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Vulvar vestibulitis

MedGen UID:
124347
Concept ID:
C0269084
Disease or Syndrome
Synonyms: Vestibulitides, Vulvar; Vestibulitis, Vulvar; Vulvar Vestibulitides; Vulvar Vestibulitis; Vulvar Vestibulitis Syndrome
SNOMED CT: Vulval vestibulitis (30833006); Vestibulodynia (30833006); Vulvar vestibulitis (30833006)

Definition

Inflammation of the vulvar vestibular region at the entrance of the VAGINA, generally involving surface mucosa and submucosal vestibular glands. It is characterized by ERYTHEMA and chronic recurrent pain in this area. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar vestibulitis

Professional guidelines

PubMed

Heim LJ
Am Fam Physician 2001 Apr 15;63(8):1535-44. PMID: 11327429
Rogstad KE
Int J STD AIDS 2000 Sep;11(9):557-62. doi: 10.1258/0956462001916443. PMID: 10997495
Paavonen J
Ann Med 1995 Apr;27(2):175-81. doi: 10.3109/07853899509031955. PMID: 7632410

Recent clinical studies

Etiology

Champaneria R, D'Andrea RM, Latthe PM
Int Urogynecol J 2016 May;27(5):709-22. Epub 2015 Sep 25 doi: 10.1007/s00192-015-2833-3. PMID: 26407563
Smart OC, MacLean AB
Curr Opin Obstet Gynecol 2003 Dec;15(6):497-500. doi: 10.1097/00001703-200312000-00007. PMID: 14624216
Edwards L
Am J Obstet Gynecol 2003 Sep;189(3 Suppl):S24-30. doi: 10.1067/s0002-9378(03)00790-7. PMID: 14532900
Metts JF
Am Fam Physician 1999 Mar 15;59(6):1547-56, 1561-2. PMID: 10193596
Paavonen J
Ann Med 1995 Apr;27(2):175-81. doi: 10.3109/07853899509031955. PMID: 7632410

Diagnosis

Ben-Aroya Z, Edwards L
Semin Cutan Med Surg 2015 Dec;34(4):192-8. doi: 10.12788/j.sder.2015.0181. PMID: 26650698
Stein SL
Gastroenterol Clin North Am 2013 Dec;42(4):785-800. Epub 2013 Oct 23 doi: 10.1016/j.gtc.2013.08.005. PMID: 24280400
Smart OC, MacLean AB
Curr Opin Obstet Gynecol 2003 Dec;15(6):497-500. doi: 10.1097/00001703-200312000-00007. PMID: 14624216
Driver KA
Nurse Pract 2002 Jul;27(7):24-35; quiz 35-7. doi: 10.1097/00006205-200207000-00005. PMID: 12131798
Marinoff SC, Turner ML
Dermatol Clin 1992 Apr;10(2):435-44. PMID: 1606769

Therapy

Paavonen J, Eschenbach DA
Front Cell Infect Microbiol 2021;11:678961. Epub 2021 Jun 17 doi: 10.3389/fcimb.2021.678961. PMID: 34222047Free PMC Article
Champaneria R, D'Andrea RM, Latthe PM
Int Urogynecol J 2016 May;27(5):709-22. Epub 2015 Sep 25 doi: 10.1007/s00192-015-2833-3. PMID: 26407563
Tommola P, Unkila-Kallio L, Paavonen J
Acta Obstet Gynecol Scand 2010 Nov;89(11):1385-95. doi: 10.3109/00016349.2010.512071. PMID: 20955094
Farage MA, Galask RP
Eur J Obstet Gynecol Reprod Biol 2005 Nov 1;123(1):9-16. Epub 2005 Jun 21 doi: 10.1016/j.ejogrb.2005.05.004. PMID: 15927350
Marinoff SC, Turner ML
Am J Obstet Gynecol 1991 Oct;165(4 Pt 2):1228-33. doi: 10.1016/s0002-9378(12)90732-2. PMID: 1659198

Prognosis

Ben-Aroya Z, Edwards L
Semin Cutan Med Surg 2015 Dec;34(4):192-8. doi: 10.12788/j.sder.2015.0181. PMID: 26650698
Edwards L
Am J Obstet Gynecol 2003 Sep;189(3 Suppl):S24-30. doi: 10.1067/s0002-9378(03)00790-7. PMID: 14532900
Byth JL
Australas J Dermatol 1998 Aug;39(3):139-48; quiz 149-50. doi: 10.1111/j.1440-0960.1998.tb01270.x. PMID: 9737039
Paavonen J
Ann Med 1995 Apr;27(2):175-81. doi: 10.3109/07853899509031955. PMID: 7632410
McKay M
J Reprod Med 1988 Aug;33(8):695-8. PMID: 3050074

Clinical prediction guides

Farage MA, Miller KW, Ledger WJ
Obstet Gynecol Surv 2008 Jul;63(7):445-64. doi: 10.1097/OGX.0b013e318172ee25. PMID: 18559121
Zolnoun DA, Rohl J, Moore CG, Perinetti-Liebert C, Lamvu GM, Maixner W
Clin J Pain 2008 Mar-Apr;24(3):187-91. doi: 10.1097/AJP.0b013e318159f976. PMID: 18287822Free PMC Article
Edgardh K, Abdelnoor M
Acta Derm Venereol 2007;87(4):350-4. doi: 10.2340/00015555-0250. PMID: 17598040
Granot M, Friedman M, Yarnitsky D, Tamir A, Zimmer EZ
Am J Obstet Gynecol 2004 Jul;191(1):138-42. doi: 10.1016/j.ajog.2003.09.060. PMID: 15295354
Wesselmann U
World J Urol 2001 Jun;19(3):180-5. doi: 10.1007/s003450100201. PMID: 11469605

Recent systematic reviews

Sacinti KG, Razeghian H, Awad-Igbaria Y, Lima-Silva J, Palzur E, Vieira-Baptista P, Verstraelen H, Bornstein J
J Low Genit Tract Dis 2024 Jan 1;28(1):64-72. Epub 2023 Nov 13 doi: 10.1097/LGT.0000000000000780. PMID: 37963335
Champaneria R, D'Andrea RM, Latthe PM
Int Urogynecol J 2016 May;27(5):709-22. Epub 2015 Sep 25 doi: 10.1007/s00192-015-2833-3. PMID: 26407563

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