephrol 2005 May;25(3):149-58. doi: 10.1016/j.semnephrol.2005.01.006. PMID: 15880325

Clinical prediction guides

A Case Report of Fibrillary Glomerulonephritis with Mild Albuminuria: A Viewpoint on Proteomics.
Guerra-Torres XE
Saudi J Kidney Dis Transpl 2023 Sep 1;34(5):458-461. Epub 2024 Mar 11 doi: 10.4103/1319-2442.397209. PMID: 38995306
Quality of life in children with nephrotic syndrome: a cross-sectional study using Hindi version of PedsQL 4.0 Generic Core Scales.
Mazahir R, Anand K, Pruthi PK
Clin Exp Nephrol 2022 Jun;26(6):552-560. Epub 2022 Feb 1 doi: 10.1007/s10157-022-02186-0. PMID: 35106675
Leptin and chronic kidney diseases.
Mao S, Fang L, Liu F, Jiang S, Wu L, Zhang J
J Recept Signal Transduct Res 2018 Apr;38(2):89-94. Epub 2018 Feb 1 doi: 10.1080/10799893.2018.1431278. PMID: 29388492
A kidney-specific genome-scale metabolic network model for analyzing focal segmental glomerulosclerosis.
Sohrabi-Jahromi S, Marashi SA, Kalantari S
Mamm Genome 2016 Apr;27(3-4):158-67. Epub 2016 Feb 29 doi: 10.1007/s00335-016-9622-2. PMID: 26923795
Proteinuria: potential causes and approach to evaluation.
Wingo CS, Clapp WL
Am J Med Sci 2000 Sep;320(3):188-94. doi: 10.1097/00000441-200009000-00010. PMID: 11014373

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