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Abnormal bronchus morphology

MedGen UID:: 1371523
•Concept ID:: C4476770
•: Anatomical Abnormality

Synonym:	Abnormality of the bronchi

HPO:	HP:0025426

Definition

Any structural anomaly of the bronchi, i.e., of the airways leading from the trachea to the lungs. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal bronchus morphology

Phenotypic abnormality
- Abnormality of the respiratory system
  - Abnormal respiratory system morphology
    - Abnormal tracheobronchial morphology
      - Abnormal bronchus morphology
        Accessory cardiac bronchus
        Airway casts
        Fibrin casts
        Mucin casts
        Bronchial atresia
        Bronchial cartilage hypoplasia
        Bronchial diverticula
        Bronchial hemorrhage
        Bronchial wall thickening
        Bronchiectasis
        Idiopathic bronchiectasis
        Bronchiectasis with or without elevated sweat chloride 1
        Bronchiectasis with or without elevated sweat chloride 2
        Bronchiectasis with or without elevated sweat chloride 3
        Bronchiolectasis
        Bronchodysplasia
        Bronchomalacia
        Tracheobronchomalacia
        Cartilaginous tracheobronchomalacia
        Excessive dynamic airway collapse
        Tracheomalacia
        Bronchomegaly
        Increased airway neuroendocrine cells
        Increased airway neuroepithelial bodies
        Recurrent bronchitis
        Recurrent bronchiolitis
        Tracheal bronchus
        Displaced lobar tracheal bronchus
        Displaced tracheal bronchus
        Supernumerary tracheal bronchus
        Traction bronchiectasis
        Traction bronchiolectasis

Professional guidelines

PubMed

Tracheobronchomalacia, Tracheobronchial Compression, and Tracheobronchial Malformations: Diagnostic and Treatment Strategies.

Kamran A, Baird CW, Jennings RW
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020;23:53-61. doi: 10.1053/j.pcsu.2020.02.006. PMID: 32354548

Congenital bronchial atresia: diagnosis and treatment.

Wang Y, Dai W, Sun Y, Chu X, Yang B, Zhao M
Int J Med Sci 2012;9(3):207-12. Epub 2012 Mar 3 doi: 10.7150/ijms.3690. PMID: 22408569 Free PMC Article

Horseshoe lung: differential diagnosis.

Hawass ND, Badawi MG, al-Muzrakchi AM, al-Sammarai AI, Jawad AJ, Abdullah MA, Bahakim H
Pediatr Radiol 1990;20(8):580-4. doi: 10.1007/BF02129059. PMID: 2251000

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Recent clinical studies

Etiology

Malignancy in the tracheal bronchus: A case series and review of the literature.

Levin E, Bowling MR
Clin Respir J 2018 Sep;12(9):2441-2445. doi: 10.1111/crj.12943. PMID: 30015374

Small airway disease in asthma: pathophysiological and diagnostic considerations.

Contoli M, Santus P, Papi A
Curr Opin Pulm Med 2015 Jan;21(1):68-73. doi: 10.1097/MCP.0000000000000122. PMID: 25415403

Multislice CT in congenital bronchopulmonary malformations in children.

Tomà P, Rizzo F, Stagnaro N, Magnano G, Granata C
Radiol Med 2011 Feb;116(1):133-51. Epub 2010 Sep 17 doi: 10.1007/s11547-010-0582-4. PMID: 20852957

The pathophysiology of bronchiectasis.

King PT
Int J Chron Obstruct Pulmon Dis 2009;4:411-9. Epub 2009 Nov 29 doi: 10.2147/copd.s6133. PMID: 20037680 Free PMC Article

Middle lobe syndrome.

Wagner RB, Johnston MR
Ann Thorac Surg 1983 Jun;35(6):679-86. doi: 10.1016/s0003-4975(10)61085-5. PMID: 6344820

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Diagnosis

Neonatal Laryngotracheal Anomalies.

Gallant JN, Ransom M, Kaspar A, Wilcox LJ, Whigham AS, Engelstad HJ
Neoreviews 2022 Sep 1;23(9):e613-e624. doi: 10.1542/neo.23-9-e613. PMID: 36047759

Overview and Challenges of Bronchiolar Disorders.

Swaminathan AC, Carney JM, Tailor TD, Palmer SM
Ann Am Thorac Soc 2020 Mar;17(3):253-263. doi: 10.1513/AnnalsATS.201907-569CME. PMID: 31860801

Pig bronchus.

Han J, Xiang H, Ridley WE, Ridley LJ
J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:34. doi: 10.1111/1754-9485.21_12785. PMID: 30309104

Tracheobronchomalacia.

Biswas A, Jantz MA, Sriram PS, Mehta HJ
Dis Mon 2017 Oct;63(10):287-302. Epub 2017 May 23 doi: 10.1016/j.disamonth.2017.04.003. PMID: 28549723

Tracheal bronchus.

Barat M, Konrad HR
Am J Otolaryngol 1987 Mar-Apr;8(2):118-22. doi: 10.1016/s0196-0709(87)80034-0. PMID: 3592078

See all (898)

Therapy

The emerging spectrum of exposure-related bronchiolitis.

Krefft SD, Cool CD, Rose CS
Curr Opin Allergy Clin Immunol 2018 Apr;18(2):87-95. doi: 10.1097/ACI.0000000000000425. PMID: 29394172

Initial LDCT appearance of incident lung cancers in the ITALUNG trial.

Mascalchi M, Picozzi G, Falchini M, Vella A, Diciotti S, Carrozzi L, Pegna AL, Falaschi F
Eur J Radiol 2014 Nov;83(11):2080-6. Epub 2014 Aug 12 doi: 10.1016/j.ejrad.2014.07.019. PMID: 25174775

Fatal aortobronchial fistula.

