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Recurrent Urethral Carcinoma

MedGen UID:
124672
•Concept ID:
C0279912
•
Neoplastic Process
Synonyms: Recurrent Cancer of the Urethra; Recurrent Cancer of Urethra; Recurrent Urethra Cancer; Recurrent Urethra Carcinoma; Recurrent Urethral Cancer; Relapsed Cancer of the Urethra; Relapsed Cancer of Urethra; Relapsed Urethra Cancer; Relapsed Urethra Carcinoma; Relapsed Urethral Cancer; Urethral Cancer, Recurrent

Definition

The reemergence of urethral carcinoma after a period of remission [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Urethral Carcinoma

Professional guidelines

PubMed

Evaluation and management of urethral and periurethral masses in women.
Zuo SW, Napoe GS
Curr Opin Obstet Gynecol 2023 Dec 1;35(6):517-524. Epub 2023 Aug 29 doi: 10.1097/GCO.0000000000000914. PMID: 37678190
Management of Urethral Recurrences: Urothelial and Nonurothelial.
Zargar-Shoshtari K, Sexton WJ, Poch MA
Urol Clin North Am 2016 Nov;43(4):515-521. doi: 10.1016/j.ucl.2016.06.012. PMID: 27717437
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525

Recent clinical studies

Etiology

Clinical features and oncological outcomes of primary female urethral cancer.
Lee W, Yu J, Lee JL, Kim YS, Hong B
J Surg Oncol 2022 Apr;125(5):907-915. Epub 2022 Jan 20 doi: 10.1002/jso.26790. PMID: 35050502
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Urethral carcinoma in situ: recognition and management.
Berjeaut RH, Persaud MD, Sopko N, Burnett AL
Int Urol Nephrol 2017 Apr;49(4):637-641. Epub 2017 Jan 18 doi: 10.1007/s11255-017-1512-3. PMID: 28101735
Management of the Recurrent Male Urethral Stricture.
Zaid UB, Lavien G, Peterson AC
Curr Urol Rep 2016 Apr;17(4):33. doi: 10.1007/s11934-016-0588-0. PMID: 26902627
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Diagnosis

Evaluation and management of urethral and periurethral masses in women.
Zuo SW, Napoe GS
Curr Opin Obstet Gynecol 2023 Dec 1;35(6):517-524. Epub 2023 Aug 29 doi: 10.1097/GCO.0000000000000914. PMID: 37678190
Novel Noninvasive Diagnostics.
Wiley C, Wise CF, Breen M
Vet Clin North Am Small Anim Pract 2019 Sep;49(5):781-791. Epub 2019 Jul 4 doi: 10.1016/j.cvsm.2019.05.002. PMID: 31280902
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Therapy

Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Orthotopic neobladder after cystectomy for bladder cancer.
Kakizoe T
Proc Jpn Acad Ser B Phys Biol Sci 2020;96(7):255-265. doi: 10.2183/pjab.96.019. PMID: 32788549Free PMC Article
ICUD-SIU International Consultation on Bladder Cancer 2017: management of non-muscle invasive bladder cancer.
Monteiro LL, Witjes JA, Agarwal PK, Anderson CB, Bivalacqua TJ, Bochner BH, Boormans JL, Chang SS, Domínguez-Escrig JL, McKiernan JM, Dinney C, Godoy G, Kulkarni GS, Mariappan P, O'Donnell MA, Rentsch CA, Shah JB, Solsona E, Svatek RS, van der Heijden AG, van Valenberg FJP, Kassouf W
World J Urol 2019 Jan;37(1):51-60. Epub 2018 Aug 14 doi: 10.1007/s00345-018-2438-9. PMID: 30109483
Urethral recurrence after cystectomy: current preventative measures, diagnosis and management.
Chan Y, Fisher P, Tilki D, Evans CP
BJU Int 2016 Apr;117(4):563-9. Epub 2015 Dec 12 doi: 10.1111/bju.13370. PMID: 26556525
Superficial bladder cancer therapy.
Schenkman E, Lamm DL
ScientificWorldJournal 2004 Jun 28;4 Suppl 1:387-99. doi: 10.1100/tsw.2004.81. PMID: 15349563Free PMC Article

