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Paroxysmal sneezing

MedGen UID:
1369153
Concept ID:
C0858634
Finding
HPO: HP:0025096

Definition

Unprovoked explosive pathological sneezing. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParoxysmal sneezing

Conditions with this feature

Achoo syndrome
MedGen UID:
400287
Concept ID:
C1863416
Disease or Syndrome
Autosomal Dominant Compelling Helioopthalmic Outburst (ACHOO) Syndrome is characterized by uncontrollable sneezing in response to the sudden exposure to bright light, typically intense sunlight. This type of sneezing is also known as photic sneezing. About one in four individuals who already have a prickling sensation in their nose will sneeze in response to sunlight, but “pure” photic sneezing is far less common. Sneezing is usually triggered by contact with infectious agents or after inhaling irritants, but the cause of photic sneezing is not fully understood. It may involve an over-excitability of the visual cortex in response to light, leading to a stronger activation of the secondary somatosensory areas.

Professional guidelines

PubMed

Mao D, He Z, Li L, Lei Y, Xiao M, Zhang H, Zhang F
J Healthc Eng 2022;2022:3594210. Epub 2022 Apr 11 doi: 10.1155/2022/3594210. PMID: 35444784Free PMC Article
Mistry J, Heneghan NR, Noblet T, Falla D, Rushton A
BMC Musculoskelet Disord 2020 Aug 10;21(1):532. doi: 10.1186/s12891-020-03436-6. PMID: 32778086Free PMC Article
Castillo J, Dimov V
Expert Opin Investig Drugs 2014 Jun;23(6):823-36. Epub 2014 Apr 8 doi: 10.1517/13543784.2014.907271. PMID: 24708183

Recent clinical studies

Etiology

Harmancı K, Urhan B, Anıl H, Kocak A
Int Forum Allergy Rhinol 2015 Feb;5(2):143-8. Epub 2014 Dec 12 doi: 10.1002/alr.21455. PMID: 25504747
Payne S, Tisch S, Cole I, Brake H, Rough J, Darveniza P
Mov Disord 2014 May;29(6):729-35. Epub 2014 Apr 18 doi: 10.1002/mds.25865. PMID: 24753288
Leung AK, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2008 Nov;2(3):175-85. doi: 10.2174/187221308786241965. PMID: 19076007
Chantzi FM, Kafetzis DA, Bairamis T, Avramidou C, Paleologou N, Grimani I, Apostolopoulos N, Papadopoulos NG
Allergy 2006 Mar;61(3):332-6. doi: 10.1111/j.1398-9995.2006.00971.x. PMID: 16436142
Pedersen PA, Weeke ER
Allergy 1981 Aug;36(6):375-9. doi: 10.1111/j.1398-9995.1981.tb01841.x. PMID: 7316106

Diagnosis

Harmancı K, Urhan B, Anıl H, Kocak A
Int Forum Allergy Rhinol 2015 Feb;5(2):143-8. Epub 2014 Dec 12 doi: 10.1002/alr.21455. PMID: 25504747
Chantzi FM, Kafetzis DA, Bairamis T, Avramidou C, Paleologou N, Grimani I, Apostolopoulos N, Papadopoulos NG
Allergy 2006 Mar;61(3):332-6. doi: 10.1111/j.1398-9995.2006.00971.x. PMID: 16436142
Lin TJ, Maccia CA, Turnier CG
Ann Allergy Asthma Immunol 2003 Dec;91(6):575-8. doi: 10.1016/S1081-1206(10)61537-2. PMID: 14700443
Gopalan P, Browning ST
J Laryngol Otol 2002 Nov;116(11):958-9. doi: 10.1258/00222150260369543. PMID: 12487679
Butani L, O'Connell EJ
Ann Allergy Asthma Immunol 1997 Aug;79(2):91-9; quiz 99-101. doi: 10.1016/S1081-1206(10)63094-3. PMID: 9291412

Therapy

Harmancı K, Urhan B, Anıl H, Kocak A
Int Forum Allergy Rhinol 2015 Feb;5(2):143-8. Epub 2014 Dec 12 doi: 10.1002/alr.21455. PMID: 25504747
Payne S, Tisch S, Cole I, Brake H, Rough J, Darveniza P
Mov Disord 2014 May;29(6):729-35. Epub 2014 Apr 18 doi: 10.1002/mds.25865. PMID: 24753288
Leung AK, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2013 Sep;7(3):187-201. doi: 10.2174/1872213x113079990022. PMID: 23829414
Leung AK, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2008 Nov;2(3):175-85. doi: 10.2174/187221308786241965. PMID: 19076007
Lin TJ, Maccia CA, Turnier CG
Ann Allergy Asthma Immunol 2003 Dec;91(6):575-8. doi: 10.1016/S1081-1206(10)61537-2. PMID: 14700443

Prognosis

Chantzi FM, Kafetzis DA, Bairamis T, Avramidou C, Paleologou N, Grimani I, Apostolopoulos N, Papadopoulos NG
Allergy 2006 Mar;61(3):332-6. doi: 10.1111/j.1398-9995.2006.00971.x. PMID: 16436142
Wiener D, McGrath K, Patterson R
J Allergy Clin Immunol 1985 Jun;75(6):741-2. doi: 10.1016/0091-6749(85)90104-6. PMID: 4008804

Clinical prediction guides

Payne S, Tisch S, Cole I, Brake H, Rough J, Darveniza P
Mov Disord 2014 May;29(6):729-35. Epub 2014 Apr 18 doi: 10.1002/mds.25865. PMID: 24753288
Yonekura S, Okamoto Y, Okubo K, Okawa T, Gotoh M, Suzuki H, Kakuma T, Horiguchi S, Hanazawa T, Konno A, Okuda M
J Investig Allergol Clin Immunol 2009;19(3):195-203. PMID: 19610262
Wiener D, McGrath K, Patterson R
J Allergy Clin Immunol 1985 Jun;75(6):741-2. doi: 10.1016/0091-6749(85)90104-6. PMID: 4008804

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