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Thoracic benign neoplasm

MedGen UID:
138065
•Concept ID:
C0346440
•
Neoplastic Process
Synonyms: Benign Neoplasm of the Thorax; benign neoplasm of the thorax; Benign neoplasm of thorax; Benign Neoplasm of Thorax; benign neoplasm of thorax; Benign Thoracic Neoplasm; benign thoracic neoplasm; Benign Thoracic Tumor; benign thoracic tumor; benign thoracic tumour; Benign Tumor of the Thorax; benign tumor of the thorax; Benign tumor of thorax; Benign Tumor of Thorax; benign tumor of thorax; benign tumour of the thorax; benign tumour of thorax; thoracic benign neoplasm; thoracic segment of trunk benign neoplasm
SNOMED CT: Benign neoplasm of thorax (255059002); Benign tumor of thorax (255059002)
 
Monarch Initiative: MONDO:0000634

Definition

A neoplasm that arises from any of the organs in the thoracic cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThoracic benign neoplasm

Professional guidelines

PubMed

SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection.
Wang Q, Gümüş ZH, Colarossi C, Memeo L, Wang X, Kong CY, Boffetta P
J Thorac Oncol 2023 Jan;18(1):31-46. Epub 2022 Oct 12 doi: 10.1016/j.jtho.2022.10.002. PMID: 36243387Free PMC Article
Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring.
Li W, Liu JB, Hou LK, Yu F, Zhang J, Wu W, Tang XM, Sun F, Lu HM, Deng J, Bai J, Li J, Wu CY, Lin QL, Lv ZW, Wang GR, Jiang GX, Ma YS, Fu D
Mol Cancer 2022 Jan 20;21(1):25. doi: 10.1186/s12943-022-01505-z. PMID: 35057806Free PMC Article
Diagnosis and Treatment of Hemoptysis.
Cordovilla R, Bollo de Miguel E, Nuñez Ares A, Cosano Povedano FJ, Herráez Ortega I, Jiménez Merchán R
Arch Bronconeumol 2016 Jul;52(7):368-77. Epub 2016 Feb 9 doi: 10.1016/j.arbres.2015.12.002. PMID: 26873518

Recent clinical studies

Etiology

Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
Thoracic Manifestations of Genitourinary Neoplasms and Treatment-related Complications.
Stowell JT, Betancourt-Cuellar SL, Carter BW, Wu CC, Walker CM
J Thorac Imaging 2019 May;34(3):W36-W48. doi: 10.1097/RTI.0000000000000382. PMID: 31009398
Leukemic Involvement in the Thorax.
Shroff GS, Truong MT, Carter BW, Benveniste MF, Kanagal-Shamanna R, Rauch G, Viswanathan C, Boddu PC, Daver N, Wu CC
Radiographics 2019 Jan-Feb;39(1):44-61. doi: 10.1148/rg.2019180069. PMID: 30620703
MR Imaging of Primary Chest Wall Neoplasms.
Bueno J, Lichtenberger JP 3rd, Rauch G, Carter BW
Top Magn Reson Imaging 2018 Apr;27(2):83-93. doi: 10.1097/RMR.0000000000000164. PMID: 29613963
ITMIG Classification of Mediastinal Compartments and Multidisciplinary Approach to Mediastinal Masses.
Carter BW, Benveniste MF, Madan R, Godoy MC, de Groot PM, Truong MT, Rosado-de-Christenson ML, Marom EM
Radiographics 2017 Mar-Apr;37(2):413-436. Epub 2017 Jan 27 doi: 10.1148/rg.2017160095. PMID: 28129068

