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Childhood Solid Neoplasm

MedGen UID:
124561
•Concept ID:
C0279068
•
Neoplastic Process
Synonyms: Childhood Solid Tumor; Pediatric Solid Tumor

Definition

A solid neoplasm (e.g., carcinoma, sarcoma) occurring in children. [from NCI]

Professional guidelines

PubMed

EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours.
Le Rhun E, Guckenberger M, Smits M, Dummer R, Bachelot T, Sahm F, Galldiks N, de Azambuja E, Berghoff AS, Metellus P, Peters S, Hong YK, Winkler F, Schadendorf D, van den Bent M, Seoane J, Stahel R, Minniti G, Wesseling P, Weller M, Preusser M; EANO Executive Board and ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2021 Nov;32(11):1332-1347. Epub 2021 Aug 6 doi: 10.1016/j.annonc.2021.07.016. PMID: 34364998
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article
Updates in Diagnosis, Management, and Treatment of Neuroblastoma.
Swift CC, Eklund MJ, Kraveka JM, Alazraki AL
Radiographics 2018 Mar-Apr;38(2):566-580. doi: 10.1148/rg.2018170132. PMID: 29528815

Recent clinical studies

Etiology

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Glypicans as Cancer Therapeutic Targets.
Li N, Gao W, Zhang YF, Ho M
Trends Cancer 2018 Nov;4(11):741-754. Epub 2018 Sep 28 doi: 10.1016/j.trecan.2018.09.004. PMID: 30352677Free PMC Article
Understanding medulloblastoma.
Quinlan A, Rizzolo D
JAAPA 2017 Oct;30(10):30-36. doi: 10.1097/01.JAA.0000524717.71084.50. PMID: 28953021
Why measure tumours?
Olsen ØE
Pediatr Radiol 2015 Jan;45(1):35-41. Epub 2015 Jan 1 doi: 10.1007/s00247-014-3148-0. PMID: 25552390Free PMC Article

Diagnosis

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Pediatric Neuro-Oncology.
Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Pediatric Brain Tumors.
Udaka YT, Packer RJ
Neurol Clin 2018 Aug;36(3):533-556. doi: 10.1016/j.ncl.2018.04.009. PMID: 30072070
Understanding medulloblastoma.
Quinlan A, Rizzolo D
JAAPA 2017 Oct;30(10):30-36. doi: 10.1097/01.JAA.0000524717.71084.50. PMID: 28953021

Therapy

Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
Parsons DW, Janeway KA, Patton DR, Winter CL, Coffey B, Williams PM, Roy-Chowdhuri S, Tsongalis GJ, Routbort M, Ramirez NC, Saguilig L, Piao J, Alonzo TA, Berg SL, Fox E, Hawkins DS, Abrams JS, Mooney M, Takebe N, Tricoli JV, Seibel NL; NCI-COG Pediatric MATCH Team
J Clin Oncol 2022 Jul 10;40(20):2224-2234. Epub 2022 Mar 30 doi: 10.1200/JCO.21.02838. PMID: 35353553Free PMC Article
Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article

Prognosis

DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma.
González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP
Mod Pathol 2022 Jan;35(1):4-22. Epub 2021 Oct 1 doi: 10.1038/s41379-021-00905-8. PMID: 34599283Free PMC Article
Pediatric Neuro-Oncology.
Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702
Neuroblastoma.
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764
Epidemiology of skin cancer.
Leiter U, Eigentler T, Garbe C
Adv Exp Med Biol 2014;810:120-40. doi: 10.1007/978-1-4939-0437-2_7. PMID: 25207363

Clinical prediction guides

Long-term survival and cure fraction estimates for childhood cancer in Europe (EUROCARE-6): results from a population-based study.
Botta L, Gatta G, Capocaccia R, Stiller C, Cañete A, Dal Maso L, Innos K, Mihor A, Erdmann F, Spix C, Lacour B, Marcos-Gragera R, Murray D, Rossi S; EUROCARE-6 Working Group
Lancet Oncol 2022 Dec;23(12):1525-1536. Epub 2022 Nov 16 doi: 10.1016/S1470-2045(22)00637-4. PMID: 36400102
The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models.
Kendsersky NM, Lindsay J, Kolb EA, Smith MA, Teicher BA, Erickson SW, Earley EJ, Mosse YP, Martinez D, Pogoriler J, Krytska K, Patel K, Groff D, Tsang M, Ghilu S, Wang Y, Seaman S, Feng Y, Croix BS, Gorlick R, Kurmasheva R, Houghton PJ, Maris JM
Clin Cancer Res 2021 May 15;27(10):2938-2946. Epub 2021 Feb 22 doi: 10.1158/1078-0432.CCR-20-4221. PMID: 33619171Free PMC Article
Congenital Neuroblastoma.
Minakova E, Lang J
Neoreviews 2020 Nov;21(11):e716-e727. doi: 10.1542/neo.21-11-e716. PMID: 33139509
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702

Recent systematic reviews

Dexrazoxane for preventing or reducing cardiotoxicity in adults and children with cancer receiving anthracyclines.
de Baat EC, Mulder RL, Armenian S, Feijen EA, Grotenhuis H, Hudson MM, Mavinkurve-Groothuis AM, Kremer LC, van Dalen EC
Cochrane Database Syst Rev 2022 Sep 27;9(9):CD014638. doi: 10.1002/14651858.CD014638.pub2. PMID: 36162822Free PMC Article
Maternal lifestyle factors and risk of neuroblastoma in the offspring: A meta-analysis including Greek NARECHEM-ST primary data.
Karalexi MA, Katsimpris A, Panagopoulou P, Bouka P, Schüz J, Ntzani E, Petridou ET; NARECHEM-ST collaborating group
Cancer Epidemiol 2022 Apr;77:102055. Epub 2022 Jan 11 doi: 10.1016/j.canep.2021.102055. PMID: 35026707
Risk factors for subsequent endocrine-related cancer in childhood cancer survivors.
Wijnen M, van den Heuvel-Eibrink MM, Medici M, Peeters RP, van der Lely AJ, Neggers SJ
Endocr Relat Cancer 2016 Jun;23(6):R299-321. Epub 2016 May 26 doi: 10.1530/ERC-16-0113. PMID: 27229933
Different dosage schedules for reducing cardiotoxicity in people with cancer receiving anthracycline chemotherapy.
van Dalen EC, van der Pal HJ, Kremer LC
Cochrane Database Syst Rev 2016 Mar 3;3(3):CD005008. doi: 10.1002/14651858.CD005008.pub4. PMID: 26938118Free PMC Article
Breast-feeding and childhood cancer: A systematic review with metaanalysis.
Martin RM, Gunnell D, Owen CG, Smith GD
Int J Cancer 2005 Dec 20;117(6):1020-31. doi: 10.1002/ijc.21274. PMID: 15986434

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