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Iris cyst

MedGen UID:
124385
•Concept ID:
C0271119
•
Disease or Syndrome; Finding
Synonyms: Cyst of iris; Cyst of Iris; Cyst of the Iris; Iris Cyst
SNOMED CT: Iris cyst (37761009); Cyst of iris (37761009)
 
HPO: HP:0011523

Definition

An iris cyst is composed of a single cell layer of epithelium and is filled with fluid. [from HPO]

Conditions with this feature

Iris pigment epithelium anomalies
MedGen UID:
357091
•Concept ID:
C1866608
•
Disease or Syndrome
See: Condition Record
Oculoauricular syndrome
MedGen UID:
393758
•Concept ID:
C2677500
•
Disease or Syndrome
Oculoauricular syndrome (OCACS) is characterized by complex ocular anomalies, including congenital cataract, anterior segment dysgenesis, iris coloboma, and early-onset retinal dystrophy, and dysplastic ears with abnormal external ear cartilage (summary by Gillespie et al., 2015).
See: Condition Record
Iris pigment epithelium anomalies
Oculoauricular syndrome

Professional guidelines

PubMed

Epithelial iris cyst treatment with intracystic ethanol irrigation.
Behrouzi Z, Khodadoust A
Ophthalmology 2003 Aug;110(8):1601-5. doi: 10.1016/s0161-6420(03)00543-8. PMID: 12917180
Iris cysts in children: classification, incidence, and management. The 1998 Torrence A Makley Jr Lecture.
Shields JA, Shields CL, Lois N, Mercado G
Br J Ophthalmol 1999 Mar;83(3):334-8. doi: 10.1136/bjo.83.3.334. PMID: 10365043Free PMC Article
The differential diagnosis of malignant melanoma of the iris. A clinical study of 200 patients.
Shields JA, Sanborn GE, Augsburger JJ
Ophthalmology 1983 Jun;90(6):716-20. doi: 10.1016/s0161-6420(83)34500-0. PMID: 6888862

Recent clinical studies

Etiology

Phacoemulsification in a patient with small pupil and a large iris cyst.
Rotsos T, Diagourtas A, Symeonidis C, Papaconstantinou D, Georgopoulos G
Eur J Ophthalmol 2012 Mar-Apr;22(2):278-9. doi: 10.5301/ejo.5000026. PMID: 21786265
Long-term follow-up and visual outcome after excision of a traumatic iris cyst by viscoelastic dissection.
Al-Ghadeer H, Al-Towerki AE, Al-Rajhi A, Al-Awad A
Int Ophthalmol 2011 Dec;31(6):529-31. Epub 2012 Jan 6 doi: 10.1007/s10792-011-9498-9. PMID: 22222716
Epithelial iris cyst treatment with intracystic ethanol irrigation.
Behrouzi Z, Khodadoust A
Ophthalmology 2003 Aug;110(8):1601-5. doi: 10.1016/s0161-6420(03)00543-8. PMID: 12917180
Iris cysts in children: classification, incidence, and management. The 1998 Torrence A Makley Jr Lecture.
Shields JA, Shields CL, Lois N, Mercado G
Br J Ophthalmol 1999 Mar;83(3):334-8. doi: 10.1136/bjo.83.3.334. PMID: 10365043Free PMC Article
Lack of association between iris color and primary iris cysts.
Kliman GH, Augsburger JJ, Shields JA
Am J Ophthalmol 1986 Jul 15;102(1):95-6. doi: 10.1016/0002-9394(86)90216-3. PMID: 3728632

Diagnosis

A Case of an Iris Cyst Not to Be Missed.
Betsch D, Gupta RR
JAMA Ophthalmol 2020 Jul 1;138(7):793-794. doi: 10.1001/jamaophthalmol.2020.0571. PMID: 32407442
Iris and ciliary body cysts and phakic intraocular lenses.
Gharaibeh AM, Liehneova I, Mojzis P, Ziak P, Alió JL
Eur J Ophthalmol 2020 Sep;30(5):974-977. Epub 2019 Sep 23 doi: 10.1177/1120672119876532. PMID: 31544491
Diagnosis of an Invisible Iris Cyst Using Autorefractometry and Anterior Segment Optical Coherence Tomography.
Müller TM, August P, Jesse M, Lange AP
Klin Monbl Augenheilkd 2017 Apr;234(4):604-605. Epub 2017 Mar 6 doi: 10.1055/s-0042-122913. PMID: 28264219
Peripheral pigmentary iris cyst: evaluation and differential diagnosis.
Minavi AZ, Holdeman NR
Clin Exp Optom 2007 Jan;90(1):49-52. doi: 10.1111/j.1444-0938.2006.00087.x. PMID: 17177666
Iris-cyst-simulating luxated lens.
Trivedi RH, Wilson ME Jr, Wells SA, Fraig MM
J Cataract Refract Surg 2006 Oct;32(10):1768-70. doi: 10.1016/j.jcrs.2006.05.022. PMID: 17010884