Li M, Langlois N, Byard RW
J Forensic Leg Med 2013 Jul;20(5):395-8. Epub 2012 Aug 22 doi: 10.1016/j.jflm.2012.07.008. PMID: 23756504

Lung cancer preneoplasia.

Wistuba II, Gazdar AF
Annu Rev Pathol 2006;1:331-48. doi: 10.1146/annurev.pathol.1.110304.100103. PMID: 18039118

Morphological and cellular basis for airflow limitation in smokers.

Saetta M, Finkelstein R, Cosio MG
Eur Respir J 1994 Aug;7(8):1505-15. doi: 10.1183/09031936.94.07081505. PMID: 7957838

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Prognosis

Novel Artificial Intelligence-based Technology for Chest Computed Tomography Analysis of Idiopathic Pulmonary Fibrosis.

Handa T, Tanizawa K, Oguma T, Uozumi R, Watanabe K, Tanabe N, Niwamoto T, Shima H, Mori R, Nobashi TW, Sakamoto R, Kubo T, Kurosaki A, Kishi K, Nakamoto Y, Hirai T
Ann Am Thorac Soc 2022 Mar;19(3):399-406. doi: 10.1513/AnnalsATS.202101-044OC. PMID: 34410886

The emerging spectrum of exposure-related bronchiolitis.

Krefft SD, Cool CD, Rose CS
Curr Opin Allergy Clin Immunol 2018 Apr;18(2):87-95. doi: 10.1097/ACI.0000000000000425. PMID: 29394172

Pulmonary mucosa-associated lymphoid tissue lymphoma revisited.

Borie R, Wislez M, Antoine M, Copie-Bergman C, Thieblemont C, Cadranel J
Eur Respir J 2016 Apr;47(4):1244-60. Epub 2016 Jan 21 doi: 10.1183/13993003.01701-2015. PMID: 26797028

Initial LDCT appearance of incident lung cancers in the ITALUNG trial.

Mascalchi M, Picozzi G, Falchini M, Vella A, Diciotti S, Carrozzi L, Pegna AL, Falaschi F
Eur J Radiol 2014 Nov;83(11):2080-6. Epub 2014 Aug 12 doi: 10.1016/j.ejrad.2014.07.019. PMID: 25174775

Bronchopulmonary foregut malformations: embryology, radiology and quandary.

Barnes NA, Pilling DW
Eur Radiol 2003 Dec;13(12):2659-73. Epub 2003 Feb 12 doi: 10.1007/s00330-002-1812-5. PMID: 14631525

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Clinical prediction guides

Novel Artificial Intelligence-based Technology for Chest Computed Tomography Analysis of Idiopathic Pulmonary Fibrosis.

Congenital tracheobronchial stenosis.

Hewitt RJ, Butler CR, Maughan EF, Elliott MJ
Semin Pediatr Surg 2016 Jun;25(3):144-9. Epub 2016 Feb 19 doi: 10.1053/j.sempedsurg.2016.02.007. PMID: 27301600

Initial LDCT appearance of incident lung cancers in the ITALUNG trial.

Mascalchi M, Picozzi G, Falchini M, Vella A, Diciotti S, Carrozzi L, Pegna AL, Falaschi F
Eur J Radiol 2014 Nov;83(11):2080-6. Epub 2014 Aug 12 doi: 10.1016/j.ejrad.2014.07.019. PMID: 25174775

Mounier-Kuhn syndrome.

Simon M, Vremaroiu P, Andrei F
J Bronchology Interv Pulmonol 2014 Apr;21(2):145-9. doi: 10.1097/LBR.0000000000000068. PMID: 24739689

A new classification for right top pulmonary vein.

Akiba T, Morikawa T, Inagaki T, Nakada T, Ohki T
Ann Thorac Surg 2013 Apr;95(4):1227-30. Epub 2013 Feb 21 doi: 10.1016/j.athoracsur.2013.01.011. PMID: 23434252

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Recent systematic reviews

Congenital Anomalies of the Tracheobronchial Tree: A Meta-Analysis and Clinical Considerations.

Wong LM, Cheruiyot I, de Oliveira MHS, Keet K, Tomaszewski KA, Walocha JA, Tubbs S, Henry BM
Ann Thorac Surg 2021 Jul;112(1):315-325. Epub 2020 Nov 4 doi: 10.1016/j.athoracsur.2020.08.060. PMID: 33159867

Congenital bronchopulmonary foregut malformation: systematic review of the literature.

Yang G, Chen L, Xu C, Yuan M, Li Y
BMC Pediatr 2019 Sep 2;19(1):305. doi: 10.1186/s12887-019-1686-1. PMID: 31477056 Free PMC Article

Nasal versus tracheobronchial biopsies to diagnose primary ciliary dyskinesia: A meta-analysis.

Adil EA, Kawai K, Dombrowski N, Irace AL, Cunningham MJ
Laryngoscope 2017 Jan;127(1):6-13. Epub 2016 Jun 16 doi: 10.1002/lary.26070. PMID: 27312809

Imaging evaluation of pediatric trachea and bronchi: systematic review and updates.

Lee EY, Restrepo R, Dillman JR, Ridge CA, Hammer MR, Boiselle PM
Semin Roentgenol 2012 Apr;47(2):182-96. doi: 10.1053/j.ro.2011.12.002. PMID: 22370196

Kommerell's diverticulum and right-sided aortic arch: a cohort study and review of the literature.

Cinà CS, Althani H, Pasenau J, Abouzahr L
J Vasc Surg 2004 Jan;39(1):131-9. doi: 10.1016/j.jvs.2003.07.021. PMID: 14718830

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Abnormal bronchus morphology

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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