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Wolff-Chaikoff Phenomenon

MedGen UID:
1377518
•Concept ID:
C4331762
•
Disease or Syndrome

Definition

Hypothyroidism induced by excessive levels of iodine in the blood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVWolff-Chaikoff Phenomenon

Recent clinical studies

Etiology

Non-autoimmune primary hypothyroidism in diabetic and non-diabetic chronic renal dysfunction.
Bando Y, Ushiogi Y, Okafuji K, Toya D, Tanaka N, Miura S
Exp Clin Endocrinol Diabetes 2002 Nov;110(8):408-15. doi: 10.1055/s-2002-36427. PMID: 12518252

Diagnosis

Iodine-Induced hypothyroidism.
Markou K, Georgopoulos N, Kyriazopoulou V, Vagenakis AG
Thyroid 2001 May;11(5):501-10. doi: 10.1089/105072501300176462. PMID: 11396709

Therapy

Myxedema Coma Precipitated by Iohexol: Case Report and Brief Literature Review on the Wolff-Chaikoff Effect.
Tng EL, Aung AT, Chong N
Thyroid 2022 Jun;32(6):739-743. Epub 2022 Mar 22 doi: 10.1089/thy.2022.0021. PMID: 35180827
Non-autoimmune primary hypothyroidism in diabetic and non-diabetic chronic renal dysfunction.
Bando Y, Ushiogi Y, Okafuji K, Toya D, Tanaka N, Miura S
Exp Clin Endocrinol Diabetes 2002 Nov;110(8):408-15. doi: 10.1055/s-2002-36427. PMID: 12518252
Iodine-Induced hypothyroidism.
Markou K, Georgopoulos N, Kyriazopoulou V, Vagenakis AG
Thyroid 2001 May;11(5):501-10. doi: 10.1089/105072501300176462. PMID: 11396709

Clinical prediction guides

Non-autoimmune primary hypothyroidism in diabetic and non-diabetic chronic renal dysfunction.
Bando Y, Ushiogi Y, Okafuji K, Toya D, Tanaka N, Miura S
Exp Clin Endocrinol Diabetes 2002 Nov;110(8):408-15. doi: 10.1055/s-2002-36427. PMID: 12518252
Iodine-Induced hypothyroidism.
Markou K, Georgopoulos N, Kyriazopoulou V, Vagenakis AG
Thyroid 2001 May;11(5):501-10. doi: 10.1089/105072501300176462. PMID: 11396709

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