U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal papillary muscle morphology

MedGen UID:
1376889
•Concept ID:
C4476781
•
Anatomical Abnormality
Synonym: Morphological abnormality of the papillary muscles
 
HPO: HP:0025445

Definition

Any structural anomaly of the papillary muscles of the left ventricle. [from HPO]

Professional guidelines

PubMed

New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study.
Le Tourneau T, Le Scouarnec S, Cueff C, Bernstein D, Aalberts JJJ, Lecointe S, Mérot J, Bernstein JA, Oomen T, Dina C, Karakachoff M, Desal H, Al Habash O, Delling FN, Capoulade R, Suurmeijer AJH, Milan D, Norris RA, Markwald R, Aikawa E, Slaugenhaupt SA, Jeunemaitre X, Hagège A, Roussel JC, Trochu JN, Levine RA, Kyndt F, Probst V, Le Marec H, Schott JJ
Eur Heart J 2018 Apr 14;39(15):1269-1277. doi: 10.1093/eurheartj/ehx505. PMID: 29020406Free PMC Article
Diagnosis and treatment of branchial cleft anomalies in UKMMC: a 10-year retrospective study.
Zaifullah S, Yunus MR, See GB
Eur Arch Otorhinolaryngol 2013 Mar;270(4):1501-6. Epub 2012 Oct 7 doi: 10.1007/s00405-012-2200-7. PMID: 23053382
Cross-sectional echocardiographic assessment of atrioventricular septal defect: basic morphology and preoperative risk factors.
Smallhorn JF
Echocardiography 2001 Jul;18(5):415-32. doi: 10.1046/j.1540-8175.2001.00415.x. PMID: 11466155

Recent clinical studies

Etiology

Renal Cell Carcinoma With Fibromyomatous Stroma-The Whole Story.
Shah RB
Adv Anat Pathol 2022 May 1;29(3):168-177. doi: 10.1097/PAP.0000000000000337. PMID: 35249990
Anomalous papillary muscles-Implications in the surgical treatment of hypertrophic obstructive cardiomyopathy.
Lentz Carvalho J, Schaff HV, Morris CS, Nishimura RA, Ommen SR, Maleszewski JJ, Dearani JA
J Thorac Cardiovasc Surg 2022 Jan;163(1):83-89.e1. Epub 2020 Apr 15 doi: 10.1016/j.jtcvs.2020.04.007. PMID: 32414597
Mitral Valve Prolapse, Ventricular Arrhythmias, and Sudden Death.
Basso C, Iliceto S, Thiene G, Perazzolo Marra M
Circulation 2019 Sep 10;140(11):952-964. Epub 2019 Sep 9 doi: 10.1161/CIRCULATIONAHA.118.034075. PMID: 31498700
Repair for Congenital Mitral Valve Stenosis.
Delmo Walter EM, Hetzer R
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2018 Mar;21:46-57. doi: 10.1053/j.pcsu.2017.11.008. PMID: 29425525
Anatomy of the mitral subvalvular apparatus.
Krawczyk-Ożóg A, Hołda MK, Bolechała F, Siudak Z, Sorysz D, Dudek D, Klimek-Piotrowska W
J Thorac Cardiovasc Surg 2018 May;155(5):2002-2010. Epub 2017 Dec 23 doi: 10.1016/j.jtcvs.2017.12.061. PMID: 29397976

Diagnosis

Renal Cell Carcinoma With Fibromyomatous Stroma-The Whole Story.
Shah RB
Adv Anat Pathol 2022 May 1;29(3):168-177. doi: 10.1097/PAP.0000000000000337. PMID: 35249990
Mitral annular disjunction: A systematic review of the literature.
Bennett S, Thamman R, Griffiths T, Oxley C, Khan JN, Phan T, Patwala A, Heatlie G, Kwok CS
Echocardiography 2019 Aug;36(8):1549-1558. Epub 2019 Aug 5 doi: 10.1111/echo.14437. PMID: 31385360
Bands in the Heart: Multimodality Imaging Review.
Rajiah P, MacNamara J, Chaturvedi A, Ashwath R, Fulton NL, Goerne H
Radiographics 2019 Sep-Oct;39(5):1238-1263. Epub 2019 Aug 2 doi: 10.1148/rg.2019180176. PMID: 31373865
Mitral valve and papillary muscle abnormalities in hypertrophic obstructive cardiomyopathy.
Teo EP, Teoh JG, Hung J
Curr Opin Cardiol 2015 Sep;30(5):475-82. doi: 10.1097/HCO.0000000000000200. PMID: 26192489
Nonrheumatic mitral incompetence.
Yahini JH, Deutsch V, Miller HI, Shem-Tov A, Atlas P, Neufeld HN
Isr J Med Sci 1975 Sep;11(9):928-67. PMID: 1184367

