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Bilateral breast carcinoma

MedGen UID:
128977
•Concept ID:
C0281267
•
Neoplastic Process
Synonyms: Bilateral Breast Cancer; Bilateral Breast Carcinoma; bilateral breast carcinoma
 
Monarch Initiative: MONDO:0003982

Definition

Carcinoma that affects both breasts in a simultaneous or non-simultaneous manner. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Bilateral breast carcinoma

Professional guidelines

PubMed

Bilateral Breast Cancer-Its clinicopathological profile and management: An experience from a tertiary care center from Eastern India.
Mishra S, Sable M, Das Majumdar SK, Mishra P, Muduly DK, Parida DK
J Cancer Res Ther 2022 Dec;18(Supplement):S341-S346. doi: 10.4103/jcrt.JCRT_1729_20. PMID: 36510986
Simultaneous integrated boost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy.
Nicolini G, Clivio A, Fogliata A, Vanetti E, Cozzi L
Radiat Oncol 2009 Jul 24;4:27. doi: 10.1186/1748-717X-4-27. PMID: 19630947Free PMC Article
The impact of stage and treatment modality on the likelihood of second malignancies and hematopoietic disorders in Hodgkin's disease.
Mendenhall NP, Shuster JJ, Million RR
Radiother Oncol 1989 Mar;14(3):219-29. doi: 10.1016/0167-8140(89)90170-9. PMID: 2710953

Recent clinical studies

Etiology

Bilateral Breast Cancer-Its clinicopathological profile and management: An experience from a tertiary care center from Eastern India.
Mishra S, Sable M, Das Majumdar SK, Mishra P, Muduly DK, Parida DK
J Cancer Res Ther 2022 Dec;18(Supplement):S341-S346. doi: 10.4103/jcrt.JCRT_1729_20. PMID: 36510986
Synchronous bilateral breast carcinoma irradiation: A comparative investigation between flattened and unflattened beams.
Duan S, Li C, Shi J, Ma Y, Zhang X, Huang J, Wu X, Lin X, Huang X
Appl Radiat Isot 2022 Mar;181:110079. Epub 2022 Jan 5 doi: 10.1016/j.apradiso.2021.110079. PMID: 35016153
Radiation therapy of synchronous bilateral breast carcinoma (SBBC) using multiple techniques.
Kim SJ, Lee MJ, Youn SM
Med Dosim 2018 Spring;43(1):55-68. Epub 2017 Oct 5 doi: 10.1016/j.meddos.2017.08.003. PMID: 28988893
Bilateral breast carcinoma: clinical characteristics and its impact on survival.
Vuoto HD, García AM, Candás GB, Zimmermann AG, Uriburu JL, Isetta JA, Cogorno L, Khoury M, Bernabó OL
Breast J 2010 Nov-Dec;16(6):625-32. doi: 10.1111/j.1524-4741.2010.00976.x. PMID: 21070440
Bilateral breast carcinoma: mammographic and histologic correlation.
Murphy TJ, Conant EF, Hanau CA, Ehrlich SM, Feig SA
Radiology 1995 Jun;195(3):617-21. doi: 10.1148/radiology.195.3.7753983. PMID: 7753983

Diagnosis

Bilateral Breast Cancer-Its clinicopathological profile and management: An experience from a tertiary care center from Eastern India.
Mishra S, Sable M, Das Majumdar SK, Mishra P, Muduly DK, Parida DK
J Cancer Res Ther 2022 Dec;18(Supplement):S341-S346. doi: 10.4103/jcrt.JCRT_1729_20. PMID: 36510986
Properties of Synchronous Versus Metachronous Bilateral Breast Carcinoma with Long Time Follow Up.
Eliyatkin N, Zengel B, Yagci A, Comut E, Postaci H, Uslu A, Aktas S
Asian Pac J Cancer Prev 2015;16(12):4921-6. doi: 10.7314/apjcp.2015.16.12.4921. PMID: 26163616
Bilateral breast carcinoma: clinical characteristics and its impact on survival.
Vuoto HD, García AM, Candás GB, Zimmermann AG, Uriburu JL, Isetta JA, Cogorno L, Khoury M, Bernabó OL
Breast J 2010 Nov-Dec;16(6):625-32. doi: 10.1111/j.1524-4741.2010.00976.x. PMID: 21070440
Diagnostic and prognostic utility of molecular markers in synchronous bilateral breast carcinoma.
Saad RS, Denning KL, Finkelstein SD, Liu Y, Pereira TC, Lin X, Silverman JF
Mod Pathol 2008 Oct;21(10):1200-7. Epub 2008 May 9 doi: 10.1038/modpathol.2008.35. PMID: 18469799
Bilateral breast carcinoma: risk factors and outcomes for patients with synchronous and metachronous disease.
Heron DE, Komarnicky LT, Hyslop T, Schwartz GF, Mansfield CM
Cancer 2000 Jun 15;88(12):2739-50. PMID: 10870056

