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Michaelis-Gutmann bodies

MedGen UID:
137695
Concept ID:
C0333746
Finding
Synonyms: Malakoplakia; MG body; Michaelis-Gutmann body; Michaelis-Gutmann Body
SNOMED CT: Michaelis-Gutmann body (82662004); MG body (82662004)
 
HPO: HP:0033046

Definition

Basophilic intracytoplasmic inclusions in macrophages. The inclusions have a small, round laminated appearance. Electron microscopy of Michaelis-Gutmann bodies exhibits partially digested bacteria. [from HPO]

Term Hierarchy

Recent clinical studies

Etiology

Xia Z, Du D, Zhang Z, Hu Z, Liu Z
Int Urol Nephrol 2024 Jun;56(6):1779-1784. Epub 2024 Jan 18 doi: 10.1007/s11255-023-03920-7. PMID: 38236373
Șerban C, Toma A, Voicu DC, Popazu C, Firescu D, Țocu G, Mihailov R, Rebegea L
Medicina (Kaunas) 2023 Jan 12;59(1) doi: 10.3390/medicina59010156. PMID: 36676780Free PMC Article
Koutserimpas C, Ioannidis A, Demonakou M, Siaperas P, Skarpas A, Velimezis G, Karanikas I
G Chir 2018 Mar-Apr;39(2):97-100. PMID: 29694309
de Peralta-Venturina MN, Clubb FJ, Kielhofner MA
Am J Clin Pathol 1994 Oct;102(4):459-63. doi: 10.1093/ajcp/102.4.459. PMID: 7942603
Dobyan DC, Truong LD, Eknoyan G
Am J Kidney Dis 1993 Aug;22(2):243-52. doi: 10.1016/s0272-6386(12)70313-x. PMID: 8352248

Diagnosis

Chaudhry N, Vazzano J, Parwani A
Pathol Res Pract 2022 Sep;237:153852. Epub 2022 Mar 28 doi: 10.1016/j.prp.2022.153852. PMID: 35878530
Cięszczyk K, Puderecki M, Wronecki L, Burdan F, Szumiło J
Folia Med Cracov 2019;59(2):67-74. PMID: 31659350
Lane RJ, Kradin R, Xia D, Buchan CA, Turbett S, Kotton CN, Mansour MK
Transplant Proc 2019 Apr;51(3):871-874. Epub 2019 Jan 8 doi: 10.1016/j.transproceed.2018.11.008. PMID: 30979478Free PMC Article
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Yousef GM, Naghibi B, Hamodat MM
Arch Pathol Lab Med 2007 Feb;131(2):297-300. doi: 10.5858/2007-131-297-MOTUT. PMID: 17284117

Therapy

Chaudhry N, Vazzano J, Parwani A
Pathol Res Pract 2022 Sep;237:153852. Epub 2022 Mar 28 doi: 10.1016/j.prp.2022.153852. PMID: 35878530
Cięszczyk K, Puderecki M, Wronecki L, Burdan F, Szumiło J
Folia Med Cracov 2019;59(2):67-74. PMID: 31659350
Lane RJ, Kradin R, Xia D, Buchan CA, Turbett S, Kotton CN, Mansour MK
Transplant Proc 2019 Apr;51(3):871-874. Epub 2019 Jan 8 doi: 10.1016/j.transproceed.2018.11.008. PMID: 30979478Free PMC Article
Hyun KH, Shin HD, Kim DH
Korean J Intern Med 2013 Jul;28(4):475-80. Epub 2013 Jul 1 doi: 10.3904/kjim.2013.28.4.475. PMID: 23864806Free PMC Article
Kohl SK, Hans CP
Arch Pathol Lab Med 2008 Jan;132(1):113-7. doi: 10.5858/2008-132-113-CM. PMID: 18181662

Prognosis

Zhang Y, Byrnes K, Lam-Himlin D, Pittman M, Pezhouh M, Gonzalez RS, Alruwaii Z, Larman T, Miller JA, Matoso A, Oshima K, Epstein JI, Montgomery EA, Voltaggio L
Am J Surg Pathol 2020 Sep;44(9):1251-1258. doi: 10.1097/PAS.0000000000001491. PMID: 32301754
Cięszczyk K, Puderecki M, Wronecki L, Burdan F, Szumiło J
Folia Med Cracov 2019;59(2):67-74. PMID: 31659350
Hyun KH, Shin HD, Kim DH
Korean J Intern Med 2013 Jul;28(4):475-80. Epub 2013 Jul 1 doi: 10.3904/kjim.2013.28.4.475. PMID: 23864806Free PMC Article
Kohl SK, Hans CP
Arch Pathol Lab Med 2008 Jan;132(1):113-7. doi: 10.5858/2008-132-113-CM. PMID: 18181662
Dobyan DC, Truong LD, Eknoyan G
Am J Kidney Dis 1993 Aug;22(2):243-52. doi: 10.1016/s0272-6386(12)70313-x. PMID: 8352248

Clinical prediction guides

Zhang XY, Li J, Chen SL, Li Y, Wang H, He JH
Diagn Pathol 2023 Aug 29;18(1):97. doi: 10.1186/s13000-023-01383-z. PMID: 37644531Free PMC Article
Hubbard L, Iriana S, Carey A, Odrobina R, Sossenheimer M, Rogers D
Pancreas 2020 Mar;49(3):455-460. doi: 10.1097/MPA.0000000000001497. PMID: 32168251
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Ho KL
Arch Pathol Lab Med 1989 Aug;113(8):874-9. PMID: 2757488
Paquin F, Schick E, Parent C
Urology 1983 Feb;21(2):194-8. doi: 10.1016/0090-4295(83)90026-2. PMID: 6297143

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