Diagnosis

MRI-Based Stepwise Approach to Anterior Mediastinal Cystic Lesions for Diagnosis and Further Management.
Kim JH, Choe J, Kim HK, Lee HY
Korean J Radiol 2023 Jan;24(1):62-78. doi: 10.3348/kjr.2022.0606. PMID: 36606621Free PMC Article
Imaging of the Anterior/Prevascular Mediastinum.
Garrana SH, Rosado-de-Christenson ML
Radiol Clin North Am 2021 Mar;59(2):155-168. Epub 2021 Jan 11 doi: 10.1016/j.rcl.2020.10.003. PMID: 33551078
The new 8th TNM staging system of lung cancer and its potential imaging interpretation pitfalls and limitations with CT image demonstrations.
Feng SH, Yang ST
Diagn Interv Radiol 2019 Jul;25(4):270-279. doi: 10.5152/dir.2019.18458. PMID: 31295144Free PMC Article
Imaging of Oncologic Emergencies.
Iacobellis F, Perillo A, Iadevito I, Tanga M, Romano L, Grassi R, Nicola R, Scaglione M
Semin Ultrasound CT MR 2018 Apr;39(2):151-166. Epub 2017 Dec 15 doi: 10.1053/j.sult.2017.12.001. PMID: 29571552
Approaching the patient with an anterior mediastinal mass: a guide for clinicians.
Carter BW, Marom EM, Detterbeck FC
J Thorac Oncol 2014 Sep;9(9 Suppl 2):S102-9. doi: 10.1097/JTO.0000000000000294. PMID: 25396306

Therapy

Impact of immune checkpoint inhibitors on atherosclerosis progression in patients with lung cancer.
Drobni ZD, Gongora C, Taron J, Suero-Abreu GA, Karady J, Gilman HK, Supraja S, Nikolaidou S, Leeper N, Merkely B, Maurovich-Horvat P, Foldyna B, Neilan TG
J Immunother Cancer 2023 Jul;11(7) doi: 10.1136/jitc-2023-007307. PMID: 37433718Free PMC Article
Mediastinal Staging in Non-Small-Cell Lung Cancer: Saying Goodbye to Mediastinoscopy.
Dunne EG, Fick CN, Jones DR
J Clin Oncol 2023 Aug 1;41(22):3785-3790. Epub 2023 Jun 2 doi: 10.1200/JCO.23.00867. PMID: 37267507Free PMC Article
Invasive Procedures Associated With Lung Cancer Screening in Clinical Practice.
Manyak A, Seaburg L, Bohreer K, Kirtland SH, Hubka M, Gerbino AJ
Chest 2023 Aug;164(2):544-555. Epub 2023 Feb 11 doi: 10.1016/j.chest.2023.02.010. PMID: 36781101
Mediastinal staging: when and how?
D'Andrilli A, Maurizi G, Venuta F, Rendina EA
Gen Thorac Cardiovasc Surg 2020 Jul;68(7):725-732. Epub 2019 Dec 3 doi: 10.1007/s11748-019-01263-8. PMID: 31797211
Central venous obstruction in the thorax.
Collin G, Jones RG, Willis AP
Clin Radiol 2015 Jun;70(6):654-60. Epub 2015 Apr 2 doi: 10.1016/j.crad.2015.01.014. PMID: 25843485

Prognosis

Forecasting lung cancer incidence, mortality, and prevalence to year 2030.
Jakobsen E, Olsen KE, Bliddal M, Hornbak M, Persson GF, Green A
BMC Cancer 2021 Sep 3;21(1):985. doi: 10.1186/s12885-021-08696-6. PMID: 34479490Free PMC Article
Lymphatic Pathways of the Thorax: Predictable Patterns of Spread.
Lee GM, Stowell JT, Pope K, Carter BW, Walker CM
AJR Am J Roentgenol 2021 Mar;216(3):649-658. Epub 2020 Dec 30 doi: 10.2214/AJR.20.23523. PMID: 33377793
Progress in cancer mortality, incidence, and survival: a global overview.
Santucci C, Carioli G, Bertuccio P, Malvezzi M, Pastorino U, Boffetta P, Negri E, Bosetti C, La Vecchia C
Eur J Cancer Prev 2020 Sep;29(5):367-381. doi: 10.1097/CEJ.0000000000000594. PMID: 32740162
The new 8th TNM staging system of lung cancer and its potential imaging interpretation pitfalls and limitations with CT image demonstrations.
Feng SH, Yang ST
Diagn Interv Radiol 2019 Jul;25(4):270-279. doi: 10.5152/dir.2019.18458. PMID: 31295144Free PMC Article
Thoracic Manifestations of Genitourinary Neoplasms and Treatment-related Complications.
Stowell JT, Betancourt-Cuellar SL, Carter BW, Wu CC, Walker CM
J Thorac Imaging 2019 May;34(3):W36-W48. doi: 10.1097/RTI.0000000000000382. PMID: 31009398