Therapy

Anomalous papillary muscles-Implications in the surgical treatment of hypertrophic obstructive cardiomyopathy.
Lentz Carvalho J, Schaff HV, Morris CS, Nishimura RA, Ommen SR, Maleszewski JJ, Dearani JA
J Thorac Cardiovasc Surg 2022 Jan;163(1):83-89.e1. Epub 2020 Apr 15 doi: 10.1016/j.jtcvs.2020.04.007. PMID: 32414597
Pharmacotherapy in inherited and acquired ventricular arrhythmia in structurally normal adult hearts.
Ortmans S, Daval C, Aguilar M, Compagno P, Cadrin-Tourigny J, Dyrda K, Rivard L, Tadros R
Expert Opin Pharmacother 2019 Dec;20(17):2101-2114. Epub 2019 Sep 30 doi: 10.1080/14656566.2019.1669561. PMID: 31566420
Characteristics of mitral valve leaflet length in patients with pectus excavatum: A single center cross-sectional study.
Nomura K, Ajiro Y, Nakano S, Matsushima M, Yamaguchi Y, Hatakeyama N, Ohata M, Sakuma M, Nonaka T, Harii M, Utsumi M, Sakamoto K, Iwade K, Kuninaka N
PLoS One 2019;14(2):e0212165. Epub 2019 Feb 11 doi: 10.1371/journal.pone.0212165. PMID: 30742685Free PMC Article
Techniques for ensuring the correct length of new mitral chords.
Duran CM, Pekar F
J Heart Valve Dis 2003 Mar;12(2):156-61. PMID: 12701786
Morphologic features of the normal and abnormal mitral valve.
Roberts WC
Am J Cardiol 1983 Mar 15;51(6):1005-28. doi: 10.1016/s0002-9149(83)80181-7. PMID: 6338691

Prognosis

Transthoracic echocardiography for arrhythmic mitral valve prolapse: Phenotypic characterization as first step.
Vriz O, Eltayeb A, Landi I, Anwar K, Alenazy A, Hiristova K, Kasprzak J, D'Andrea A, Amro B, Limongelli G, Bossone E, Imazio M
Echocardiography 2022 Sep;39(9):1158-1170. Epub 2022 Aug 27 doi: 10.1111/echo.15439. PMID: 36029124
Mitral Valve Prolapse, Ventricular Arrhythmias, and Sudden Death.
Basso C, Iliceto S, Thiene G, Perazzolo Marra M
Circulation 2019 Sep 10;140(11):952-964. Epub 2019 Sep 9 doi: 10.1161/CIRCULATIONAHA.118.034075. PMID: 31498700
Mitral annular disjunction: A systematic review of the literature.
Bennett S, Thamman R, Griffiths T, Oxley C, Khan JN, Phan T, Patwala A, Heatlie G, Kwok CS
Echocardiography 2019 Aug;36(8):1549-1558. Epub 2019 Aug 5 doi: 10.1111/echo.14437. PMID: 31385360
Repair for Congenital Mitral Valve Stenosis.
Delmo Walter EM, Hetzer R
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2018 Mar;21:46-57. doi: 10.1053/j.pcsu.2017.11.008. PMID: 29425525
Nonrheumatic mitral incompetence.
Yahini JH, Deutsch V, Miller HI, Shem-Tov A, Atlas P, Neufeld HN
Isr J Med Sci 1975 Sep;11(9):928-67. PMID: 1184367

Clinical prediction guides

Apical papillary muscle displacement is a prevalent feature and a phenotypic precursor of apical hypertrophic cardiomyopathy.
Filomena D, Vandenberk B, Dresselaers T, Willems R, Van Cleemput J, Olivotto I, Robyns T, Bogaert J
Eur Heart J Cardiovasc Imaging 2023 Jul 24;24(8):1009-1016. doi: 10.1093/ehjci/jead078. PMID: 37114736
Mitral annular disjunction: A systematic review of the literature.
Bennett S, Thamman R, Griffiths T, Oxley C, Khan JN, Phan T, Patwala A, Heatlie G, Kwok CS
Echocardiography 2019 Aug;36(8):1549-1558. Epub 2019 Aug 5 doi: 10.1111/echo.14437. PMID: 31385360
Anatomy of the mitral subvalvular apparatus.
Krawczyk-Ożóg A, Hołda MK, Bolechała F, Siudak Z, Sorysz D, Dudek D, Klimek-Piotrowska W
J Thorac Cardiovasc Surg 2018 May;155(5):2002-2010. Epub 2017 Dec 23 doi: 10.1016/j.jtcvs.2017.12.061. PMID: 29397976
Congenital malformations of the mitral valve.
Séguéla PE, Houyel L, Acar P
Arch Cardiovasc Dis 2011 Aug;104(8-9):465-79. Epub 2011 Aug 30 doi: 10.1016/j.acvd.2011.06.004. PMID: 21944149
The current and emerging role of cardiovascular magnetic resonance imaging in hypertrophic cardiomyopathy.
Maron MS
J Cardiovasc Transl Res 2009 Dec;2(4):415-25. Epub 2009 Nov 7 doi: 10.1007/s12265-009-9136-3. PMID: 20560000

Recent systematic reviews

Split cord malformation concomitant with spinal teratoma without open spinal dysraphism.
Hazneci J, Bastacı F, Börekci A, Öztürk ÖÇ, İş M, Somay A, Ekşi MŞ, Çelikoğlu E
Childs Nerv Syst 2022 Oct;38(10):1977-1986. Epub 2022 Jun 10 doi: 10.1007/s00381-022-05578-5. PMID: 35687168
Mitral annular disjunction: A systematic review of the literature.
Bennett S, Thamman R, Griffiths T, Oxley C, Khan JN, Phan T, Patwala A, Heatlie G, Kwok CS
Echocardiography 2019 Aug;36(8):1549-1558. Epub 2019 Aug 5 doi: 10.1111/echo.14437. PMID: 31385360
Clinical usefulness of random biopsies in diagnosis and treatment of non-muscle invasive bladder cancer: Systematic review and meta-analysis.
Subiela JD, Palou J, Esquinas C, Fernández Gómez JM, Rodríguez Faba O
Actas Urol Esp (Engl Ed) 2018 Jun;42(5):285-298. Epub 2017 Nov 21 doi: 10.1016/j.acuro.2017.10.001. PMID: 29169705

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...