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Eccrine papillary adenoma

MedGen UID:
137747
•Concept ID:
C0334350
•
Neoplastic Process
Synonyms: eccrine papillary adenoma; Eccrine papillary adenoma of skin; eccrine papillary adenoma of skin; Papillary Eccrine Adenoma; Papillary eccrine adenoma
SNOMED CT: Eccrine papillary adenoma (10060008); Eccrine papillary adenoma of skin (253021007); Eccrine papillary adenoma (253021007)
 
Monarch Initiative: MONDO:0003450

Definition

A benign neoplasm arising from the sweat glands. It is characterized by the presence of eccrine ducts in the dermis containing intraluminal papillary projections. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEccrine papillary adenoma

Professional guidelines

PubMed

CO(2) laser in the management of eccrine hidrocystomas: a retrospective study.
Fazia G, Cannarozzo G, Bennardo L, Nisticò SP
Lasers Med Sci 2022 Mar;37(2):1365-1369. Epub 2021 Sep 27 doi: 10.1007/s10103-021-03424-9. PMID: 34570293
Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review.
Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J
ANZ J Surg 2021 Oct;91(10):1996-2001. Epub 2021 Feb 1 doi: 10.1111/ans.16626. PMID: 33522696
Evaluation and management of the patient with multiple syringomas: A systematic review of the literature.
Williams K, Shinkai K
J Am Acad Dermatol 2016 Jun;74(6):1234-1240.e9. Epub 2016 Feb 3 doi: 10.1016/j.jaad.2015.12.006. PMID: 26850654

Recent clinical studies

Etiology

Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
Generalized eruptive syringomas.
Huang A, Taylor G, Liebman TN
Dermatol Online J 2017 Sep 15;23(9) PMID: 29469728
Poroma: a review of eccrine, apocrine, and malignant forms.
Sawaya JL, Khachemoune A
Int J Dermatol 2014 Sep;53(9):1053-61. Epub 2014 Apr 2 doi: 10.1111/ijd.12448. PMID: 24697501
A reappraisal of eyelid eccrine and apocrine hidrocystomas: microanatomic and immunohistochemical studies of 40 lesions.
Jakobiec FA, Zakka FR
Am J Ophthalmol 2011 Feb;151(2):358-74.e2. Epub 2010 Dec 18 doi: 10.1016/j.ajo.2010.08.028. PMID: 21168812
Aggressive digital papillary adenocarcinoma (aggressive digital papillary adenoma and adenocarcinoma revisited).
Duke WH, Sherrod TT, Lupton GP
Am J Surg Pathol 2000 Jun;24(6):775-84. doi: 10.1097/00000478-200006000-00002. PMID: 10843279

Diagnosis

Adnexal and Sebaceous Carcinomas.
Seger EW, Neill BC, Tolkachjov SN
Dermatol Clin 2023 Jan;41(1):117-132. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.010. PMID: 36410972
A systematic review of periungual eccrine neoplasms.
Rao EM, Knackstedt TJ
Int J Dermatol 2022 Jul;61(7):812-820. Epub 2021 Sep 8 doi: 10.1111/ijd.15893. PMID: 34494261
Apocrine and eccrine hidrocystomas: a clinicopathological study.
Koumaki D, Papadakis M, Lagoudaki E, Manios GA, Kassotakis D, Doxastaki A, Krasagakis K, Manios A
Acta Dermatovenerol Alp Pannonica Adriat 2021 Jun;30(2):53-56. PMID: 34169699
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Microcystic Adnexal Carcinoma: A Review of the Literature.
Gordon S, Fischer C, Martin A, Rosman IS, Council ML
Dermatol Surg 2017 Aug;43(8):1012-1016. doi: 10.1097/DSS.0000000000001142. PMID: 28654578

Therapy

Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
Eccrine poromatosis following chemotherapy and radiation therapy.
Nguyen K, Kim G, Chiu M
Dermatol Online J 2019 Nov 15;25(11) PMID: 32045152
Eccrine porocarcinoma.
Brown CW Jr, Dy LC
Dermatol Ther 2008 Nov-Dec;21(6):433-8. doi: 10.1111/j.1529-8019.2008.00243.x. PMID: 19076620
Multiple eccrine hidrocystomas.
Lee MR, Ryman W
Australas J Dermatol 2004 Aug;45(3):178-80. doi: 10.1111/j.1440-0960.2004.00084.x. PMID: 15250898
Malignant eccrine spiradenoma.
Mirza I, Kloss R, Sieber SC
Arch Pathol Lab Med 2002 May;126(5):591-4. doi: 10.5858/2002-126-0591-MES. PMID: 11958666

Prognosis

Adnexal and Sebaceous Carcinomas.
Seger EW, Neill BC, Tolkachjov SN
Dermatol Clin 2023 Jan;41(1):117-132. Epub 2022 Oct 28 doi: 10.1016/j.det.2022.07.010. PMID: 36410972
Microcystic Adnexal Carcinoma: A Review of the Literature.
Gordon S, Fischer C, Martin A, Rosman IS, Council ML
Dermatol Surg 2017 Aug;43(8):1012-1016. doi: 10.1097/DSS.0000000000001142. PMID: 28654578
Dermatology clinics: what's new in dermatopathology: news in nonmelanocytic neoplasia.
Sidhu HK, Patel RV, Goldenberg G
Dermatol Clin 2012 Oct;30(4):623-41, vi. Epub 2012 Aug 13 doi: 10.1016/j.det.2012.06.009. PMID: 23021050
A reappraisal of eyelid eccrine and apocrine hidrocystomas: microanatomic and immunohistochemical studies of 40 lesions.
Jakobiec FA, Zakka FR
Am J Ophthalmol 2011 Feb;151(2):358-74.e2. Epub 2010 Dec 18 doi: 10.1016/j.ajo.2010.08.028. PMID: 21168812
Malignant eccrine spiradenoma: a meta-analysis of reported cases.
Andreoli MT, Itani KM
Am J Surg 2011 May;201(5):695-9. Epub 2010 Sep 20 doi: 10.1016/j.amjsurg.2010.04.015. PMID: 20851376

Clinical prediction guides

Apocrine and eccrine hidrocystomas: a clinicopathological study.
Koumaki D, Papadakis M, Lagoudaki E, Manios GA, Kassotakis D, Doxastaki A, Krasagakis K, Manios A
Acta Dermatovenerol Alp Pannonica Adriat 2021 Jun;30(2):53-56. PMID: 34169699
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Mammary-like glands of the vulva and their disorders.
van der Putte SC
Int J Gynecol Pathol 1994 Apr;13(2):150-60. doi: 10.1097/00004347-199404000-00009. PMID: 8005737
Eccrine porocarcinoma.
Akiyoshi E, Nogita T, Yamaguchi R, Toyoda H, Kawashima M, Hidano A
Dermatologica 1991;182(4):239-42. doi: 10.1159/000247804. PMID: 1653154
Eruptive hidradenoma.
Bevilacqua P, Bolognia J
Cutis 1990 Jul;46(1):69-72. PMID: 2166651

Recent systematic reviews

A systematic review of periungual eccrine neoplasms.
Rao EM, Knackstedt TJ
Int J Dermatol 2022 Jul;61(7):812-820. Epub 2021 Sep 8 doi: 10.1111/ijd.15893. PMID: 34494261
Evaluation and management of the patient with multiple syringomas: A systematic review of the literature.
Williams K, Shinkai K
J Am Acad Dermatol 2016 Jun;74(6):1234-1240.e9. Epub 2016 Feb 3 doi: 10.1016/j.jaad.2015.12.006. PMID: 26850654

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