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Oligoclonal T cell expansion

MedGen UID:
1377498
Concept ID:
C4479459
Cell or Molecular Dysfunction
Synonym: Oligoclonal T-cell expansions
 
HPO: HP:0031430

Definition

The presence of a population of T cells with a restricted T cell receptor (TCR) repertoire derived from a limited number of TCR clones. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOligoclonal T cell expansion

Professional guidelines

PubMed

Turner CT, Brown J, Shaw E, Uddin I, Tsaliki E, Roe JK, Pollara G, Sun Y, Heather JM, Lipman M, Chain B, Noursadeghi M
Front Immunol 2021;12:634489. Epub 2021 Feb 25 doi: 10.3389/fimmu.2021.634489. PMID: 33732256Free PMC Article
Meliconi R, Kingsley GH, Pitzalis C, Sakkas L, Panayi GS
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Recent clinical studies

Etiology

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Lancet Oncol 2019 Nov;20(11):1544-1555. Epub 2019 Sep 25 doi: 10.1016/S1470-2045(19)30514-5. PMID: 31563517Free PMC Article
Summer B, Sander CA, Przybilla B, Thomas P
Allergy 2001 Aug;56(8):767-70. doi: 10.1034/j.1398-9995.2001.056008767.x. PMID: 11488671
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Diagnosis

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Blood 1996 Apr 1;87(7):3032-44. PMID: 8639927
Even J, Lim A, Puisieux I, Ferradini L, Dietrich PY, Toubert A, Hercend T, Triebel F, Pannetier C, Kourilsky P
Res Immunol 1995 Feb;146(2):65-80. doi: 10.1016/0923-2494(96)80240-9. PMID: 7481075

Therapy

Coffey DG, Xu Y, Towlerton AMH, Kowanetz M, Hegde P, Darwish M, Yadav M, Blanchette C, Ruppert SM, Bertino S, Xu Q, Ferretti A, Weinheimer A, Hellmann M, Qin A, Thomas D, Warren EH, Ramnath N
Front Immunol 2022;13:961105. Epub 2022 Sep 9 doi: 10.3389/fimmu.2022.961105. PMID: 36159875Free PMC Article
Rejeski K, Wu Z, Blumenberg V, Kunz WG, Müller S, Kajigaya S, Gao S, Bücklein VL, Frölich L, Schmidt C, von Bergwelt-Baildon M, Feng X, Young NS, Subklewe M
Blood 2022 Nov 17;140(20):2175-2179. doi: 10.1182/blood.2022017015. PMID: 35776908Free PMC Article
Turner CT, Brown J, Shaw E, Uddin I, Tsaliki E, Roe JK, Pollara G, Sun Y, Heather JM, Lipman M, Chain B, Noursadeghi M
Front Immunol 2021;12:634489. Epub 2021 Feb 25 doi: 10.3389/fimmu.2021.634489. PMID: 33732256Free PMC Article
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ
Nature 2015 Apr 16;520(7547):373-7. Epub 2015 Mar 9 doi: 10.1038/nature14292. PMID: 25754329Free PMC Article
Epperson DE, Nakamura R, Saunthararajah Y, Melenhorst J, Barrett AJ
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Prognosis

Funk CR, Petersen CT, Jagirdar N, Ravindranathan S, Jaye DL, Flowers CR, Langston A, Waller EK
Int J Mol Sci 2018 Dec 19;19(12) doi: 10.3390/ijms19124118. PMID: 30572564Free PMC Article
Hirokawa M, Matsutani T, Horiuchi T, Kawabata Y, Kitabayashi A, Yoshioka T, Tsuruta Y, Suzuki R, Miura AB
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Kato T, Kurokawa M, Sasakawa H, Masuko-Hongo K, Matsui T, Sekine T, Tanaka C, Yamamoto K, Nishioka K
Arthritis Rheum 2000 Dec;43(12):2712-21. doi: 10.1002/1529-0131(200012)43:12<2712::AID-ANR11>3.0.CO;2-T. PMID: 11145029
Even J, Lim A, Puisieux I, Ferradini L, Dietrich PY, Toubert A, Hercend T, Triebel F, Pannetier C, Kourilsky P
Res Immunol 1995 Feb;146(2):65-80. doi: 10.1016/0923-2494(96)80240-9. PMID: 7481075

Clinical prediction guides

Funk CR, Petersen CT, Jagirdar N, Ravindranathan S, Jaye DL, Flowers CR, Langston A, Waller EK
Int J Mol Sci 2018 Dec 19;19(12) doi: 10.3390/ijms19124118. PMID: 30572564Free PMC Article
Motz GT, Eppert BL, Sun G, Wesselkamper SC, Linke MJ, Deka R, Borchers MT
J Immunol 2008 Dec 1;181(11):8036-43. doi: 10.4049/jimmunol.181.11.8036. PMID: 19017996
Lin WJ, Norris DA, Achziger M, Kotzin BL, Tomkinson B
J Invest Dermatol 2001 Dec;117(6):1546-53. doi: 10.1046/j.0022-202x.2001.01548.x. PMID: 11886521
Summer B, Sander CA, Przybilla B, Thomas P
Allergy 2001 Aug;56(8):767-70. doi: 10.1034/j.1398-9995.2001.056008767.x. PMID: 11488671
Even J, Lim A, Puisieux I, Ferradini L, Dietrich PY, Toubert A, Hercend T, Triebel F, Pannetier C, Kourilsky P
Res Immunol 1995 Feb;146(2):65-80. doi: 10.1016/0923-2494(96)80240-9. PMID: 7481075

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