Fibromyxolipoma

MedGen UID:: 137768
•Concept ID:: C0334470
•: Neoplastic Process

Synonym:	Myxolipoma
SNOMED CT:	Fibromyxolipoma (58243007); Myxolipoma (58243007)

Definition

A benign well-circumscribed tumor composed of mature adipocytes, characterized by areas of abundant fibrous tissue and extensive myxoid change. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVFibromyxolipoma

Neoplasm
- Neoplasm by Special Category
  - Benign neoplasm
    - Benign connective and soft tissue neoplasm
      - Benign lipomatous neoplasm
        Lipoma
        Fibromyxolipoma

Recent clinical studies

Etiology

Spindle Cell Lipoma With Florid Primary Follicular Lymphocytic Hyperplasia: A Novel Association With Potential Diagnostic Pitfalls.

Fattah YH, Liu SS, Susa J, Hanly A, Russo J, Karai LJ
Am J Dermatopathol 2023 Aug 1;45(8):563-566. doi: 10.1097/DAD.0000000000002483. PMID: 37462206

Dendritic fibromyxolipoma adherent to the median nerve in the forearm.

Dahlin LB, Ljungberg O
J Plast Surg Hand Surg 2012 Apr;46(2):120-3. doi: 10.3109/02844311.2010.503083. PMID: 22471261

Expression of bcl-2 oncoprotein in benign and malignant spindle cell tumors of soft tissue, skin, serosal surfaces, and gastrointestinal tract.

Suster S, Fisher C, Moran CA
Am J Surg Pathol 1998 Jul;22(7):863-72. doi: 10.1097/00000478-199807000-00008. PMID: 9669348

See all (3)

Diagnosis

A Giant Dendritic Fibromyxolipoma in the Right Thorax: A Rare Entity.

Li H, Zhu J, Shen L, Pan Z, Wu C, Wu Y
Chest 2023 Oct;164(4):e89-e91. doi: 10.1016/j.chest.2023.06.013. PMID: 37805252

FDG PET/CT in Dendritic Fibromyxolipoma of the Thigh.

Ji X, Nian S, Bai Y, Dong A
Clin Nucl Med 2022 Feb 1;47(2):e208-e209. doi: 10.1097/RLU.0000000000003930. PMID: 34653047

A Case Report of Dendritic Fibromyxolipoma in the Back of Pediatric Patient.

Jin Y, Zhang L
Klin Padiatr 2020 Nov;232(6):328-330. Epub 2020 Sep 11 doi: 10.1055/a-1183-4686. PMID: 32916747

Dendritic fibromyxolipoma: a variant of spindle cell lipoma with extensive myxoid change, with cytogenetic evidence.

Wong YP, Chia WK, Low SF, Mohamed-Haflah NH, Sharifah NA
Pathol Int 2014 Jul;64(7):346-51. doi: 10.1111/pin.12176. PMID: 25047505

Dendritic fibromyxolipoma in the right inguinal and perineum regions: a case report and review of the literature.

Zhang XJ, Zhou S, Nie K, Chen DF, Kui GJ, Zhang XH
Diagn Pathol 2013 Sep 20;8:157. doi: 10.1186/1746-1596-8-157. PMID: 24053125 Free PMC Article

See all (13)

Therapy

Selected case from the Arkadi M. Rywlin International Pathology Slide Seminar: sclerotic (fibroma-like) lipoma, dorsum of right hand.

Allen PW
Adv Anat Pathol 2013 Jan;20(1):68-72. doi: 10.1097/PAP.0b013e31827b65e3. PMID: 23232574

See all (1)

Prognosis

Dendritic fibromyxolipoma on the nasal tip in an old patient.

Han XC, Zheng LQ, Shang XL
Int J Clin Exp Pathol 2014;7(10):7064-7. Epub 2014 Sep 15 PMID: 25400797 Free PMC Article

Dendritic fibromyxolipoma adherent to the median nerve in the forearm.

Dahlin LB, Ljungberg O
J Plast Surg Hand Surg 2012 Apr;46(2):120-3. doi: 10.3109/02844311.2010.503083. PMID: 22471261

Extrathoracic solitary fibrous tumors: their histological variability and potentially aggressive behavior.

Hasegawa T, Matsuno Y, Shimoda T, Hasegawa F, Sano T, Hirohashi S
Hum Pathol 1999 Dec;30(12):1464-73. doi: 10.1016/s0046-8177(99)90169-7. PMID: 10667425

See all (3)