Therapy

Tamoxifen related Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT): A case report and literature review of this possible association.
Segala D, Gobbo S, Pesci A, Martignoni G, Santoro A, Angelico G, Arciuolo D, Spadola S, Valente M, Scambia G, Zannoni GF
Pathol Res Pract 2019 May;215(5):1089-1092. Epub 2019 Jan 28 doi: 10.1016/j.prp.2019.01.039. PMID: 30799070
Radiation therapy of synchronous bilateral breast carcinoma (SBBC) using multiple techniques.
Kim SJ, Lee MJ, Youn SM
Med Dosim 2018 Spring;43(1):55-68. Epub 2017 Oct 5 doi: 10.1016/j.meddos.2017.08.003. PMID: 28988893
Bilateral breast carcinoma after radiation therapy for Hodgkin's disease.
Colvett KT
South Med J 1995 Feb;88(2):239-42. doi: 10.1097/00007611-199502000-00017. PMID: 7839173
Simultaneous bilateral breast carcinomas: a retrospective review of 149 cases.
de la Rochefordiere A, Asselain B, Scholl S, Campana F, Ucla L, Vilcoq JR, Durand JC, Pouillart P, Fourquet A
Int J Radiat Oncol Biol Phys 1994 Aug 30;30(1):35-41. doi: 10.1016/0360-3016(94)90516-9. PMID: 8083126
The impact of stage and treatment modality on the likelihood of second malignancies and hematopoietic disorders in Hodgkin's disease.
Mendenhall NP, Shuster JJ, Million RR
Radiother Oncol 1989 Mar;14(3):219-29. doi: 10.1016/0167-8140(89)90170-9. PMID: 2710953

Prognosis

Properties of Synchronous Versus Metachronous Bilateral Breast Carcinoma with Long Time Follow Up.
Eliyatkin N, Zengel B, Yagci A, Comut E, Postaci H, Uslu A, Aktas S
Asian Pac J Cancer Prev 2015;16(12):4921-6. doi: 10.7314/apjcp.2015.16.12.4921. PMID: 26163616
Primary squamous cell carcinoma of the breast after cured bilateral breast cancer.
Porzio R, Cordini C, Orsi N, Brigati F, Paties CT, Cavanna L
In Vivo 2014 Nov-Dec;28(6):1155-8. PMID: 25398815
Diagnostic and prognostic utility of molecular markers in synchronous bilateral breast carcinoma.
Saad RS, Denning KL, Finkelstein SD, Liu Y, Pereira TC, Lin X, Silverman JF
Mod Pathol 2008 Oct;21(10):1200-7. Epub 2008 May 9 doi: 10.1038/modpathol.2008.35. PMID: 18469799
Bilateral breast carcinoma: risk factors and outcomes for patients with synchronous and metachronous disease.
Heron DE, Komarnicky LT, Hyslop T, Schwartz GF, Mansfield CM
Cancer 2000 Jun 15;88(12):2739-50. PMID: 10870056
Bilateral breast carcinoma treated with definitive irradiation.
Solin LJ, Fowble BL, Schultz DJ, Goodman RL
Int J Radiat Oncol Biol Phys 1989 Aug;17(2):263-71. doi: 10.1016/0360-3016(89)90438-0. PMID: 2546905

Clinical prediction guides

Periductal stromal tumor of the breast with synchronous bilateral breast cancer.
Ki SY, Lim HS, Lee JS, Park SY, Yim NY, Heo SH, Park MH, Cho JS, Shin SH
Anticancer Res 2014 Jul;34(7):3635-9. PMID: 24982380
Contralateral prophylactic mastectomy in an Asian population: a single institution review.
Sim Y, Tan VK, Ho GH, Wong CY, Madhukumar P, Tan BK, Yong WS, Ng YY, Ong KW
Breast 2014 Feb;23(1):56-62. Epub 2013 Nov 23 doi: 10.1016/j.breast.2013.10.008. PMID: 24275318
High risk of contralateral breast carcinoma in women with hereditary/familial non-BRCA1/BRCA2 breast carcinoma.
Shahedi K, Emanuelsson M, Wiklund F, Gronberg H
Cancer 2006 Mar 15;106(6):1237-42. doi: 10.1002/cncr.21753. PMID: 16475207
A Ser49Cys variant in the ataxia telangiectasia, mutated, gene that is more common in patients with breast carcinoma compared with population controls.
Buchholz TA, Weil MM, Ashorn CL, Strom EA, Sigurdson A, Bondy M, Chakraborty R, Cox JD, McNeese MD, Story MD
Cancer 2004 Apr 1;100(7):1345-51. doi: 10.1002/cncr.20133. PMID: 15042666
Histological grade, p53, HER2 and hormone receptor status of synchronous bilateral breast carcinoma.
Matsuo K, Fukutomi T, Akashi-Tanaka S, Hasegawa T, Tsuda H
Breast Cancer 2002;9(2):127-33. doi: 10.1007/BF02967577. PMID: 12016392

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