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Infratentorial and Spinal Cord Ependymal Tumor

MedGen UID:
1372129
•Concept ID:
C4330490
•
Neoplastic Process

Definition

A finding indicating the presence of an ependymal tumor in the infratentorial region of the brain and spinal cord. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfratentorial and Spinal Cord Ependymal Tumor

Recent clinical studies

Etiology

Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond.
Kresbach C, Neyazi S, Schüller U
Brain Pathol 2022 Jul;32(4):e13068. Epub 2022 Mar 21 doi: 10.1111/bpa.13068. PMID: 35307892Free PMC Article
Utility of copy number variants in the classification of intracranial ependymoma.
Evenson M, Cai C, Hucthagowder V, McNulty S, Neidich J, Kulkarni S, Dahiya S
Cancer Genet 2020 Jan;240:66-72. Epub 2019 Nov 18 doi: 10.1016/j.cancergen.2019.11.003. PMID: 31794935
Pediatric tumors of the central nervous system: a retrospective study of 1,043 cases from a tertiary care center in South India.
Asirvatham JR, Deepti AN, Chyne R, Prasad MS, Chacko AG, Rajshekhar V, Chacko G
Childs Nerv Syst 2011 Aug;27(8):1257-63. Epub 2011 Feb 23 doi: 10.1007/s00381-011-1407-z. PMID: 21344241
Epidemiology of nervous system tumors in children: a survey of 1,485 cases in Beijing Tiantan Hospital from 2001 to 2005.
Zhou D, Zhang Y, Liu H, Luo S, Luo L, Dai K
Pediatr Neurosurg 2008;44(2):97-103. Epub 2008 Jan 24 doi: 10.1159/000113110. PMID: 18230922
Subependymoma revisited: clinicopathological evaluation of 83 cases.
Rushing EJ, Cooper PB, Quezado M, Begnami M, Crespo A, Smirniotopoulos JG, Ecklund J, Olsen C, Santi M
J Neurooncol 2007 Dec;85(3):297-305. Epub 2007 Jun 14 doi: 10.1007/s11060-007-9411-6. PMID: 17569000

Diagnosis

Ependymomas in Children and Adults.
Lampros M, Vlachos N, Alexiou GA
Adv Exp Med Biol 2023;1405:99-116. doi: 10.1007/978-3-031-23705-8_4. PMID: 37452936
Utility of copy number variants in the classification of intracranial ependymoma.
Evenson M, Cai C, Hucthagowder V, McNulty S, Neidich J, Kulkarni S, Dahiya S
Cancer Genet 2020 Jan;240:66-72. Epub 2019 Nov 18 doi: 10.1016/j.cancergen.2019.11.003. PMID: 31794935
Epidemiology of nervous system tumors in children: a survey of 1,485 cases in Beijing Tiantan Hospital from 2001 to 2005.
Zhou D, Zhang Y, Liu H, Luo S, Luo L, Dai K
Pediatr Neurosurg 2008;44(2):97-103. Epub 2008 Jan 24 doi: 10.1159/000113110. PMID: 18230922
Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age.
Korshunov A, Neben K, Wrobel G, Tews B, Benner A, Hahn M, Golanov A, Lichter P
Am J Pathol 2003 Nov;163(5):1721-7. doi: 10.1016/S0002-9440(10)63530-4. PMID: 14578171Free PMC Article
Ependymomas and ependymoblastomas in children.
Dohrmann GJ, Farwell JR, Flannery JT
J Neurosurg 1976 Sep;45(3):273-83. doi: 10.3171/jns.1976.45.3.0273. PMID: 948014

Prognosis

Ependymomas in Children and Adults.
Lampros M, Vlachos N, Alexiou GA
Adv Exp Med Biol 2023;1405:99-116. doi: 10.1007/978-3-031-23705-8_4. PMID: 37452936
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond.
Kresbach C, Neyazi S, Schüller U
Brain Pathol 2022 Jul;32(4):e13068. Epub 2022 Mar 21 doi: 10.1111/bpa.13068. PMID: 35307892Free PMC Article
Utility of copy number variants in the classification of intracranial ependymoma.
Evenson M, Cai C, Hucthagowder V, McNulty S, Neidich J, Kulkarni S, Dahiya S
Cancer Genet 2020 Jan;240:66-72. Epub 2019 Nov 18 doi: 10.1016/j.cancergen.2019.11.003. PMID: 31794935
Subependymoma revisited: clinicopathological evaluation of 83 cases.
Rushing EJ, Cooper PB, Quezado M, Begnami M, Crespo A, Smirniotopoulos JG, Ecklund J, Olsen C, Santi M
J Neurooncol 2007 Dec;85(3):297-305. Epub 2007 Jun 14 doi: 10.1007/s11060-007-9411-6. PMID: 17569000
Ependymomas and ependymoblastomas in children.
Dohrmann GJ, Farwell JR, Flannery JT
J Neurosurg 1976 Sep;45(3):273-83. doi: 10.3171/jns.1976.45.3.0273. PMID: 948014

Clinical prediction guides

Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond.
Kresbach C, Neyazi S, Schüller U
Brain Pathol 2022 Jul;32(4):e13068. Epub 2022 Mar 21 doi: 10.1111/bpa.13068. PMID: 35307892Free PMC Article
Epidemiology of nervous system tumors in children: a survey of 1,485 cases in Beijing Tiantan Hospital from 2001 to 2005.
Zhou D, Zhang Y, Liu H, Luo S, Luo L, Dai K
Pediatr Neurosurg 2008;44(2):97-103. Epub 2008 Jan 24 doi: 10.1159/000113110. PMID: 18230922
Ependymomas of childhood. I. Histological survey and clinicopathological correlation.
Liu HM, Boogs J, Kidd J
Childs Brain 1976;2(2):92-110. PMID: 971635

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