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Benign Osteoclastic Giant Cell-Rich Tumor of Bone

MedGen UID:
1380763
Concept ID:
C4316923
Neoplastic Process
Synonym: Benign Osteoclastic Giant Cell-Rich Tumor of the Bone

Definition

A giant cell tumor that arises from the bone and is characterized by the absence of local aggression and lack of metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Osteoclastic Giant Cell-Rich Tumor of Bone

Recent clinical studies

Etiology

Panagopoulos I, Andersen K, Gorunova L, Lund-Iversen M, Lobmaier I, Heim S
Cancer Genomics Proteomics 2022 Mar-Apr;19(2):163-177. doi: 10.21873/cgp.20312. PMID: 35181586Free PMC Article
Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tada K, Higuchi T, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H, Nojima T, Tsuchiya H
Int J Clin Oncol 2021 Mar;26(3):613-619. Epub 2020 Nov 23 doi: 10.1007/s10147-020-01836-1. PMID: 33225397
Lipplaa A, Dijkstra S, Gelderblom H
Curr Opin Oncol 2019 Jul;31(4):329-335. doi: 10.1097/CCO.0000000000000529. PMID: 30844887Free PMC Article
Gamage NM, Kashima TG, McNally MA, Gibbons CL, Smith R, Ostlere SJ, Athanasou NA
Skeletal Radiol 2013 Apr;42(4):595-9. Epub 2012 Dec 29 doi: 10.1007/s00256-012-1558-3. PMID: 23275027
O'Connell JX, Wehrli BM, Nielsen GP, Rosenberg AE
Am J Surg Pathol 2000 Mar;24(3):386-95. doi: 10.1097/00000478-200003000-00007. PMID: 10716152

Diagnosis

Kovacs SK, Manassaporn A, Nielsen GP, Hung YP
Histopathology 2023 May;82(6):794-811. Epub 2022 Dec 16 doi: 10.1111/his.14845. PMID: 36424903
Wakely PE Jr
Cancer Cytopathol 2022 Feb;130(2):120-127. Epub 2021 Oct 7 doi: 10.1002/cncy.22517. PMID: 34618411
Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tada K, Higuchi T, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H, Nojima T, Tsuchiya H
Int J Clin Oncol 2021 Mar;26(3):613-619. Epub 2020 Nov 23 doi: 10.1007/s10147-020-01836-1. PMID: 33225397
Gamage NM, Kashima TG, McNally MA, Gibbons CL, Smith R, Ostlere SJ, Athanasou NA
Skeletal Radiol 2013 Apr;42(4):595-9. Epub 2012 Dec 29 doi: 10.1007/s00256-012-1558-3. PMID: 23275027

Therapy

Lipplaa A, Dijkstra S, Gelderblom H
Curr Opin Oncol 2019 Jul;31(4):329-335. doi: 10.1097/CCO.0000000000000529. PMID: 30844887Free PMC Article

Prognosis

Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Gamage NM, Kashima TG, McNally MA, Gibbons CL, Smith R, Ostlere SJ, Athanasou NA
Skeletal Radiol 2013 Apr;42(4):595-9. Epub 2012 Dec 29 doi: 10.1007/s00256-012-1558-3. PMID: 23275027
Boneschi V, Parafioriti A, Armiraglio E, Gaiani F, Brambilla L
J Cutan Pathol 2009 Oct;36 Suppl 1:20-4. Epub 2009 Feb 4 doi: 10.1111/j.1600-0560.2008.01202.x. PMID: 19222697
de Silva MV, Reid R
Ann Diagn Pathol 2003 Aug;7(4):205-13. doi: 10.1016/s1092-9134(03)00048-0. PMID: 12913842
O'Connell JX, Wehrli BM, Nielsen GP, Rosenberg AE
Am J Surg Pathol 2000 Mar;24(3):386-95. doi: 10.1097/00000478-200003000-00007. PMID: 10716152

Clinical prediction guides

Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Mirra JM, Finerman G, Lindholm S
Clin Orthop Relat Res 1980 Jun;(149):305-9. PMID: 7408316

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