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Fibrinogen deficiency

MedGen UID:
1372663
Concept ID:
C4316812
Disease or Syndrome
Synonyms: Deficiency, Fibrinogen; Fibrinogen Deficiencies; Fibrinogen Deficiency
SNOMED CT: Fibrinogen deficiency (359727008)

Definition

A usually inherited blood coagulation disorder characterized by the partial or complete absence of fibrinogen in the blood, resulting in bleeding. [from NCI]

Professional guidelines

PubMed

Tanaka KA, Bader SO, Görlinger K
Curr Opin Anaesthesiol 2014 Feb;27(1):72-80. doi: 10.1097/ACO.0000000000000025. PMID: 24263685
Peyvandi F
Thromb Res 2012 Dec;130 Suppl 2:S7-11. doi: 10.1016/S0049-3848(13)70004-5. PMID: 23439004
Tziomalos K, Vakalopoulou S, Perifanis V, Garipidou V
Vasc Health Risk Manag 2009;5:843-8. Epub 2009 Oct 12 doi: 10.2147/vhrm.s5305. PMID: 19851522Free PMC Article

Recent clinical studies

Therapy

Davenport R, Curry N, Fox EE, Thomas H, Lucas J, Evans A, Shanmugaranjan S, Sharma R, Deary A, Edwards A, Green L, Wade CE, Benger JR, Cotton BA, Stanworth SJ, Brohi K; CRYOSTAT-2 Principal Investigators
JAMA 2023 Nov 21;330(19):1882-1891. doi: 10.1001/jama.2023.21019. PMID: 37824155Free PMC Article
Hofer S, Blaha J, Collins PW, Ducloy-Bouthors AS, Guasch E, Labate F, Lança F, Nyfløt LT, Steiner K, Van de Velde M
Eur J Anaesthesiol 2023 Jan 1;40(1):29-38. Epub 2022 Sep 22 doi: 10.1097/EJA.0000000000001744. PMID: 36131564Free PMC Article
John MJ, Byreddy P, Modak K, Makkar M
Acta Haematol 2021;144(6):595-602. Epub 2021 Jun 4 doi: 10.1159/000516339. PMID: 34091452
Grottke O, Mallaiah S, Karkouti K, Saner F, Haas T
Semin Thromb Hemost 2020 Feb;46(1):38-49. Epub 2019 Oct 1 doi: 10.1055/s-0039-1696946. PMID: 31574543
Peyvandi F, Cattaneo M, Inbal A, De Moerloose P, Spreafico M
Haemophilia 2008 Jul;14 Suppl 3:202-10. doi: 10.1111/j.1365-2516.2008.01751.x. PMID: 18510543

Prognosis

Ranucci M, Di Dedda U, Baryshnikova E
Anesth Analg 2020 Mar;130(3):644-653. doi: 10.1213/ANE.0000000000004522. PMID: 31725023
Peng HT, Nascimento B, Beckett A
Biomed Res Int 2018;2018:7020539. Epub 2018 Nov 25 doi: 10.1155/2018/7020539. PMID: 30596098Free PMC Article
Bannow BS, Konkle BA
Transfus Med Rev 2018 Oct;32(4):237-243. Epub 2018 Jul 12 doi: 10.1016/j.tmrv.2018.06.003. PMID: 30097224
Collis R, Guasch E
Best Pract Res Clin Anaesthesiol 2017 Mar;31(1):107-124. Epub 2017 Feb 9 doi: 10.1016/j.bpa.2017.02.001. PMID: 28625299
Iwaki T, Castellino FJ
Curr Drug Targets 2005 Aug;6(5):535-9. doi: 10.2174/1389450054546006. PMID: 16026273

Clinical prediction guides

Mohsenian S, Palla R, Menegatti M, Cairo A, Lecchi A, Casini A, Neerman-Arbez M, Asselta R, Scardo S, Siboni SM, Blatny J, Zapletal O, Schved JF, Giansily-Blaizot M, Halimeh S, Daoud MA, Platokouki H, Pergantou H, Schutgens REG, Van Haaften-Spoor M, Brons P, Laros-van Gorkom B, Van Pinxten E, Borhany M, Fatima N, Mikovic D, Saracevic M, Özdemir GN, Ay Y, Makris M, Lockley C, Mumford A, Harvey A, Austin S, Shapiro A, Williamson A, McGuinn C, Goldberg I, De Moerloose P, Peyvandi F
Blood Adv 2024 Mar 26;8(6):1392-1404. doi: 10.1182/bloodadvances.2023012186. PMID: 38286442Free PMC Article
Davenport R, Curry N, Fox EE, Thomas H, Lucas J, Evans A, Shanmugaranjan S, Sharma R, Deary A, Edwards A, Green L, Wade CE, Benger JR, Cotton BA, Stanworth SJ, Brohi K; CRYOSTAT-2 Principal Investigators
JAMA 2023 Nov 21;330(19):1882-1891. doi: 10.1001/jama.2023.21019. PMID: 37824155Free PMC Article
Ranucci M, Di Dedda U, Baryshnikova E
Anesth Analg 2020 Mar;130(3):644-653. doi: 10.1213/ANE.0000000000004522. PMID: 31725023
Peng HT, Nascimento B, Beckett A
Biomed Res Int 2018;2018:7020539. Epub 2018 Nov 25 doi: 10.1155/2018/7020539. PMID: 30596098Free PMC Article
Collis R, Guasch E
Best Pract Res Clin Anaesthesiol 2017 Mar;31(1):107-124. Epub 2017 Feb 9 doi: 10.1016/j.bpa.2017.02.001. PMID: 28625299

Recent systematic reviews

van Meegeren ME, de Rooy JW, Schreuder HW, Brons PP
Haemophilia 2014 Mar;20(2):244-8. Epub 2013 Nov 29 doi: 10.1111/hae.12337. PMID: 24533951
Schoot RA, Kremer LC, van de Wetering MD, van Ommen CH
Cochrane Database Syst Rev 2013 Sep 11;(9):CD009160. doi: 10.1002/14651858.CD009160.pub2. PMID: 24026801
Bornikova L, Peyvandi F, Allen G, Bernstein J, Manco-Johnson MJ
J Thromb Haemost 2011 Sep;9(9):1687-704. doi: 10.1111/j.1538-7836.2011.04424.x. PMID: 21711446

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