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Physical addiction

MedGen UID:
124455
Concept ID:
C0278080
Mental or Behavioral Dysfunction
Synonyms: Physical Dependence; Physiological addiction
SNOMED CT: Physical addiction (41784005); Physiological addiction (41784005)

Definition

The neuroadaptation of the body to the presence of an opioid, and is characterized by the onset of acute symptoms and signs of withdrawal if the opioid is stopped or an opioid antagonist is administered. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhysical addiction

Professional guidelines

PubMed

Bavarian R, Khawaja SN, Treister NS
Oral Dis 2022 Apr;28(3):805-812. Epub 2021 Mar 9 doi: 10.1111/odi.13824. PMID: 33650141
Craig DS
J Pharm Pract 2012 Oct;25(5):510-6. Epub 2012 Jul 25 doi: 10.1177/0897190012453909. PMID: 22842507
Heit HA
Eur J Pain 2001;5 Suppl A:27-9. doi: 10.1053/eujp.2001.0276. PMID: 11798214

Recent clinical studies

Etiology

Benton D, Young HA
Int J Obes (Lond) 2016 Mar;40 Suppl 1(Suppl 1):S12-21. doi: 10.1038/ijo.2016.9. PMID: 27001642Free PMC Article
Wojas-Krawczyk K, Krawczyk P, Biernacka B, Grzybek M, Kołodziej P, Kucharczyk T, Mlak R, Milanowski J
Eur J Cancer Prev 2012 Mar;21(2):111-7. doi: 10.1097/CEJ.0b013e32834c9b40. PMID: 21955800
Leone A, Landini L, Leone A
Curr Pharm Des 2010;16(23):2510-7. doi: 10.2174/138161210792062948. PMID: 20550508
Henningfield JE, Rose CA, Zeller M
Tob Control 2006 Dec;15 Suppl 4(Suppl 4):iv27-36. doi: 10.1136/tc.2005.013789. PMID: 17130621Free PMC Article
Bourgois P, Martinez A, Kral A, Edlin BR, Schonberg J, Ciccarone D
PLoS Med 2006 Oct;3(10):e452. doi: 10.1371/journal.pmed.0030452. PMID: 17076569Free PMC Article

Diagnosis

Bavarian R, Khawaja SN, Treister NS
Oral Dis 2022 Apr;28(3):805-812. Epub 2021 Mar 9 doi: 10.1111/odi.13824. PMID: 33650141
Henningfield JE, Rose CA, Zeller M
Tob Control 2006 Dec;15 Suppl 4(Suppl 4):iv27-36. doi: 10.1136/tc.2005.013789. PMID: 17130621Free PMC Article
Lo SK, Wang CC, Fang W
Cyberpsychol Behav 2005 Feb;8(1):15-20. doi: 10.1089/cpb.2005.8.15. PMID: 15738689
Mather DB, Chinsky JM
J Subst Abuse 1996;8(1):81-91. doi: 10.1016/s0899-3289(96)90103-0. PMID: 8743770
Sellman D
Aust N Z J Psychiatry 1994 Jun;28(2):205-11. doi: 10.1080/00048679409075630. PMID: 7993274

Therapy

Agarwal A, Das M, Jaiswal PL, Kashyap P
J Cancer Res Ther 2023 Apr;19(Supplement):S0. doi: 10.4103/jcrt.jcrt_290_22. PMID: 37147969
Bavarian R, Khawaja SN, Treister NS
Oral Dis 2022 Apr;28(3):805-812. Epub 2021 Mar 9 doi: 10.1111/odi.13824. PMID: 33650141
Leone A, Landini L, Leone A
Curr Pharm Des 2010;16(23):2510-7. doi: 10.2174/138161210792062948. PMID: 20550508
Ramseier CA, Fundak A
Int J Dent Hyg 2009 Feb;7(1):39-48. doi: 10.1111/j.1601-5037.2008.00361.x. PMID: 19215310
Bourgois P, Martinez A, Kral A, Edlin BR, Schonberg J, Ciccarone D
PLoS Med 2006 Oct;3(10):e452. doi: 10.1371/journal.pmed.0030452. PMID: 17076569Free PMC Article

Prognosis

O'Loughlin J, Karp I, Koulis T, Paradis G, Difranza J
Am J Epidemiol 2009 Sep 1;170(5):585-97. Epub 2009 Jul 27 doi: 10.1093/aje/kwp179. PMID: 19635735
Gervais A, O'Loughlin J, Meshefedjian G, Bancej C, Tremblay M
CMAJ 2006 Aug 1;175(3):255-61. doi: 10.1503/cmaj.051235. PMID: 16880445Free PMC Article

Clinical prediction guides

Wojas-Krawczyk K, Krawczyk P, Biernacka B, Grzybek M, Kołodziej P, Kucharczyk T, Mlak R, Milanowski J
Eur J Cancer Prev 2012 Mar;21(2):111-7. doi: 10.1097/CEJ.0b013e32834c9b40. PMID: 21955800
Leone A, Landini L, Leone A
Curr Pharm Des 2010;16(23):2510-7. doi: 10.2174/138161210792062948. PMID: 20550508
Okoli CT, Richardson CG, Ratner PA, Johnson JL
Addict Behav 2009 Dec;34(12):1010-6. Epub 2009 Jul 5 doi: 10.1016/j.addbeh.2009.06.010. PMID: 19643546
O'Loughlin J, Karp I, Koulis T, Paradis G, Difranza J
Am J Epidemiol 2009 Sep 1;170(5):585-97. Epub 2009 Jul 27 doi: 10.1093/aje/kwp179. PMID: 19635735
Bourgois P, Martinez A, Kral A, Edlin BR, Schonberg J, Ciccarone D
PLoS Med 2006 Oct;3(10):e452. doi: 10.1371/journal.pmed.0030452. PMID: 17076569Free PMC Article

Recent systematic reviews

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