Therapy

Iris cyst after femtosecond laser-assisted cataract surgery: a case report.
Wu PY, Wu MH, Wu CC, Sun CC
BMC Ophthalmol 2021 Jan 13;21(1):36. doi: 10.1186/s12886-021-01803-y. PMID: 33441104Free PMC Article
A Case of Annular Iris Cyst Diagnosed With the Help of Ultrasound Biomicroscopy.
Segi A, Maheshwari D, Dabke S, Rao S, Kadar MA, Rengappa R
J Glaucoma 2020 Sep;29(9):e103-e105. doi: 10.1097/IJG.0000000000001612. PMID: 32694284
Iris cyst following cataract surgery.
Shah A, Rajesh PS, Dutta Majumder P
Clin Exp Optom 2020 Sep;103(5):701. Epub 2019 Nov 14 doi: 10.1111/cxo.13000. PMID: 31729772
Iris and ciliary body cysts and phakic intraocular lenses.
Gharaibeh AM, Liehneova I, Mojzis P, Ziak P, Alió JL
Eur J Ophthalmol 2020 Sep;30(5):974-977. Epub 2019 Sep 23 doi: 10.1177/1120672119876532. PMID: 31544491
Iris cyst after iris-sutured intraocular lens implantation in a child.
Wong RK, Salchow DJ
J AAPOS 2012 Apr;16(2):199-200. doi: 10.1016/j.jaapos.2011.12.147. PMID: 22525181

Prognosis

Iris and ciliary body cysts and phakic intraocular lenses.
Gharaibeh AM, Liehneova I, Mojzis P, Ziak P, Alió JL
Eur J Ophthalmol 2020 Sep;30(5):974-977. Epub 2019 Sep 23 doi: 10.1177/1120672119876532. PMID: 31544491
Cogan-Reese syndrome with Iris cyst: A novel presentation.
Selvan H, Brar AS, Angmo D
Cont Lens Anterior Eye 2019 Aug;42(4):467-469. Epub 2019 May 17 doi: 10.1016/j.clae.2019.04.014. PMID: 31104851
Long-term follow-up and visual outcome after excision of a traumatic iris cyst by viscoelastic dissection.
Al-Ghadeer H, Al-Towerki AE, Al-Rajhi A, Al-Awad A
Int Ophthalmol 2011 Dec;31(6):529-31. Epub 2012 Jan 6 doi: 10.1007/s10792-011-9498-9. PMID: 22222716
Iris cysts in children: classification, incidence, and management. The 1998 Torrence A Makley Jr Lecture.
Shields JA, Shields CL, Lois N, Mercado G
Br J Ophthalmol 1999 Mar;83(3):334-8. doi: 10.1136/bjo.83.3.334. PMID: 10365043Free PMC Article
Primary cysts of the iris.
Shields JA
Trans Am Ophthalmol Soc 1981;79:771-809. PMID: 7342411Free PMC Article

Clinical prediction guides

Management of an iris stromal cyst by fine needle aspiration with absolute alcohol irrigation and argon laser photocoagulation to induce sclerosis.
Vigués-Jorba L, Barnils N, Lorenzo D, Sanz S, Moix E, Caminal JM
J Fr Ophtalmol 2021 Sep;44(7):977-980. Epub 2021 Jun 17 doi: 10.1016/j.jfo.2020.12.019. PMID: 34147273
Iris and ciliary body cysts and phakic intraocular lenses.
Gharaibeh AM, Liehneova I, Mojzis P, Ziak P, Alió JL
Eur J Ophthalmol 2020 Sep;30(5):974-977. Epub 2019 Sep 23 doi: 10.1177/1120672119876532. PMID: 31544491
Iris cyst after iris-sutured intraocular lens implantation in a child.
Wong RK, Salchow DJ
J AAPOS 2012 Apr;16(2):199-200. doi: 10.1016/j.jaapos.2011.12.147. PMID: 22525181
Iris-cyst-simulating luxated lens.
Trivedi RH, Wilson ME Jr, Wells SA, Fraig MM
J Cataract Refract Surg 2006 Oct;32(10):1768-70. doi: 10.1016/j.jcrs.2006.05.022. PMID: 17010884
Primary cysts of the iris.
Shields JA
Trans Am Ophthalmol Soc 1981;79:771-809. PMID: 7342411Free PMC Article

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