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Childhood supratentorial embryonal tumor with multilayered rosettes, C19MC-altered

MedGen UID:
1375924
Concept ID:
C4316809
Neoplastic Process
Synonyms: Childhood Supratentorial Embryonal Tumor with Multilayered Rosettes, C19MC-Altered; childhood supratentorial embryonal tumor with multilayered rosettes, C19MC-altered; Childhood Supratentorial Ependymoblastoma; Pediatric Supratentorial Ependymoblastoma
 
Monarch Initiative: MONDO:0850388

Definition

An embryonal tumor with multilayered rosettes, C19MC-altered that arises from the supratentorial brain and occurs in children. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood supratentorial embryonal tumor with multilayered rosettes, C19MC-altered

Professional guidelines

PubMed

Reddy AT
Curr Neurol Neurosci Rep 2001 Mar;1(2):137-43. doi: 10.1007/s11910-001-0009-7. PMID: 11898509
Bonner K, Siegel KR
J Neurosci Nurs 1988 Apr;20(2):84-93. doi: 10.1097/01376517-198804000-00004. PMID: 2966218
Wilson CB
Cancer 1975 Mar;35(3 suppl):950-6. doi: 10.1002/1097-0142(197503)35:3+<950::aid-cncr2820350716>3.0.co;2-l. PMID: 1167486

Recent clinical studies

Etiology

Wimberly CE, Gulrajani NB, Russ JB, Landi D, Wiemels JL, Towry L, Wiencke JK, Walsh KM
Cancer Epidemiol Biomarkers Prev 2024 Mar 1;33(3):347-354. doi: 10.1158/1055-9965.EPI-23-1027. PMID: 38112788Free PMC Article
Tanem KE, Stensvold E, Wilberg P, Skaare AB, Brandal P, Herlofson BB
Support Care Cancer 2022 Dec;30(12):10233-10241. Epub 2022 Oct 29 doi: 10.1007/s00520-022-07405-8. PMID: 36307656Free PMC Article
Kvammen JA, Stensvold E, Godang K, Bollerslev J, Myklebust TÅ, Brandal P, Henriksen C, Bechensteen AG
Clin Nutr ESPEN 2022 Aug;50:162-169. Epub 2022 Jun 4 doi: 10.1016/j.clnesp.2022.05.025. PMID: 35871919
Shalaby T, Fiaschetti G, Baumgartner M, Grotzer MA
Molecules 2014 May 6;19(5):5821-62. doi: 10.3390/molecules19055821. PMID: 24806581Free PMC Article
Gilles FH, Sobel EL, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman L, Sobel RA
J Neurooncol 1992 Jun;13(2):137-49. doi: 10.1007/BF00172763. PMID: 1432031

Diagnosis

Schepke E, Löfgren M, Pietsch T, Kling T, Nordborg C, Olsson Bontell T, Holm S, Öberg A, Nyman P, Eliasson-Hofvander M, Sabel M, Lannering B, Carén H
Clin Epigenetics 2023 Mar 9;15(1):40. doi: 10.1186/s13148-023-01456-2. PMID: 36895035Free PMC Article
Kvammen JA, Stensvold E, Godang K, Bollerslev J, Myklebust TÅ, Brandal P, Henriksen C, Bechensteen AG
Clin Nutr ESPEN 2022 Aug;50:162-169. Epub 2022 Jun 4 doi: 10.1016/j.clnesp.2022.05.025. PMID: 35871919
Tanem KE, Stensvold E, Wilberg P, Skaare AB, Singh PB, Brandal P, Herlofson BB
Support Care Cancer 2022 Jul;30(7):6155-6162. Epub 2022 Apr 15 doi: 10.1007/s00520-022-07048-9. PMID: 35426047Free PMC Article
Shalaby T, Fiaschetti G, Baumgartner M, Grotzer MA
Molecules 2014 May 6;19(5):5821-62. doi: 10.3390/molecules19055821. PMID: 24806581Free PMC Article
Gilles FH, Sobel EL, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman L, Sobel RA
J Neurooncol 1992 Jun;13(2):137-49. doi: 10.1007/BF00172763. PMID: 1432031

