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Abnormal morphology of the chordae tendinae of the mitral valve

MedGen UID:
1381439
Concept ID:
C4476826
Anatomical Abnormality
HPO: HP:0025523

Definition

A structural anomaly of the chordae tendinae of the mitral valve, whose main function is to transmit the contraction and relaxation of the papillary muscles during the cardiac cycle, thus ensuring the closing of the leaflets of the mitral valve. [from HPO]

Professional guidelines

PubMed

O'rourke RA, Crawford MH
Curr Probl Cardiol 1976 Mar-Apr;1(1):1-60. doi: 10.1016/s0146-2806(76)80006-0. PMID: 1017208

Recent clinical studies

Etiology

Krawczyk-Ożóg A, Hołda MK, Bolechała F, Siudak Z, Sorysz D, Dudek D, Klimek-Piotrowska W
J Thorac Cardiovasc Surg 2018 May;155(5):2002-2010. Epub 2017 Dec 23 doi: 10.1016/j.jtcvs.2017.12.061. PMID: 29397976
Fattouch K, Murana G, Castrovinci S, Nasso G, Mossuto C, Corrado E, Ruvolo G, Speziale G
Interact Cardiovasc Thorac Surg 2012 Oct;15(4):644-50. Epub 2012 Jul 3 doi: 10.1093/icvts/ivs195. PMID: 22761124Free PMC Article
Gualano SK, Bolling SF, Gordon D, Wilson A, Bach DS
Pacing Clin Electrophysiol 2007 Jan;30 Suppl 1:S156-9. doi: 10.1111/j.1540-8159.2007.00628.x. PMID: 17302695
Boudoulas H
J Heart Valve Dis 1992 Nov;1(2):175-88. PMID: 1341625
Virmani R, Atkinson JB, Forman MB
Herz 1988 Aug;13(4):215-26. PMID: 3049284

Diagnosis

Arbic N, Dragulescu A, Mertens L, Villemain O
J Vis Exp 2021 Jun 3;(172) doi: 10.3791/62574. PMID: 34152324
Rajiah P, MacNamara J, Chaturvedi A, Ashwath R, Fulton NL, Goerne H
Radiographics 2019 Sep-Oct;39(5):1238-1263. Epub 2019 Aug 2 doi: 10.1148/rg.2019180176. PMID: 31373865
Boudoulas H
J Heart Valve Dis 1992 Nov;1(2):175-88. PMID: 1341625
Virmani R, Atkinson JB, Forman MB
Herz 1988 Aug;13(4):215-26. PMID: 3049284
Yahini JH, Deutsch V, Miller HI, Shem-Tov A, Atlas P, Neufeld HN
Isr J Med Sci 1975 Sep;11(9):928-67. PMID: 1184367

Therapy

Sun F, Chen Y, Ren W, Zhang Y, Wu D, Chen X, Ma C, Li D
Int J Cardiol 2017 Jan 15;227:602-610. Epub 2016 Oct 29 doi: 10.1016/j.ijcard.2016.10.090. PMID: 27814918
Fattouch K, Murana G, Castrovinci S, Nasso G, Mossuto C, Corrado E, Ruvolo G, Speziale G
Interact Cardiovasc Thorac Surg 2012 Oct;15(4):644-50. Epub 2012 Jul 3 doi: 10.1093/icvts/ivs195. PMID: 22761124Free PMC Article
Duran CM, Pekar F
J Heart Valve Dis 2003 Mar;12(2):156-61. PMID: 12701786
Roberts WC
Am J Cardiol 1983 Mar 15;51(6):1005-28. doi: 10.1016/s0002-9149(83)80181-7. PMID: 6338691
Fowler NO, van der Bel-Kahn JM
Am J Cardiol 1979 Jul;44(1):148-57. doi: 10.1016/0002-9149(79)90264-9. PMID: 377933

Prognosis

Sun F, Chen Y, Ren W, Zhang Y, Wu D, Chen X, Ma C, Li D
Int J Cardiol 2017 Jan 15;227:602-610. Epub 2016 Oct 29 doi: 10.1016/j.ijcard.2016.10.090. PMID: 27814918
Osovska N, Kuzminova N, Ovcharuk M, Serhiychuk O
Georgian Med News 2016 Jun;(255):66-77. PMID: 27441539
Delmo Walter EM, Komoda T, Siniawski H, Miera O, Van Praagh R, Hetzer R
Eur J Cardiothorac Surg 2013 Mar;43(3):473-81; discussion 481-2. Epub 2012 Aug 23 doi: 10.1093/ejcts/ezs325. PMID: 22922555
Fattouch K, Murana G, Castrovinci S, Nasso G, Mossuto C, Corrado E, Ruvolo G, Speziale G
Interact Cardiovasc Thorac Surg 2012 Oct;15(4):644-50. Epub 2012 Jul 3 doi: 10.1093/icvts/ivs195. PMID: 22761124Free PMC Article
Yahini JH, Deutsch V, Miller HI, Shem-Tov A, Atlas P, Neufeld HN
Isr J Med Sci 1975 Sep;11(9):928-67. PMID: 1184367

Clinical prediction guides

Krawczyk-Ożóg A, Hołda MK, Bolechała F, Siudak Z, Sorysz D, Dudek D, Klimek-Piotrowska W
J Thorac Cardiovasc Surg 2018 May;155(5):2002-2010. Epub 2017 Dec 23 doi: 10.1016/j.jtcvs.2017.12.061. PMID: 29397976
Sun F, Chen Y, Ren W, Zhang Y, Wu D, Chen X, Ma C, Li D
Int J Cardiol 2017 Jan 15;227:602-610. Epub 2016 Oct 29 doi: 10.1016/j.ijcard.2016.10.090. PMID: 27814918
Boon R, Hazekamp M, Hoohenkerk G, Rijlaarsdam M, Schoof P, Koolbergen D, Heredia L, Dion R
Eur J Cardiothorac Surg 2007 Jul;32(1):143-8. Epub 2007 May 2 doi: 10.1016/j.ejcts.2007.03.035. PMID: 17478093
Virmani R, Atkinson JB, Forman MB
Herz 1988 Aug;13(4):215-26. PMID: 3049284
Effron MK
J Am Coll Cardiol 1983 Apr;1(4):1018-23. doi: 10.1016/s0735-1097(83)80103-x. PMID: 6833642

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