Clinical prediction guides

Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
Fetal thoracic teratomas: mediastinal or pericardial?
Oliver ER, Didier RA, Horii SC, Hedrick HL, Khalek N, DeBari SE, Adzick NS, Coleman BG
Pediatr Radiol 2022 Nov;52(12):2319-2328. Epub 2022 Apr 26 doi: 10.1007/s00247-022-05367-x. PMID: 35471666
Lymphatic Pathways of the Thorax: Predictable Patterns of Spread.
Lee GM, Stowell JT, Pope K, Carter BW, Walker CM
AJR Am J Roentgenol 2021 Mar;216(3):649-658. Epub 2020 Dec 30 doi: 10.2214/AJR.20.23523. PMID: 33377793
Internal Thoracic Lymphadenopathy in Breast Cancer.
Cahoon AR, Smith BD, Yang WT
Radiographics 2017 Jul-Aug;37(4):1024-1036. doi: 10.1148/rg.2017160166. PMID: 28696856
Mucinous nevus.
Yokogawa M, Kamakura T, Ishiguro H, Ikeda M, Kodama H
J Dermatol 2005 Jan;32(1):30-3. doi: 10.1111/j.1346-8138.2005.tb00710.x. PMID: 15841658

Recent systematic reviews

The role of lipid metabolic reprogramming in tumor microenvironment.
Yang K, Wang X, Song C, He Z, Wang R, Xu Y, Jiang G, Wan Y, Mei J, Mao W
Theranostics 2023;13(6):1774-1808. Epub 2023 Mar 13 doi: 10.7150/thno.82920. PMID: 37064872Free PMC Article
Evaluation of Clinical and Safety Outcomes of Neoadjuvant Immunotherapy Combined With Chemotherapy for Patients With Resectable Esophageal Cancer: A Systematic Review and Meta-analysis.
Ge F, Huo Z, Cai X, Hu Q, Chen W, Lin G, Zhong R, You Z, Wang R, Lu Y, Wang R, Huang Q, Zhang H, Song A, Li C, Wen Y, Jiang Y, Liang H, He J, Liang W, Liu J
JAMA Netw Open 2022 Nov 1;5(11):e2239778. doi: 10.1001/jamanetworkopen.2022.39778. PMID: 36322089Free PMC Article
Systemic treatments for thymoma and thymic carcinoma: A systematic review.
Berghmans T, Durieux V, Holbrechts S, Jungels C, Lafitte JJ, Meert AP, Moretti L, Ocak S, Roelandts M, Girard N
Lung Cancer 2018 Dec;126:25-31. Epub 2018 Oct 18 doi: 10.1016/j.lungcan.2018.10.018. PMID: 30527189
Early palliative care for adults with advanced cancer.
Haun MW, Estel S, Rücker G, Friederich HC, Villalobos M, Thomas M, Hartmann M
Cochrane Database Syst Rev 2017 Jun 12;6(6):CD011129. doi: 10.1002/14651858.CD011129.pub2. PMID: 28603881Free PMC Article
Metabolic syndrome and risk of cancer: a systematic review and meta-analysis.
Esposito K, Chiodini P, Colao A, Lenzi A, Giugliano D
Diabetes Care 2012 Nov;35(11):2402-11. doi: 10.2337/dc12-0336. PMID: 23093685Free PMC Article

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