Prognosis

Tailor-made natural and synthetic grafts for precise urethral reconstruction.
Tan Q, Le H, Tang C, Zhang M, Yang W, Hong Y, Wang X
J Nanobiotechnology 2022 Aug 31;20(1):392. doi: 10.1186/s12951-022-01599-z. PMID: 36045428Free PMC Article
Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2022 Nov;129:71-80. Epub 2022 Aug 28 doi: 10.1016/j.humpath.2022.08.003. PMID: 36037997
Clinical features and oncological outcomes of primary female urethral cancer.
Lee W, Yu J, Lee JL, Kim YS, Hong B
J Surg Oncol 2022 Apr;125(5):907-915. Epub 2022 Jan 20 doi: 10.1002/jso.26790. PMID: 35050502
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768
Herpesvirus.
Baker DA
Clin Obstet Gynecol 1983 Mar;26(1):165-72. doi: 10.1097/00003081-198303000-00020. PMID: 6301717

Clinical prediction guides

Tailor-made natural and synthetic grafts for precise urethral reconstruction.
Tan Q, Le H, Tang C, Zhang M, Yang W, Hong Y, Wang X
J Nanobiotechnology 2022 Aug 31;20(1):392. doi: 10.1186/s12951-022-01599-z. PMID: 36045428Free PMC Article
The urethral plate and the underlying tissue; a histological and histochemical study.
Sennert M, Perske C, Wirmer J, Fawzy M, Hadidi AT
J Pediatr Urol 2022 Jun;18(3):364.e1-364.e9. Epub 2022 Feb 16 doi: 10.1016/j.jpurol.2022.02.006. PMID: 35249835
Clinical features and oncological outcomes of primary female urethral cancer.
Lee W, Yu J, Lee JL, Kim YS, Hong B
J Surg Oncol 2022 Apr;125(5):907-915. Epub 2022 Jan 20 doi: 10.1002/jso.26790. PMID: 35050502
Spotlight on gender-specific disparities in bladder cancer.
Mancini M, Righetto M, Baggio G
Urologia 2020 Aug;87(3):103-114. Epub 2019 Dec 23 doi: 10.1177/0391560319887327. PMID: 31868559
Photodynamic diagnosis in urology: state-of-the-art.
Jocham D, Stepp H, Waidelich R
Eur Urol 2008 Jun;53(6):1138-48. Epub 2007 Dec 10 doi: 10.1016/j.eururo.2007.11.048. PMID: 18096307

Recent systematic reviews

Systematic review and meta-analysis of randomized controlled trials of perioperative outcomes and prognosis of transurethral en-bloc resection vs. conventional transurethral resection for non-muscle-invasive bladder cancer.
Li Z, Zhou Z, Cui Y, Zhang Y
Int J Surg 2022 Aug;104:106777. Epub 2022 Jul 16 doi: 10.1016/j.ijsu.2022.106777. PMID: 35850465
Follow-up of the Urethra and Management of Urethral Recurrence After Radical Cystectomy: A Systematic Review and Proposal of Management Algorithm by the European Association of Urology-Young Academic Urologists: Urothelial Carcinoma Working Group.
Laukhtina E, Moschini M, Soria F, Andrea DD, Teoh JY, Mori K, Albisinni S, Mari A, Krajewski W, Cimadamore A, Abufaraj M, Enikeev D, Neuzillet Y, Giannarini G, Xylinas E, Kamat AM, Roupret M, Babjuk M, Witjes JA, Shariat SF, Pradere B; European Association of Urology; Young Academic Urologists EAU-YAU: Urothelial Carcinoma Working Group; European Association of Urology Section of Oncological Urology ESOU
Eur Urol Focus 2022 Nov;8(6):1635-1642. Epub 2022 Mar 23 doi: 10.1016/j.euf.2022.03.004. PMID: 35337773
Ureteral and urethral recurrence after radical cystectomy: a systematic review.
Carando R, Shariat SF, Moschini M, D'Andrea D
Curr Opin Urol 2020 May;30(3):441-448. doi: 10.1097/MOU.0000000000000752. PMID: 32235282
Urethral recurrence after radical cystectomy for urothelial carcinoma: A systematic review and meta-analysis.
Fahmy O, Khairul-Asri MG, Schubert T, Renninger M, Kübler H, Stenzl A, Gakis G
Urol Oncol 2018 Feb;36(2):54-59. Epub 2017 Nov 28 doi: 10.1016/j.urolonc.2017.11.007. PMID: 29196179
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article

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