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Increased number of elastic fibers in the dermis

MedGen UID:
1370308
•Concept ID:
C4476629
•
Finding
Synonym: Increased number of elastic fibres in the dermis
 
HPO: HP:0025164

Definition

An elevated number of elastic fibers, that is of bundles of proteins and glycoproteins in the extracellular matrix in the reticular dermis. Elastic fibers can stretch and recoil back to their original length. This feature can be appreciated on histology with hematoxylin and eosin or other staining methods. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased number of elastic fibers in the dermis

Professional guidelines

PubMed

Dermal changes in osteoporosis following prolonged treatment with human growth hormone.
Aloia JF, Grover RW
J Cutan Pathol 1976;3(5):222-31. doi: 10.1111/j.1600-0560.1976.tb00867.x. PMID: 1018062

Recent clinical studies

Etiology

Histological and morphological development of the prepuce from birth to prepubertal age.
Erdem E, Caliskan MK, Karagul MI, Akbay E, Coskun Yilmaz B, Aygun YC
Investig Clin Urol 2024 Mar;65(2):180-188. doi: 10.4111/icu.20230034. PMID: 38454828Free PMC Article
Morphea after Silicone Implants.
Wollina U, Schönlebe J
Acta Dermatovenerol Croat 2023 Aug;31(1):45-47. PMID: 37843092
Hairstyling Practices to Prevent Hair Damage and Alopecia in Women of African Descent.
Geisler AN, Oyerinde O, Scott DA
Cutis 2022 Feb;109(2):98-100. doi: 10.12788/cutis.0444. PMID: 35659800
Analyses of changes on skin by aging.
Kazanci A, Kurus M, Atasever A
Skin Res Technol 2017 Feb;23(1):48-60. Epub 2016 Jun 20 doi: 10.1111/srt.12300. PMID: 27321201
Effects of isoflavones on the skin of postmenopausal women: a pilot study.
Accorsi-Neto A, Haidar M, Simões R, Simões M, Soares J Jr, Baracat E
Clinics (Sao Paulo) 2009;64(6):505-10. doi: 10.1590/s1807-59322009000600004. PMID: 19578653Free PMC Article

Diagnosis

Morphea after Silicone Implants.
Wollina U, Schönlebe J
Acta Dermatovenerol Croat 2023 Aug;31(1):45-47. PMID: 37843092
Idiopathic atrophoderma of Pasini and Pierini: A case study of collagen and elastin texture by multiphoton microscopy.
Vieira-Damiani G, Lage D, Christofoletti Daldon PÉ, Tibúrcio Alves CR, Cintra ML, Metze K, Adur J, Pelegati VB, Carvalho HF, Cesar CL
J Am Acad Dermatol 2017 Nov;77(5):930-937. Epub 2017 Apr 25 doi: 10.1016/j.jaad.2017.02.044. PMID: 28389037
Skin aging in patients with acquired immunodeficiency syndrome.
de Aquino Favarato GK, da Silva AC, Oliveira LF, da Fonseca Ferraz ML, de Paula Antunes Teixeira V, Cavellani CL
Ann Diagn Pathol 2016 Oct;24:35-9. Epub 2016 Aug 12 doi: 10.1016/j.anndiagpath.2016.07.004. PMID: 27649952
Acrokeratoelastoidosis.
Tsai S, Kageyama N, Warthan M, Cockerell CJ
Int J Dermatol 2005 May;44(5):406-7. doi: 10.1111/j.1365-4632.2005.01980.x. PMID: 15869538
Nephrogenic fibrosing dermopathy.
Cowper SE, Su LD, Bhawan J, Robin HS, LeBoit PE
Am J Dermatopathol 2001 Oct;23(5):383-93. doi: 10.1097/00000372-200110000-00001. PMID: 11801769

Therapy

Morphea after Silicone Implants.
Wollina U, Schönlebe J
Acta Dermatovenerol Croat 2023 Aug;31(1):45-47. PMID: 37843092
Hairstyling Practices to Prevent Hair Damage and Alopecia in Women of African Descent.
Geisler AN, Oyerinde O, Scott DA
Cutis 2022 Feb;109(2):98-100. doi: 10.12788/cutis.0444. PMID: 35659800
Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study.
Siperstein R, Wikramanayake TC
Lasers Surg Med 2021 Sep;53(7):926-934. Epub 2020 Dec 8 doi: 10.1002/lsm.23358. PMID: 33615512
The benefit of daily photoprotection.
Seité S, Fourtanier AM
J Am Acad Dermatol 2008 May;58(5 Suppl 2):S160-6. doi: 10.1016/j.jaad.2007.04.036. PMID: 18410803
Acrokeratoelastoidosis.
Tsai S, Kageyama N, Warthan M, Cockerell CJ
Int J Dermatol 2005 May;44(5):406-7. doi: 10.1111/j.1365-4632.2005.01980.x. PMID: 15869538

Prognosis

Pseudoxanthoma Elasticum-Like Papillary Dermal Elastolysis: A Single Case Report.
Valbuena V, Assaad D, Yeung J
J Cutan Med Surg 2017 Jul/Aug;21(4):345-347. Epub 2017 Mar 10 doi: 10.1177/1203475417699407. PMID: 28282240
Ectopic calcification in β-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylation.
Boraldi F, Garcia-Fernandez M, Paolinelli-Devincenzi C, Annovi G, Schurgers L, Vermeer C, Cianciulli P, Ronchetti I, Quaglino D
Biochim Biophys Acta 2013 Dec;1832(12):2077-84. Epub 2013 Jul 27 doi: 10.1016/j.bbadis.2013.07.017. PMID: 23899606
Histologic effects of the high-energy pulsed CO2 laser on photoaged facial skin.
Stuzin JM, Baker TJ, Baker TM, Kligman AM
Plast Reconstr Surg 1997 Jun;99(7):2036-50; discussion 2051-5. doi: 10.1097/00006534-199706000-00034. PMID: 9180729

Clinical prediction guides

Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study.
Siperstein R, Wikramanayake TC
Lasers Surg Med 2021 Sep;53(7):926-934. Epub 2020 Dec 8 doi: 10.1002/lsm.23358. PMID: 33615512
Effects of isoflavones on the skin of postmenopausal women: a pilot study.
Accorsi-Neto A, Haidar M, Simões R, Simões M, Soares J Jr, Baracat E
Clinics (Sao Paulo) 2009;64(6):505-10. doi: 10.1590/s1807-59322009000600004. PMID: 19578653Free PMC Article
The benefit of daily photoprotection.
Seité S, Fourtanier AM
J Am Acad Dermatol 2008 May;58(5 Suppl 2):S160-6. doi: 10.1016/j.jaad.2007.04.036. PMID: 18410803
Familial cutaneous collagenoma.
Dawn ME, Deng AC, Petrali J, Wessely C, Jaffe D, Gaspari AA
Skinmed 2008 Jan-Feb;7(1):43-5. doi: 10.1111/j.1540-9740.2007.06353.x. PMID: 18174804
Colloid and elastic fibre: ultrastructural study on the histogenesis of colloid milium.
Kobayashi H, Hashimoto K
J Cutan Pathol 1983 Apr;10(2):111-22. doi: 10.1111/j.1600-0560.1983.tb01484.x. PMID: 6853793

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