Therapy

Ajithkumar T, Avanzo M, Yorke E, Tsang DS, Milano MT, Olch AJ, Merchant TE, Dieckmann K, Mahajan A, Fuji H, Paulino AC, Timmermann B, Marks LB, Bentzen SM, Jackson A, Constine LS
Int J Radiat Oncol Biol Phys 2024 Jun 1;119(2):655-668. Epub 2024 Feb 1 doi: 10.1016/j.ijrobp.2023.12.043. PMID: 38300187
Wimberly CE, Gulrajani NB, Russ JB, Landi D, Wiemels JL, Towry L, Wiencke JK, Walsh KM
Cancer Epidemiol Biomarkers Prev 2024 Mar 1;33(3):347-354. doi: 10.1158/1055-9965.EPI-23-1027. PMID: 38112788Free PMC Article
Saran F
Curr Opin Neurol 2002 Dec;15(6):671-7. doi: 10.1097/01.wco.0000044762.39452.e3. PMID: 12447104
Reddy AT
Curr Neurol Neurosci Rep 2001 Mar;1(2):137-43. doi: 10.1007/s11910-001-0009-7. PMID: 11898509
Bonner K, Siegel KR
J Neurosci Nurs 1988 Apr;20(2):84-93. doi: 10.1097/01376517-198804000-00004. PMID: 2966218

Prognosis

Schepke E, Löfgren M, Pietsch T, Kling T, Nordborg C, Olsson Bontell T, Holm S, Öberg A, Nyman P, Eliasson-Hofvander M, Sabel M, Lannering B, Carén H
Clin Epigenetics 2023 Mar 9;15(1):40. doi: 10.1186/s13148-023-01456-2. PMID: 36895035Free PMC Article
Shalaby T, Fiaschetti G, Baumgartner M, Grotzer MA
Molecules 2014 May 6;19(5):5821-62. doi: 10.3390/molecules19055821. PMID: 24806581Free PMC Article
Reddy AT
Curr Neurol Neurosci Rep 2001 Mar;1(2):137-43. doi: 10.1007/s11910-001-0009-7. PMID: 11898509
Gilles FH, Leviton A, Hedley-Whyte ET, Sobel E, Tavaré CJ, Sobel RS, Rorke LB
J Neurooncol 1992 Sep;14(1):45-56. doi: 10.1007/BF00170944. PMID: 1469464
Gilles FH, Sobel EL, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman L, Sobel RA
J Neurooncol 1992 Jun;13(2):137-49. doi: 10.1007/BF00172763. PMID: 1432031

Clinical prediction guides

Schepke E, Löfgren M, Pietsch T, Kling T, Nordborg C, Olsson Bontell T, Holm S, Öberg A, Nyman P, Eliasson-Hofvander M, Sabel M, Lannering B, Carén H
Clin Epigenetics 2023 Mar 9;15(1):40. doi: 10.1186/s13148-023-01456-2. PMID: 36895035Free PMC Article
Tanem KE, Stensvold E, Wilberg P, Skaare AB, Brandal P, Herlofson BB
Support Care Cancer 2022 Dec;30(12):10233-10241. Epub 2022 Oct 29 doi: 10.1007/s00520-022-07405-8. PMID: 36307656Free PMC Article
Kvammen JA, Stensvold E, Godang K, Bollerslev J, Myklebust TÅ, Brandal P, Henriksen C, Bechensteen AG
Clin Nutr ESPEN 2022 Aug;50:162-169. Epub 2022 Jun 4 doi: 10.1016/j.clnesp.2022.05.025. PMID: 35871919
Tanem KE, Stensvold E, Wilberg P, Skaare AB, Singh PB, Brandal P, Herlofson BB
Support Care Cancer 2022 Jul;30(7):6155-6162. Epub 2022 Apr 15 doi: 10.1007/s00520-022-07048-9. PMID: 35426047Free PMC Article
Stadskleiv K, Stensvold E, Stokka K, Bechensteen AG, Brandal P
Clin Neuropsychol 2022 Apr;36(3):600-625. Epub 2020 Jul 30 doi: 10.1080/13854046.2020.1794045. PMID: 32729777

Recent systematic reviews

Ajithkumar T, Avanzo M, Yorke E, Tsang DS, Milano MT, Olch AJ, Merchant TE, Dieckmann K, Mahajan A, Fuji H, Paulino AC, Timmermann B, Marks LB, Bentzen SM, Jackson A, Constine LS
Int J Radiat Oncol Biol Phys 2024 Jun 1;119(2):655-668. Epub 2024 Feb 1 doi: 10.1016/j.ijrobp.2023.12.043. PMID: 38300187
Raghuram CP, Moreno L, Zacharoulis S
J Neurooncol 2012 Feb;106(3):441-7. Epub 2011 Aug 18 doi: 10.1007/s11060-011-0690-6. PMID: 21850536

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