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Childhood Solid Neoplasm

MedGen UID:
124561
•Concept ID:
C0279068
•
Neoplastic Process
Synonyms: Childhood Solid Tumor; Pediatric Solid Tumor

Definition

A solid neoplasm (e.g., carcinoma, sarcoma) occurring in children. [from NCI]

Professional guidelines

PubMed

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article
Updates in Diagnosis, Management, and Treatment of Neuroblastoma.
Swift CC, Eklund MJ, Kraveka JM, Alazraki AL
Radiographics 2018 Mar-Apr;38(2):566-580. doi: 10.1148/rg.2018170132. PMID: 29528815

Recent clinical studies

Etiology

Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Pathology review and diagnostic approach.
Choi JH, Ro JY
Semin Diagn Pathol 2022 Mar;39(2):120-130. Epub 2021 Jun 15 doi: 10.1053/j.semdp.2021.06.007. PMID: 34167847
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Understanding medulloblastoma.
Quinlan A, Rizzolo D
JAAPA 2017 Oct;30(10):30-36. doi: 10.1097/01.JAA.0000524717.71084.50. PMID: 28953021
Why measure tumours?
Olsen ØE
Pediatr Radiol 2015 Jan;45(1):35-41. Epub 2015 Jan 1 doi: 10.1007/s00247-014-3148-0. PMID: 25552390Free PMC Article

Diagnosis

Mediastinal neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Pathology review and diagnostic approach.
Choi JH, Ro JY
Semin Diagn Pathol 2022 Mar;39(2):120-130. Epub 2021 Jun 15 doi: 10.1053/j.semdp.2021.06.007. PMID: 34167847
Pediatric Neuro-Oncology.
Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Pediatric Brain Tumors.
Udaka YT, Packer RJ
Neurol Clin 2018 Aug;36(3):533-556. doi: 10.1016/j.ncl.2018.04.009. PMID: 30072070
Understanding medulloblastoma.
Quinlan A, Rizzolo D
JAAPA 2017 Oct;30(10):30-36. doi: 10.1097/01.JAA.0000524717.71084.50. PMID: 28953021

Therapy

A Phase I/II Trial of Nivolumab plus Ipilimumab in Children and Young Adults with Relapsed/Refractory Solid Tumors: A Children's Oncology Group Study ADVL1412.
Davis KL, Fox E, Isikwei E, Reid JM, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Clin Cancer Res 2022 Dec 1;28(23):5088-5097. doi: 10.1158/1078-0432.CCR-22-2164. PMID: 36190525Free PMC Article
Association Between Radioactive Iodine Treatment for Pediatric and Young Adulthood Differentiated Thyroid Cancer and Risk of Second Primary Malignancies.
Pasqual E, Schonfeld S, Morton LM, Villoing D, Lee C, Berrington de Gonzalez A, Kitahara CM
J Clin Oncol 2022 May 1;40(13):1439-1449. Epub 2022 Jan 19 doi: 10.1200/JCO.21.01841. PMID: 35044839Free PMC Article
Pediatric Hepatocellular Carcinoma.
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699Free PMC Article

Prognosis

DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma.
González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP
Mod Pathol 2022 Jan;35(1):4-22. Epub 2021 Oct 1 doi: 10.1038/s41379-021-00905-8. PMID: 34599283Free PMC Article
Pediatric Neuro-Oncology.
Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389
Understanding medulloblastoma.
Quinlan A, Rizzolo D
JAAPA 2017 Oct;30(10):30-36. doi: 10.1097/01.JAA.0000524717.71084.50. PMID: 28953021
Neuroblastoma.
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764
Epidemiology of skin cancer.
Leiter U, Eigentler T, Garbe C
Adv Exp Med Biol 2014;810:120-40. doi: 10.1007/978-1-4939-0437-2_7. PMID: 25207363

Clinical prediction guides

Long-term survival and cure fraction estimates for childhood cancer in Europe (EUROCARE-6): results from a population-based study.
Botta L, Gatta G, Capocaccia R, Stiller C, Cañete A, Dal Maso L, Innos K, Mihor A, Erdmann F, Spix C, Lacour B, Marcos-Gragera R, Murray D, Rossi S; EUROCARE-6 Working Group
Lancet Oncol 2022 Dec;23(12):1525-1536. Epub 2022 Nov 16 doi: 10.1016/S1470-2045(22)00637-4. PMID: 36400102
A Phase I/II Trial of Nivolumab plus Ipilimumab in Children and Young Adults with Relapsed/Refractory Solid Tumors: A Children's Oncology Group Study ADVL1412.
Davis KL, Fox E, Isikwei E, Reid JM, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Clin Cancer Res 2022 Dec 1;28(23):5088-5097. doi: 10.1158/1078-0432.CCR-22-2164. PMID: 36190525Free PMC Article
Congenital Neuroblastoma.
Minakova E, Lang J
Neoreviews 2020 Nov;21(11):e716-e727. doi: 10.1542/neo.21-11-e716. PMID: 33139509
Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1-2 trial.
Davis KL, Fox E, Merchant MS, Reid JM, Kudgus RA, Liu X, Minard CG, Voss S, Berg SL, Weigel BJ, Mackall CL
Lancet Oncol 2020 Apr;21(4):541-550. Epub 2020 Mar 17 doi: 10.1016/S1470-2045(20)30023-1. PMID: 32192573Free PMC Article
Biological and Genetic Features of Neuroblastoma and Their Clinical Importance.
Aygun N
Curr Pediatr Rev 2018;14(2):73-90. doi: 10.2174/1573396314666180129101627. PMID: 29380702

Recent systematic reviews

Long-term cisplatin nephrotoxicity after childhood cancer: a systematic review and meta-analysis.
Schofield J, Harcus M, Pizer B, Jorgensen A, McWilliam S
Pediatr Nephrol 2024 Mar;39(3):699-710. Epub 2023 Sep 20 doi: 10.1007/s00467-023-06149-9. PMID: 37726572Free PMC Article
Dexrazoxane for preventing or reducing cardiotoxicity in adults and children with cancer receiving anthracyclines.
de Baat EC, Mulder RL, Armenian S, Feijen EA, Grotenhuis H, Hudson MM, Mavinkurve-Groothuis AM, Kremer LC, van Dalen EC
Cochrane Database Syst Rev 2022 Sep 27;9(9):CD014638. doi: 10.1002/14651858.CD014638.pub2. PMID: 36162822Free PMC Article
Maternal lifestyle factors and risk of neuroblastoma in the offspring: A meta-analysis including Greek NARECHEM-ST primary data.
Karalexi MA, Katsimpris A, Panagopoulou P, Bouka P, Schüz J, Ntzani E, Petridou ET; NARECHEM-ST collaborating group
Cancer Epidemiol 2022 Apr;77:102055. Epub 2022 Jan 11 doi: 10.1016/j.canep.2021.102055. PMID: 35026707
Risk factors for subsequent endocrine-related cancer in childhood cancer survivors.
Wijnen M, van den Heuvel-Eibrink MM, Medici M, Peeters RP, van der Lely AJ, Neggers SJ
Endocr Relat Cancer 2016 Jun;23(6):R299-321. Epub 2016 May 26 doi: 10.1530/ERC-16-0113. PMID: 27229933
Breast-feeding and childhood cancer: A systematic review with metaanalysis.
Martin RM, Gunnell D, Owen CG, Smith GD
Int J Cancer 2005 Dec 20;117(6):1020-31. doi: 10.1002/ijc.21274. PMID: 15986434

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