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No hair follicle formation

MedGen UID:
1372377
•Concept ID:
C4479042
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNo hair follicle formation

Professional guidelines

PubMed

Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review.
Völker JM, Koch N, Becker M, Klenk A
Skin Pharmacol Physiol 2020;33(3):93-109. Epub 2020 Jun 29 doi: 10.1159/000508228. PMID: 32599587
Acne, the Skin Microbiome, and Antibiotic Treatment.
Xu H, Li H
Am J Clin Dermatol 2019 Jun;20(3):335-344. doi: 10.1007/s40257-018-00417-3. PMID: 30632097Free PMC Article
Microneedling for the treatment of hair loss?
Fertig RM, Gamret AC, Cervantes J, Tosti A
J Eur Acad Dermatol Venereol 2018 Apr;32(4):564-569. Epub 2017 Dec 21 doi: 10.1111/jdv.14722. PMID: 29194786

Recent clinical studies

Etiology

Acne, the Skin Microbiome, and Antibiotic Treatment.
Xu H, Li H
Am J Clin Dermatol 2019 Jun;20(3):335-344. doi: 10.1007/s40257-018-00417-3. PMID: 30632097Free PMC Article
Alopecia areata: A multifactorial autoimmune condition.
Simakou T, Butcher JP, Reid S, Henriquez FL
J Autoimmun 2019 Mar;98:74-85. Epub 2018 Dec 15 doi: 10.1016/j.jaut.2018.12.001. PMID: 30558963
Genetic and molecular aspects of androgenetic alopecia.
Martinez-Jacobo L, Villarreal-Villarreal CD, Ortiz-López R, Ocampo-Candiani J, Rojas-Martínez A
Indian J Dermatol Venereol Leprol 2018 May-Jun;84(3):263-268. doi: 10.4103/ijdvl.IJDVL_262_17. PMID: 29595184
Acne vulgaris.
Moradi Tuchayi S, Makrantonaki E, Ganceviciene R, Dessinioti C, Feldman SR, Zouboulis CC
Nat Rev Dis Primers 2015 Sep 17;1:15029. doi: 10.1038/nrdp.2015.29. PMID: 27189872
Folliculitis: recognition and management.
Luelmo-Aguilar J, Santandreu MS
Am J Clin Dermatol 2004;5(5):301-10. doi: 10.2165/00128071-200405050-00003. PMID: 15554731

Diagnosis

Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia.
Moon IJ, Yoon HK, Kim D, Choi ME, Han SH, Park JH, Hong SW, Cho H, Lee DK, Won CH
Mol Pharm 2023 Jan 2;20(1):128-135. Epub 2022 Nov 9 doi: 10.1021/acs.molpharmaceut.2c00510. PMID: 36352823Free PMC Article
Androgens in women: Androgen-mediated skin disease and patient evaluation.
Bienenfeld A, Azarchi S, Lo Sicco K, Marchbein S, Shapiro J, Nagler AR
J Am Acad Dermatol 2019 Jun;80(6):1497-1506. Epub 2018 Oct 10 doi: 10.1016/j.jaad.2018.08.062. PMID: 30312644
Androgenetic alopecia.
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Folliculitis: recognition and management.
Luelmo-Aguilar J, Santandreu MS
Am J Clin Dermatol 2004;5(5):301-10. doi: 10.2165/00128071-200405050-00003. PMID: 15554731
Albinism.
King RA, Summers CG
Dermatol Clin 1988 Apr;6(2):217-28. PMID: 3288382

Therapy

Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review.
Völker JM, Koch N, Becker M, Klenk A
Skin Pharmacol Physiol 2020;33(3):93-109. Epub 2020 Jun 29 doi: 10.1159/000508228. PMID: 32599587
Acne, the Skin Microbiome, and Antibiotic Treatment.
Xu H, Li H
Am J Clin Dermatol 2019 Jun;20(3):335-344. doi: 10.1007/s40257-018-00417-3. PMID: 30632097Free PMC Article
Alopecia areata: A multifactorial autoimmune condition.
Simakou T, Butcher JP, Reid S, Henriquez FL
J Autoimmun 2019 Mar;98:74-85. Epub 2018 Dec 15 doi: 10.1016/j.jaut.2018.12.001. PMID: 30558963
Genetic and molecular aspects of androgenetic alopecia.
Martinez-Jacobo L, Villarreal-Villarreal CD, Ortiz-López R, Ocampo-Candiani J, Rojas-Martínez A
Indian J Dermatol Venereol Leprol 2018 May-Jun;84(3):263-268. doi: 10.4103/ijdvl.IJDVL_262_17. PMID: 29595184
Acne vulgaris.
Moradi Tuchayi S, Makrantonaki E, Ganceviciene R, Dessinioti C, Feldman SR, Zouboulis CC
Nat Rev Dis Primers 2015 Sep 17;1:15029. doi: 10.1038/nrdp.2015.29. PMID: 27189872

