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Low Grade Endometrioid Stromal Sarcoma

MedGen UID:
Concept ID:
Neoplastic Process
Synonyms: Endolymphatic Stromal Myoses; Endolymphatic Stromal Myosis; Myoses, Endolymphatic Stromal; Myosis, Endolymphatic Stromal; Sarcoma, Endometrial Stromal, Low-Grade; Stromal Myoses, Endolymphatic; Stromal Myosis, Endolymphatic
SNOMED CT: Stromal myosis (128726006); Stromal endometriosis (128726006); Endometrial stromatosis (128726006); Endolymphatic stromal myosis (128726006); Endometrial stromal sarcoma, low grade (128726006); Low grade endometrial stromal sarcoma (699357004); Endometrioid stromal sarcoma, low grade (128726006)


An infiltrating mesenchymal tumor arising from the uterine corpus, cervix, vagina, and the ovary. It is characterized by the presence of oval to spindle-shape cells that resemble the cells of the endometrial stroma, without evidence of significant atypia and pleomorphism. Numerous small vessels are also present. It is usually characterized by indolent growth and late recurrences. [from NCI]

Professional guidelines


Gadducci A, Multinu F, De Vitis LA, Cosio S, Carinelli S, Aletti GD
Gynecol Oncol 2023 Apr;171:95-105. Epub 2023 Feb 24 doi: 10.1016/j.ygyno.2023.02.009. PMID: 36842409
Desar IME, Ottevanger PB, Benson C, van der Graaf WTA
Crit Rev Oncol Hematol 2018 Feb;122:10-20. Epub 2017 Dec 14 doi: 10.1016/j.critrevonc.2017.12.009. PMID: 29458779
Dizon DS, Birrer MJ
Discov Med 2014 Jun;17(96):339-45. PMID: 24979254

Recent clinical studies


Stolnicu S, Tunde C, Szilard G, Podoleanu C, Rozsnyai F
Pol J Pathol 2020;71(3):277-280. doi: 10.5114/pjp.2020.99795. PMID: 33112119
Masand RP
Arch Pathol Lab Med 2018 Apr;142(4):536-541. Epub 2018 Jan 2 doi: 10.5858/arpa.2017-0241-RA. PMID: 29293021

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