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Paracentric inversion

MedGen UID:
137690
Concept ID:
C0333707
Cell or Molecular Dysfunction
Synonym: Paracentric Inversion
SNOMED CT: Paracentric inversion (68499005)

Definition

A chromosome inversion involving a segment that does not include the centromere. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParacentric inversion

Professional guidelines

PubMed

Shao Y, Li J, Lu J, Li H, Zhu Y, Jiang W, Yan J
Reprod Biol Endocrinol 2020 Aug 5;18(1):79. doi: 10.1186/s12958-020-00635-7. PMID: 32758287Free PMC Article
Xie P, Hu L, Tan Y, Gong F, Zhang S, Xiong B, Peng Y, Lu GX, Lin G
Fertil Steril 2019 Aug;112(2):336-342.e3. Epub 2019 May 15 doi: 10.1016/j.fertnstert.2019.03.041. PMID: 31103288
Poulsen H, Mikkelsen M, Holmgren G
Prenat Diagn 1981 Jan;1(1):35-42. doi: 10.1002/pd.1970010108. PMID: 7346810

Recent clinical studies

Etiology

Love RR, Redmond SN, Pombi M, Caputo B, Petrarca V, Della Torre A; Anopheles gambiae 1000 Genomes Consortium, Besansky NJ
G3 (Bethesda) 2019 Oct 7;9(10):3249-3262. doi: 10.1534/g3.119.400445. PMID: 31391198Free PMC Article
Madan K
Hum Genet 1995 Nov;96(5):503-15. doi: 10.1007/BF00197403. PMID: 8529995
Feldman GL, Weiss L, Phelan MC, Schroer RJ, Van Dyke DL
Am J Med Genet 1993 Sep 15;47(4):482-6. doi: 10.1002/ajmg.1320470410. PMID: 8256810
Miller K, Raabe G, Schlesinger C, Schulze B
Ann Genet 1990;33(4):225-7. PMID: 2095705
Madan K, Seabright M, Lindenbaum RH, Bobrow M
J Med Genet 1984 Dec;21(6):407-12. doi: 10.1136/jmg.21.6.407. PMID: 6392555Free PMC Article

Diagnosis

Cerrato A, Merolla F, Morra F, Celetti A
Int J Cancer 2018 Apr 1;142(7):1300-1308. Epub 2017 Oct 26 doi: 10.1002/ijc.31106. PMID: 29044514
Aiello V, Astolfi N, Gruppioni R, Buldrini B, Prontera P, Bonfatti A, Sensi A, Calzolari E
Genet Couns 2007;18(4):379-82. PMID: 18286818
Sanlaville D, Genevieve D, Bernardin C, Amiel J, Baumann C, de Blois MC, Cormier-Daire V, Gerard B, Gerard M, Le Merrer M, Parent P, Prieur F, Prieur M, Raoul O, Toutain A, Verloes A, Viot G, Romana S, Munnich A, Lyonnet S, Vekemans M, Turleau C
Eur J Hum Genet 2005 May;13(5):690-3. doi: 10.1038/sj.ejhg.5201383. PMID: 15770228
Madan K
Hum Genet 1995 Nov;96(5):503-15. doi: 10.1007/BF00197403. PMID: 8529995
Madan K, Seabright M, Lindenbaum RH, Bobrow M
J Med Genet 1984 Dec;21(6):407-12. doi: 10.1136/jmg.21.6.407. PMID: 6392555Free PMC Article

Therapy

Shao Y, Li J, Lu J, Li H, Zhu Y, Jiang W, Yan J
Reprod Biol Endocrinol 2020 Aug 5;18(1):79. doi: 10.1186/s12958-020-00635-7. PMID: 32758287Free PMC Article
Cuman C, Beyer CE, Brodie D, Fullston T, Lin JI, Willats E, Zander-Fox D, Mullen J
Hum Reprod 2018 Aug 1;33(8):1566-1576. doi: 10.1093/humrep/dey227. PMID: 30007310
Vargas-González R, de la Torre-Mondragón L, Aparicio-Rodríguez JM, Paniagua-Morgan F, López-Hernández G, Garrido-Hernández MA, Nuñez-Barrera S
Pediatr Dev Pathol 2010 Nov-Dec;13(6):486-91. Epub 2010 Mar 24 doi: 10.2350/10-01-0791-CR.1. PMID: 20334546
Abeliovich D, Dagan J, Kimchi-Sarfaty C, Zlotogora J
Am J Med Genet 1995 Jan 30;55(3):359-62. doi: 10.1002/ajmg.1320550322. PMID: 7726237
Schnur RE, Herzberg AJ, Spinner N, Kant JA, Magnusson M, McDonald-McGinn D, Rehberg K, Honig PJ, Zackai EH
J Am Acad Dermatol 1993 Feb;28(2 Pt 2):364-70. PMID: 8436660

Prognosis

Xie P, Hu L, Tan Y, Gong F, Zhang S, Xiong B, Peng Y, Lu GX, Lin G
Fertil Steril 2019 Aug;112(2):336-342.e3. Epub 2019 May 15 doi: 10.1016/j.fertnstert.2019.03.041. PMID: 31103288
Cuman C, Beyer CE, Brodie D, Fullston T, Lin JI, Willats E, Zander-Fox D, Mullen J
Hum Reprod 2018 Aug 1;33(8):1566-1576. doi: 10.1093/humrep/dey227. PMID: 30007310
Ronchi A, Cozzolino I, Zito Marino F, Accardo M, Montella M, Panarese I, Roccuzzo G, Toni G, Franco R, De Chiara A
Ann Diagn Pathol 2018 Jun;34:142-150. Epub 2018 Apr 9 doi: 10.1016/j.anndiagpath.2018.01.004. PMID: 29660566
Cerrato A, Merolla F, Morra F, Celetti A
Int J Cancer 2018 Apr 1;142(7):1300-1308. Epub 2017 Oct 26 doi: 10.1002/ijc.31106. PMID: 29044514
Crow TJ
Schizophr Res 2008 Jul;102(1-3):31-52. Epub 2008 May 23 doi: 10.1016/j.schres.2008.03.010. PMID: 18502103

Clinical prediction guides

Schubert I
Chromosoma 2018 Jun;127(2):229-234. Epub 2018 Apr 28 doi: 10.1007/s00412-018-0672-y. PMID: 29705818
Cerrato A, Merolla F, Morra F, Celetti A
Int J Cancer 2018 Apr 1;142(7):1300-1308. Epub 2017 Oct 26 doi: 10.1002/ijc.31106. PMID: 29044514
Madan K
Hum Genet 1995 Nov;96(5):503-15. doi: 10.1007/BF00197403. PMID: 8529995
Feldman GL, Weiss L, Phelan MC, Schroer RJ, Van Dyke DL
Am J Med Genet 1993 Sep 15;47(4):482-6. doi: 10.1002/ajmg.1320470410. PMID: 8256810
Poulsen H, Mikkelsen M, Holmgren G
Prenat Diagn 1981 Jan;1(1):35-42. doi: 10.1002/pd.1970010108. PMID: 7346810

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