Prognosis

Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases.
Ober-Reynolds B, Wang C, Ko JM, Rios EJ, Aasi SZ, Davis MM, Oro AE, Greenleaf WJ
Nat Genet 2023 Aug;55(8):1288-1300. Epub 2023 Jul 27 doi: 10.1038/s41588-023-01445-4. PMID: 37500727
EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis.
Nanba D, Toki F, Asakawa K, Matsumura H, Shiraishi K, Sayama K, Matsuzaki K, Toki H, Nishimura EK
J Cell Biol 2021 Nov 1;220(11) Epub 2021 Sep 22 doi: 10.1083/jcb.202012073. PMID: 34550317Free PMC Article
The hair follicle enigma.
Bernard BA
Exp Dermatol 2017 Jun;26(6):472-477. Epub 2017 May 9 doi: 10.1111/exd.13337. PMID: 28266743
Androgenetic alopecia.
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Skin of color: biology, structure, function, and implications for dermatologic disease.
Taylor SC
J Am Acad Dermatol 2002 Feb;46(2 Suppl Understanding):S41-62. doi: 10.1067/mjd.2002.120790. PMID: 11807469

Clinical prediction guides

Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases.
Ober-Reynolds B, Wang C, Ko JM, Rios EJ, Aasi SZ, Davis MM, Oro AE, Greenleaf WJ
Nat Genet 2023 Aug;55(8):1288-1300. Epub 2023 Jul 27 doi: 10.1038/s41588-023-01445-4. PMID: 37500727
Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia.
Moon IJ, Yoon HK, Kim D, Choi ME, Han SH, Park JH, Hong SW, Cho H, Lee DK, Won CH
Mol Pharm 2023 Jan 2;20(1):128-135. Epub 2022 Nov 9 doi: 10.1021/acs.molpharmaceut.2c00510. PMID: 36352823Free PMC Article
EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis.
Nanba D, Toki F, Asakawa K, Matsumura H, Shiraishi K, Sayama K, Matsuzaki K, Toki H, Nishimura EK
J Cell Biol 2021 Nov 1;220(11) Epub 2021 Sep 22 doi: 10.1083/jcb.202012073. PMID: 34550317Free PMC Article
Regeneration of fat cells from myofibroblasts during wound healing.
Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G
Science 2017 Feb 17;355(6326):748-752. Epub 2017 Jan 5 doi: 10.1126/science.aai8792. PMID: 28059714Free PMC Article
Skin of color: biology, structure, function, and implications for dermatologic disease.
Taylor SC
J Am Acad Dermatol 2002 Feb;46(2 Suppl Understanding):S41-62. doi: 10.1067/mjd.2002.120790. PMID: 11807469

Recent systematic reviews

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review.
Krefft-Trzciniecka K, Piętowska Z, Nowicka D, Szepietowski JC
Cells 2023 Mar 21;12(6) doi: 10.3390/cells12060951. PMID: 36980291Free PMC Article
Antimicrobial peptides in hidradenitis suppurativa: a systematic review.
Yao Y, Frew JW, Thomsen SF, Ring HC
Br J Dermatol 2022 Feb;186(2):236-244. Epub 2021 Nov 2 doi: 10.1111/bjd.20750. PMID: 34498267
The expression of opsins in the human skin and its implications for photobiomodulation: A Systematic Review.
Suh S, Choi EH, Atanaskova Mesinkovska N
Photodermatol Photoimmunol Photomed 2020 Sep;36(5):329-338. Epub 2020 Jun 1 doi: 10.1111/phpp.12578. PMID: 32431001Free PMC Article
The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis.
Pavlović RT, Janković SM, Milovanović JR, Stefanović SM, Folić MM, Milovanović OZ, Mamillapalli C, Milosavljević MN
Clin Breast Cancer 2019 Dec;19(6):e731-e740. Epub 2019 Aug 21 doi: 10.1016/j.clbc.2019.07.007. PMID: 31522958
Dermatosurgical techniques for repigmentation of vitiligo.
Rusfianti M, Wirohadidjodjo YW
Int J Dermatol 2006 Apr;45(4):411-7. doi: 10.1111/j.1365-4632.2006.02486.x. PMID: 16650168

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